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Brodsky, US
Barbara Brodsky, Brookline, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120116053 | EXPRESSION OF TRIPLE-HELICAL COLLAGEN-LIKE PRODUCTS IN E.COLI - Recombinant bacterial triple-helical collagen-like proteins comprising two or more repetitive sequences of Gly-Xaa-Yaa yielding high-stability polymeric constructs without the need for post-translational modifications and which may incorporate one or more functional domains of biological or structural importance. The polymers are capable of high-yield production for a variety of applications | 05-10-2012 |
Barbara M. Brodsky, Kendall Park, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090176971 | Method for Determining Thermal Stability of Collagen or Collagen-Like Peptide - The present invention is a method for determining the thermal stability of a collagen peptide, collagen-like peptide or triple-helix construct with the repeating peptide unit Gly-Xaa | 07-09-2009 |
Elizabeth Adleberg Brodsky, Austin, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20130041882 | Technology for web site crawling, including action sequences for selecting non-hypertext-link parameters - A web site page has a reference for providing an address for a next page. The web site is crawled by the crawler program, which parses the reference from one of the web pages and sends the reference to an applet running in the browser. The address for the next page is determined by the browser responsive to the reference and is sent to the crawler. | 02-14-2013 |
Ethan Brodsky, Madison, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20110069175 | VISION SYSTEM AND METHOD FOR MOTION ADAPTIVE INTEGRATION OF IMAGE FRAMES - A night vision device and method for filtering a series of image frames that depict a moving subject, which thereby improves the signal-to-noise ratio of each image frame, is provided. A composite image is formed for each image frame by combining pixel values in a current image frame with pixel values in composite images corresponding to image frames acquired before the current image frame. Additionally, pixels values in image frames acquired subsequent to the acquisition of the current image frame are included when forming the composite image. A bi-directional recursive filter is used to weight the contributions from the previous composite images and subsequent image frames with a decay constant. Motion of the imaging system is optionally compensated for by establishing a moving reference frame and shifting the image frames to account for this motion; thus, registering the image frames before filtering the current image frame. | 03-24-2011 |
Ethan K. Brodsky, Madison, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20120256625 | Method for Accelerated High Resolution Chemical Species Separation for Magnetic Resonance Imaging - A method for producing an image of a subject with a magnetic resonance imaging (MRI) system is provided. Image data is acquired at a sequence of multiple echo times occurring within two or more repetition times (TRs). Odd-numbered echoes are sampled during odd-numbered TRs, and even-numbered echoes are sampled during even-numbered TRs. Images are reconstructed and used to calculate the respective signal contributions of two or more chemical species using, for example, an IDEAL separation technique. The respective signal contributions are then used to produce images that depicts substantially only one of the chemical species. For example, separated water and fat images may be produced. | 10-11-2012 |
Gary Brodsky, Denver, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20090175836 | PRELAMIN A PRE PEPTIDE AS A UNIVERSAL STEM CELL DIFFERENTIATION SIGNAL - Disclosed is the use of prelamin A pre peptide and homologues or analogs thereof for the induction of cell differentiation and tissue or organ growth and repair processes. The invention extends to virtually any cell, including both embryonic and non-embryonic stem cells, such as stem cells that are progenitors for a wide variety of cell and tissue types. Also disclosed is the use of prelamin A pre peptide and prelamin A to determine and establish cell morphology and tissue architecture. Treatment of a variety of diseases and conditions, as well as cosmetic, general health, and anti-aging applications are described. | 07-09-2009 |
| 20100105625 | Product and Methods for Diagnosis and Therapy for Cardiac and Skeletal Muscle Disorders - Disclosed are products and methods to promote myoblast activation and cardiac and skeletal muscle growth or regeneration, and to treat heart and skeletal muscle diseases, based on the identification of cellular processes affected by prelamin A processing. | 04-29-2010 |
James White Brodsky, Dallas, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090149861 | JOINT FUSION APPARATUS FOR THE ANKLE-TYPE JOINT AND ARTHRODETIC PIN FOR USE IN SAID APPARATUS - Arthrodesis apparatus for first and second bones ( | 06-11-2009 |
Jason Adam Brodsky, Nashua, NH US
| Patent application number | Description | Published |
|---|---|---|
| 20120028154 | FUEL CELL HAVING IMPROVED THERMAL CHARACTERISTICS - One exemplary embodiment includes a fuel cell comprising a polymer electrolyte membrane sandwiched between an anode and a cathode, a gas diffusion layer disposed over each of the cathode and the anode, a gas flow distributor layer disposed over the gas diffusion layer on both the anode and cathode sides, and optionally a coolant plate disposed over the gas flow distributor layer. The thermal resistance of the combined gas diffusion layer and gas flow distributor layer on the anode and/or cathode side is sufficient to allow the cathode catalyst layer to operate at an elevated temperature to effectively evaporate water produced at the cathode. | 02-02-2012 |
Jeffrey L. Brodsky, Pittsburgh, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110160160 | METHODS FOR HEAT SHOCK PROTEIN DEPENDENT CANCER TREATMENT - The present invention provides a method of treating an Hsp70 dependent cancer, including: providing at least one Hsp70 dependent cancer cell; contacting the at least one cell with a sub-effective concentration of a dihydropyrimidinone compound; and contacting the at least one cell with a sub-effective concentration of a proteasome inhibitor, wherein the sub-effective concentration of the dihydropyrimidinone compound and the sub-effective concentration of the proteasome inhibitor have a synergistic effect upon the at least one cell. | 06-30-2011 |
Jonathan S. Brodsky, Richardson, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100169064 | SYSTEM, AN APPARATUS AND A METHOD FOR PERFORMING CHIP-LEVEL ELECTROSTATIC DISCHARGE SIMULATIONS - A modeler for components of an IC under ESD conditions, a method of simulating ESD behavior of an IC and an ESD simulation system. In one embodiment, the modeler includes: (1) a circuit analyzer configured to provide identified ESD cells and circuitry of the IC by comparing component information of the IC with predefined ESD protection elements and predefined circuit topologies and (2) a model generator configured to create linearized models of the identified ESD cells and the identified circuitry based on physical attributes associated with the identified ESD cells and the identified circuitry, wherein a combination of the linearized models represent operation of the IC component under ESD conditions. | 07-01-2010 |
| 20100169845 | METHOD OF OPTIMIZING ESD PROTECTION FOR AN IC, AN ESD PROTECTION OPTIMIZER AND AN ESD PROTECTION OPTIMIZATION SYSTEM - An ESD protection optimizer, a method of optimizing ESD protection for an IC and an ESD protection optimization system is disclosed. In one embodiment, the ESD protection optimizer includes: (1) a circuit analyzer configured to identify ESD cells and circuitry of the IC by comparing component information of the IC with predefined ESD protection elements and predefined circuit topologies and (2) an ESD resistance determiner configured to calculate a resistance value to couple in series with the circuitry, the resistance value based on protection cell physical attributes associated with the identified ESD cells and circuitry physical attributes associated with the identified circuitry. | 07-01-2010 |
| 20100169854 | ESD PROTECTION VALIDATOR, AN ESD VALIDATION SYSTEM AND A METHOD OF VALIDATING ESD PROTECTION FOR AN IC - Disclosed is an electrostatic discharge (ESD) protection validator, a method of validating ESD protection for an IC and an ESD validation system. In one embodiment, the ESD protection validator includes: (1) a circuit analyzer configured to compare component information of the IC with predefined ESD protection elements to identify ESD cells of the IC and (2) an ESD cell verifier configured to compare physical attributes associated with the identified ESD cells to ESD protection requirements and determine compliance therewith. | 07-01-2010 |
Jonathan S. Brodsky, Plano, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20080296669 | SYSTEM AND METHOD FOR MAKING A LDMOS DEVICE WITH ELECTROSTATIC DISCHARGE PROTECTION - A semiconductor device includes one or more LDMOS transistors and one of more SCR-LDMOS transistors. Each LDMOS transistor includes a LDMOS well of a first conductivity type, a LDMOS source region of a second conductivity type formed in the LDMOS well, and a LDMOS drain region of a second conductivity type separated from the LDMOS well by a LDMOS drift region of the second conductivity type. Each SCR-LDMOS transistor comprising a SCR-LDMOS well of the first conductivity type, a SCR-LDMOS source region of the second conductivity type formed in the SCR-LDMOS well, a SCR-LDMOS drain region of a second conductivity type, and a anode region of the first conductivity type between the SCR-LDMOS drain region and the SCR-LDMOS drift region. The anode region is separated from the SCR-LDMOS well by a SCR-LDMOS drift region of the second conductivity type. | 12-04-2008 |
Jonathan Scott Brodsky, Richardson, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100123985 | Driver With Electrostatic Discharge Protection - Various apparatuses, methods and systems for protecting a driver from electrostatic discharge are disclosed herein. For example, some exemplary embodiments provide a driver, including a buffer, a leakage path blocking transistor connected to an output of the buffer, and an output driver connected to an output of the leakage path blocking transistor. Current from the output driver to the buffer is substantially blocked by the leakage path blocking transistor. | 05-20-2010 |
Micah Brodsky, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100229157 | EXTRACTING AND COLLECTING PLATFORM USE DATA - A system for reporting information about how selected components of an operating system are used by applications on a computing device. A manifest of components is provided from a management server to a computing device. The manifest specifies components of the operating system for which usage information is to be collected. The computing device surveys applications for calls to the components specified in the manifest. Surveys may be performed by static scanning and/or dynamic monitoring. In static scanning, application files are scanned for keyword strings specified in the manifest. Keyword string matches are recorded to a log file. In dynamic monitoring, calls from executing applications to components specified by the manifest are identified and logged. A report is generated from the log and sent to the management server. The management server then aggregates and analyzes reports from multiple computing devices to enable developers to assess how the components are being used. | 09-09-2010 |
Michael Brodsky, Brookline, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090076394 | High-frequency tissue imaging devices and methods - The present invention relates to systems and methods for signal processing of an ultrasound images. More specifically, a preferred embodiment of an ultrasound imaging system includes a transducer array that provides imaging signals at a first frequency, f | 03-19-2009 |
| 20120029357 | ULTRASOUND 3D IMAGING SYSTEM - The present invention relates to an ultrasound imaging system in which the scan head either includes a beamformer circuit that performs far field subarray beamforming or includes a sparse array selecting circuit that actuates selected elements. When used with second stage beamforming system, three dimensional ultrasound images can be generated. | 02-02-2012 |
Michael Brodsky, Millburn, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20120016634 | Characterization of Single-Photon Detectors Using a Source of Photon Pairs - Operational parameters of a single-photon detector are determined with a source of photon pairs. At a fixed trigger, a dark count probability and a series of count probabilities at different optical powers are determined. A particular optical power is selected by adjusting the optical power of the source of photon pairs. The dark count probability and the count probabilities are determined for different trigger rates. The operational parameters include efficiency, afterpulsing constant, and detrap time. The operational parameters are computed by fitting the computed dark count probabilities and count probabilities to a user-defined relationship. | 01-19-2012 |
| 20120016635 | Characterization of Single-Photon Detectors Using a Continuous Wave Laser Source - Operational parameters of a single-photon detector are determined with a continuous wave laser source. At a fixed trigger, a dark count probability and a series of count probabilities at different optical powers are determined. A particular optical power is selected by using a wide-range variable attenuator to attenuate the optical power of the continuous wave laser. The dark count probability and the count probabilities are determined for different trigger rates. The operational parameters include efficiency, afterpulsing constant, and detrap time. The operational parameters are computed by fitting the computed dark count probabilities and count probabilities to a user-defined relationship. | 01-19-2012 |
| 20120063596 | Characterization of an Entangled Photon System - A quantum key distribution system comprises a source of entangled photon pairs and two single-photon detectors. The source is coupled to each of the single-photon detectors by optical fiber. Operational systems parameters include the efficiency of the first single-photon detector, the efficiency of the second single-photon detector, and the maximum average number of photon pairs per unit time generated by the source. To characterize the operational systems parameters, the transmittances between the source and each single-photon detector are determined. The dark count probability of the first single-photon detector and the dark count probability of the second single-photon detector are determined. The count probability at the first single-photon detector, the count probability at the second single-photon detector, and the coincidence count probability are determined as a function of the optical power from the source. By fitting the values to a set of relationships, the operational systems parameters are computed. | 03-15-2012 |
| 20120063769 | Bandwidth Provisioning for an Entangled Photon System - A quantum key distribution system is deployed in an optical fiber network transporting classical data traffic. A source of entangled photon pairs is used to generate quantum keys. Classical data traffic is typically transported over channels in the C-band. If a pair of channels for transport of quantum data is available within the C-band, then the source of entangled photon pairs is tuned to emit in a pair of channels in the C-band. If a pair of channels for transport of quantum data is not available within the C-band, then the source of entangled photon pairs is tuned to emit in a pair of channels in a combined S-band and L-band. When a periodically-poled lithium niobate waveguide pumped with a laser is used for the source of entangled photon pairs, the output spectral properties are tuned by varying the temperature of the waveguide. | 03-15-2012 |
| 20120321301 | Bandwidth Provisioning for the Entangled Photon System by Adjusting the Phase Matching - A quantum key distribution system is deployed in an optical fiber network transporting classical data traffic. A source of entangled photon pairs is used to generate quantum keys. Classical data traffic is typically transported over channels in the C-band. If a pair of channels for transport of quantum data is available within the C-band, then the source of entangled photon pairs is tuned to emit in a pair of channels in the C-band. If a pair of channels for transport of quantum data is not available within the C-band, then the source of entangled photon pairs is tuned to emit in a pair of channels in a combined S-band and L-band. When a periodically-poled lithium niobate waveguide pumped with a laser is used for the source of entangled photon pairs, the output spectral properties are tuned by varying the temperature of the waveguide. | 12-20-2012 |
Michael A. Brodsky, Hillsboro, NH US
| Patent application number | Description | Published |
|---|---|---|
| 20080262476 | Powered Surgical System - A system for treating tissue includes a device including a first member and a second member arranged to move relative to the first member to treat tissue. The system also includes a processor configured to automatically control movement of the second member relative to the first member using position control methodology. A method of treating tissue includes providing a device having a first member and a second member arranged to move relative to the first member, moving the second member relative to the first member, and automatically controlling the movement of the second member using position control methodology. | 10-23-2008 |
Mikhail Brodsky, Milbourn, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100134788 | Method for Increasing Accuracy of Measurement of Mean Polarization Mode Dispersion - The present invention provides a method of determining a mean differential group delay associated with a length of optical fiber. The method including measuring a magnitude of a polarization mode dispersion vector as a function of frequency, using a frequency-domain polarization mode dispersion measurement apparatus, where the magnitude of the polarization mode dispersion vector is a scalar differential group delay. Also the method calculates a frequency derivative of the scalar differential group delay from the magnitude of the polarization mode dispersion vector to obtain a first result. The frequency derivative of the scalar differential group delay being a scalar second-order polarization mode dispersion function. The method further multiplies a proportionality coefficient B | 06-03-2010 |
| 20110051126 | Method for Increasing Accuracy of Measurement of Mean Polarization Mode Dispersion - A method of determining a mean square differential group delay associated with a length of optical fiber. The method including measuring a polarization mode dispersion vector as a function of frequency, using a frequency-domain polarization mode dispersion measurement apparatus. The method also including calculating a second-order polarization mode dispersion vector as a function of frequency by calculating a derivative of the polarization mode dispersion vector with respect to frequency. Also, calculating the mean of the magnitude of the second-order polarization mode dispersion vector to obtain a first result. Further, multiplying a proportionality coefficient by the first result to calculate the mean square differential group delay. | 03-03-2011 |
Philip Brodsky, Redmond, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20110306414 | RIVET MECHANISMS - A method and apparatus that utilizes techniques for modifying the game space of a video game displayed on a display screen by inserting structural elements which become part of the game space and can interact with various game characters. | 12-15-2011 |
Robert A. Brodsky, Brooklandville, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20110092462 | USE OF HIGH-DOSE OXAZAPHOSPHORINE DRUGS FOR TREATING IMMUNE DISORDERS - This disclosure relates, at least in part, to methods of eliminating adverse immune reactions in a subject in need thereof including those associated with autoimmune diseases, allergic reactions and transplant rejection, including administration of a lymphocytotoxic non-myeloablative amount of a oxazaphosphorine drug to the subject. | 04-21-2011 |
| 20120100162 | Cyclophosphamide in Combination with Immune Therapeutics - The present invention relates to methods of treating a cancer and in particular, a B-cell derived cancer, using a lymphocytotoxic but hematopoeitic cell sparing high-dose pulsed amount of an oxazaphosphorine drug, either alone, or in combination with immune therapeutics such as, for example, monoclonal antibodies that selectively bind B-cell specific antigens. | 04-26-2012 |
| 20120128685 | USE OF HIGH-DOSE OXAZAPHOSPHORINE DRUGS IN COMBINATION WITH MONOCLONAL ANTIBODIES FOR TREATING IMMUNE DISORDERS - The present invention relates to methods of treating an autoimmune disorder, using a lymphocytotoxic but hematopoeitic cell sparing high-dose pulsed amount of an oxazaphosphorine drug in combination with immune therapeutics such as, for example, monoclonal antibodies that selectively bind B-cell specific antigens. | 05-24-2012 |
| 20120129206 | METHOD OF IDENTIFYING PATIENTS SUITABLE FOR HIGH-DOSE CYCLOPHOSPHAMIDE TREATMENT - The present invention provides methods of identifying subjects that are suitable for high-dose cyclophosphamide treatment. | 05-24-2012 |
| 20120148577 | USE OF HIGH-DOSE, POST-TRANSPLANTATION OXAZAPHOSPHORINE DRUGS FOR REDUCTION OF TRANSPLANT REJECTION - A lymphocytotoxic, but hematopoietic stem cell-sparing, high-dose amount of an oxazaphosphorine drug such as, for example, cyclophosphamide, administered post-transplantation can be used to reduce transplant rejection, including graft-versus-host-disease (GVHD). In some embodiments, the transplants are bone marrow transplants or hematopoietic stem cell transplants carried out for the treatment of hematologic disorders, including hematologic malignancies and non-malignant hematologic disorders. In some embodiments, the transplants are carried out for the treatment of hereditary hemoglobinopathies, such as sickle cell anemia and thalassemia. | 06-14-2012 |
| 20120148611 | Cyclophosphamide in Combination with Anti-Idiotypic Vaccines - The present invention relates to methods of treating a cancer and in particular, a B-cell derived cancer, using a lymphocytotoxic but hematopoeitic cell sparing high-dose pulsed amount of an oxazaphosphorine drug in combination with immune therapeutics such as, for example, an autologous idiotypic vaccine and monoclonal antibodies that selectively bind B-cell specific antigens. | 06-14-2012 |
William Brodsky, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20100191669 | Method and System for Creating and Trading Derivative Investment Instruments Based on an Index of Investment Management Companies - A method and system for creating a stock index for a group of investment management companies is disclosed. The method may include obtaining first trade information for each security representative of the group of investment management companies during a first time period, aggregating the first trade information for a predetermined time period, storing the aggregated first trade information, calculating from the aggregated first trade information an index for the group of investment management companies, determining a standardized measure of the index based on the aggregated first trade information obtained in the first time period, and periodically recalculating the index based on second trade information for each security representative of the group of investment management companies during a second time period. | 07-29-2010 |
| 20120066150 | Method and System for Creating and Trading Derivative Investment Instruments Based on an Index of Investment Management Companies - A method and system for creating a stock index for a group of investment management companies is disclosed. The method may include obtaining first trade information for each security representative of the group of investment management companies during a first time period, aggregating the first trade information for a predetermined time period, storing the aggregated first trade information, calculating from the aggregated first trade information an index for the group of investment management companies, determining a standardized measure of the index based on the aggregated first trade information obtained in the first time period, and periodically recalculating the index based on second trade information for each security representative of the group of investment management companies during a second time period. | 03-15-2012 |