Breiner
Boris Breiner, Cambridge GB
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20150056618 | METHOD AND APPARATUS - A method for mapping the number and location of restriction enzymes sites for a given restriction enzyme in a target nucleic acid comprises the steps of (1) translocating a target nucleic acid having detectable elements characteristic of the presence of the restriction enzyme sites therein through an analysing device comprising a nanopore and a detection window and (2) causing the detectable elements to be detected as they pass though the detection window. Typically the detectable elements are formed by attaching to the restriction enzyme sites a restriction enzyme to which one or more marker moieties have been added. The data or signal obtained from the detection is suitably in the form of a distribution profile of the detectable elements, and therefore the restriction enzyme sites along the length of the target nucleic acid and can be used to create a reference set of like distribution profiles against which new distributions can be compared. When the target nucleic acid is for example double stranded human DNA such comparisons enable valuable insights to be drawn about an individual's identity or his or her susceptibility to certain health conditions. | 02-26-2015 |
20150232925 | SEQUENCING METHOD - Disclosed is a method for determining the sequence of nucleotide bases in a polynucleotide analyte characterised by the steps of: | 08-20-2015 |
20150247192 | SEQUENCING METHOD - Disclosed is a method for sequencing a polynucleotide analyte comprising:•a. generating a stream of droplets containing a single nucleotide wherein the order of single nucleotides in the droplet stream corresponds to the sequence of nucleotides in the analyte;•b. introducing into each droplet a plurality of biological probe types each type comprising a different label in an undetectable state and being adapted to capture a different single nucleotide;•c. causing the single nucleotide contained in the droplet to bind to its complementary probe and•d. causing the label to be released from the probe that has bound the nucleotide in a detectable state. The probe is a dumbbell shaped probe comprising fluorescent donor and quencher labels and a single nucleotide gap. After gap repair by a polymerase and a ligase, a restriction enzyme recognition site is cleaved by a restriction enzyme, followed by exonuclease digestion to release the labels. | 09-03-2015 |
20150275293 | BIOLOGICAL PROBES AND THE USE THEREOF - Disclosed is a biological probe characterised in that it comprises a single-stranded nucleotide region the ends of which are attached to two different oligonucleotide regions wherein at least one of the oligonucleotide regions comprises detectable elements having a characteristic detection property and wherein the detectable elements are so arranged on the oligonucleotide region that the detectable property is less detectable than when the same number detectable elements are bound to a corresponding number of single nucleotides. The biological probe is especially useful for capturing single nucleotides or single-stranded nucleotides to create a used probe which can be degraded by means of a restriction enzyme and an exonuclease to generate single nucleotides carrying a detectable element in a form which can be detected. Typically the detectable elements are fluorophores and the corresponding characteristic fluorescence is rendered undetectable in the probe by for example the use of multiple adjacent fluorophores or mixtures of fluorophores and quenchers attached thereto. Preferably the single stranded nucleotide region is comprised of a single nucleotide whose associated nucleotide base is one of the characteristic of the nucleotides bases found in DNA or RNA. | 10-01-2015 |
Boris Breiner, Cambridgeshire GB
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20160040223 | SINGLE NUCLEOTIDE DETECTION METHOD - A method for determining the sequence of nucleotide bases in a polynucleotide analyte is provided. It is characterised by the steps of (1) generating a stream of single nucleotide bases from the analyte; (2) producing captured molecules by reacting each single nucleotide base with a capture system; (3) amplifying at least part of the captured molecule to produce a plurality of amplicons characteristic of the single nucleotide base; (4) labelling the amplicons with a corresponding probe having a characteristic detectable element and (5) detecting a property characteristic of the detectable element. | 02-11-2016 |
20160040224 | SINGLE NUCLEOTIDE DETECTION METHOD - A method for determining the sequence of nucleotide bases in a polynucleotide analyte is provided. It is characterised by the steps of (1) generating a stream of single nucleotide bases from the analyte by pyrophosphorolysis; (2) producing captured molecules by reacting each single nucleotide base with a capture system labelled with detectable elements in an undetectable state; (3) releasing the detectable elements from each captured molecule in a detectable state and (4) detecting the detectable elements so released and determining the sequence of nucleotide bases therefrom. The method can be used advantageously in sequencers involving the use of microdroplets. | 02-11-2016 |
David E. Breiner, Glastonbury, CT US
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20110187064 | Hose or cable release alert system - An alerting system for signaling the displacement of a leading end portion of a hose or the like, carried by a vehicle, includes a hose-gripping unit, a visible or audible signal generator, and a mounting box for connecting the gripping unit to support structure. Displacement of the hose from the gripping unit may generate an alarm signal to enable the operator to immediately bring the vehicle to a stop, or it may generate a signal simply to indicate when one of several hoses has been intentionally deployed. | 08-04-2011 |
20130300553 | Hose or cable release alert system - An alerting system for signaling the displacement of a leading end portion of a hose or the like, carried by a vehicle, includes a hose-gripping unit, a visible or audible signal generator, and a mounting box for connecting the gripping unit to support structure. Displacement of the hose from the gripping unit may generate an alarm signal to enable the operator to immediately bring the vehicle to a stop, or it may generate a signal simply to indicate when one of several hoses has been intentionally deployed. | 11-14-2013 |
Jacob Breiner, Kvistgaard DK
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20140234744 | STACK ASSEMBLY - A solid oxide fuel or solid oxide electrolysis cell Stack assembly ( | 08-21-2014 |
Lyle D. Breiner, Meridian, ID US
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20100282164 | METHODS AND SYSTEMS FOR CONTROLLING TEMPERATURE DURING MICROFEATURE WORKPIECE PROCESSING, E.G., CVD DEPOSITION - The present disclosure provides methods and systems for controlling temperature. The method has particular utility in connection with controlling temperature in a deposition process, e.g., in depositing a heat-reflective material via CVD. One exemplary embodiment provides a method that involves monitoring a first temperature outside the deposition chamber and a second temperature inside the deposition chamber. An internal temperature in the deposition chamber can be increased in accordance with a ramp profile by (a) comparing a control temperature to a target temperature, and (b) selectively delivering heat to the deposition chamber in response to a result of the comparison. The target temperature may be determined in accordance with the ramp profile, but the control temperature in one implementation alternates between the first temperature and the second temperature. | 11-11-2010 |
20110163416 | METHODS FOR FORMING SMALL-SCALE CAPACITOR STRUCTURES - The present disclosure provides small scale capacitors (e.g., DRAM capacitors) and methods of forming such capacitors. One exemplary implementation provides a method of fabricating a capacitor that includes sequentially forming a first electrode, a dielectric layer, and a second electrode. At least one of the electrodes may be formed by a) reacting two precursors to deposit a first conductive layer at a first deposition rate, and b) depositing a second conductive layer at a second, lower deposition rate by depositing a precursor layer of one precursor at least one monolayer thick and exposing that precursor layer to another precursor to form a nanolayer reaction product. The second conductive layer may be in contact with the dielectric layer and have a thickness of no greater than about 50 Å. | 07-07-2011 |
20130166057 | METHODS FOR FORMING SMALL-SCALE CAPACITOR STRUCTURES - The present disclosure provides small scale capacitors (e.g., DRAM capacitors) and methods of forming such capacitors. One exemplary implementation provides a method of fabricating a capacitor that includes sequentially forming a first electrode, a dielectric layer, and a second electrode. At least one of the electrodes may be formed by a) reacting two precursors to deposit a first conductive layer at a first deposition rate, and b) depositing a second conductive layer at a second, lower deposition rate by depositing a precursor layer of one precursor at least one monolayer thick and exposing that precursor layer to another precursor to form a nanolayer reaction product. The second conductive layer may be in contact with the dielectric layer and have a thickness of no greater than about 50 Å. | 06-27-2013 |
Oded Haim Breiner, Netanya IL
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20100057686 | Deep Web Search - A data processing system and a computer implemented method for searching registered websites including multimedia content according to a user query. The data processing system includes a mediator server with a database storing the multimedia content from the registered websites and an application configured to receive and apply the user's query to the database and provide search results at least one resolution. The computer implemented method includes: (i) receiving multimedia content of the registered websites and storing the content in a database, (ii) receiving and applying the user's query, and (iv) providing search results at least one resolution. | 03-04-2010 |
20150033219 | METHOD AND SYSTEM FOR DISPLAYING A NON-INSTALLED ANDROID APPLICATION AND FOR REQUESTING AN ACTION FROM A NON-INSTALLED ANDROID APPLICATION - A method of operating an Android appliance in which code of a calling application is operative to send an Android operating system or other application an Intent object. The Intent object encapsulates a “Activity Action” string and optional auxiliary data relating to the Intent object. The user is presented with a user interface of comprising not currently installed applications capable of handling the Intent. Upon user selection of an application not currently installed on the Android appliance, the selected application is installed on the Android appliance. Subsequently the matching activity in the installed application is launched. Afterwards the Intent is passed to the Activity, capable of handling the aforementioned Intent, in the now launched application. | 01-29-2015 |
Scott Breiner, Dubuque, IA US
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20090095603 | KEYLESS IGNITION - An engine start system for use with a ground engaging vehicle, the system including an input device, a processing circuit, a display and an engine controller unit. The input device produces a signal when depressed, the signal initiates the application of electrical power to the engine start system. The processing circuit is activated by the application of electrical power thereto. The display is communicatively coupled with the processing circuit. The input device produces another signal when depressed. The other signal is detected by the processing circuit and the processing circuit, in response to the other signal, sends either a PIN request notice to the display or a start signal to the engine controller unit. | 04-16-2009 |
Scott J Breiner, Dubuque, IA US
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20130286671 | ADAPTIVE WORK LIGHT AND DRIVE LIGHT INTENSITY FOR A WORK VEHICLE - A vehicle lighting system in which a controller changes the intensity of a drive light and/or a work light as a function of a speed of the vehicle. | 10-31-2013 |
20140273785 | WORK VEHICLE HVAC CONTROL BASED ON OPERATOR SEAT DIRECTION - An HVAC control system for directing the flow of air in a work vehicle's HVAC system responds to the orientation of a rotating seat within the work vehicle's cabin. The seat may rotate between at least two operational positions, such that the operator of the work vehicle may control a forward or a rearward implement. The HVAC control system includes one or more detectors for detecting the position of the seat. A control module receives output from the detectors and allows or prevents the flow of air through particular ducts in the HVAC system based on the seat's position. The control module may actuate one or more doors to open and close ducts as needed. The control module may operate a first door to open or close forward ducts and a second door to open or close rearward ducts depending on whether the seat is facing forward or rearward. | 09-18-2014 |
Scott Joseph Breiner, Dubuque, IA US
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20090313860 | AUTOMATIC DEPTH CORRECTION BASED ON BLADE PITCH - A vehicle is disclosed that is configured to automatically maintain a depth of the blade during pitching of the blade. A method for utilizing the same is also disclosed. | 12-24-2009 |
Sheldon Breiner, Portola Valley, CA US
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20100134266 | Vehicular system having a warning system to alert motorists that a mobile phone is in use - This invention relates to a warning system for use on board a motorized road vehicle. The warning system includes an activity detector that detects an RF signal emitted from a mobile phone when a person driving the motorized vehicle is communicating over the mobile phone. The warning system also has a display device in communication with the activity detector, the display device providing a visual indication to a motorist of another vehicle near the motorized vehicle in traffic, in a manner that allows the motorist of the other vehicle to ascertain when the person driving the motorized vehicle is using the mobile phone. | 06-03-2010 |