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Breslin, PA

David Breslin, Telford, PA US

Patent application numberDescriptionPublished
20090318560FORMULATIONS FOR CATHEPSIN K INHIBITORS - The instant invention relates to pharmaceutical compositions comprising cathepsin K inhibitors as the active ingredient with excipients which include binders, diluents, lubricants, and disintegrants. Also disclosed are processes for making said pharmaceutical compositions for oral and intravenous delivery.12-24-2009
201001446954-AZETIDINYL-1-HETEROARYL-CYCLOHEXANOL ANTAGONISTS OF CCR2 - The present invention comprises compounds of Formula (I).06-10-2010

Henry Breslin, Lansdale, PA US

Patent application numberDescriptionPublished
20110105455PHENOXY-SUBSTITUTED PYRIMIDINES AS OPIOID RECEPTOR MODULATORS - Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows:05-05-2011

Henry J. Breslin, Lansdale, PA US

Patent application numberDescriptionPublished
20100324051NOVEL COMPOUNDS AS OPIOID RECEPTOR MODULATORS - The present invention is directed to novel opioid receptor modulators of Formula (I).12-23-2010

Patent applications by Henry J. Breslin, Lansdale, PA US

Henry Joseph Breslin, Lansdale, PA US

Patent application numberDescriptionPublished
20080255191BENZYLIMIDAZOLYL SUBSTITUTED 2-QUINOLINE AND QUINAZOLINE DERIVATIVES FOR USE AS FARNESYL TRANSFERASE INHIBITORS - This invention comprises the novel compounds of formula (I)10-16-2008
20090221555FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND c-MET INHIBITORS - The present invention provides a compound of formula I or II or a pharmaceutically acceptable salt form thereof, wherein R09-03-2009

Patent applications by Henry Joseph Breslin, Lansdale, PA US

Michael J. Breslin, Drexel Hili, PA US

Patent application numberDescriptionPublished
20100168134PYRIDYL PIPERIDINE OREXIN RECEPTOR ANTAGONISTS - The present invention is. directed to pyridyl piperidine compounds of formula (I) which are antagonists of orexin receptors, and which are useful' in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.07-01-2010

Michael J. Breslin, Drexel Hill, PA US

Patent application numberDescriptionPublished
20090176789Diazaspirodecane orexin receptor antagonists - The present invention is directed to diazaspirodecane compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.07-09-2009
20090192143Substituted diazepan orexin receptor antagonists - The present invention is directed to substituted diazepan compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.07-30-2009
201000297362-SUBSTITUTED PROLINE BIS-AMIDE OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to 2-substituted proline bis-amide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.02-04-2010
20110195957SUBSTITUTED DIAZEPAN OREXIN RECEPTOR ANTAGONISTS - The present invention is directed to substituted diazepan compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.08-11-2011

Patent applications by Michael J. Breslin, Drexel Hill, PA US

Michael J. Breslin, Harleysville, PA US

Patent application numberDescriptionPublished
201102016322,5-Disubstituted Piperidine Orexin Rceptor Antagonists - The present invention is directed to 2,5-disubstituted piperidine amide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.08-18-2011