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Brassart

Dominique Brassart, Chavannes/renens CH

Patent application numberDescriptionPublished
20100196340LACTID ACID BACTERIA AS PRIOBIOTIC STRAINS AND COMPOSITIONS CONTAINING SAME - Useful probiotics have been selected among lactic acid bacteria strains of the genus 08-05-2010

Dominique Brassart, Chavannes-Pres-Renes CH

Patent application numberDescriptionPublished
20110223136NUTRITIONAL SUPPORT TO PREVENT AND/OR MITIGATE BONE MARROW TOXICITY FROM A CANCEROUS TUMOR - The present invention relates to methods and immunonutritional compositions for preventing or mitigating paralysis of the bone marrow, caused by a tumor or neoplasm, between cycles of and after anti-cancer therapy, thereby attaining a better efficacy of the treatment. More particularly, the present invention relates to methods and immunonutritional compositions that can transiently preventing or moderating, bone marrow paralysis or neutropenia of a subject tumor-induced apoptosis or necrosis or other cell damage such that the innate and adaptive immune functions and normal physiology of the bone marrow are preserved, at least in part, which, in turn, lead to (i) a better tolerance and increased efficacy to treatment; (ii) transient augmentation or enhancement of immunocompetence of the immune cell; and (iii) optimization of the effects of and increase of immunocompetence of the immune cell weakened due to paralysis of the bone marrow, caused by a tumor or neoplasm.09-15-2011
20110229521NUTRITIONAL SUPPORT OF THE IMMUNE SYSTEM DURING ANTI-CANCER TREATMENT - The present invention relates to methods and immunonutritional compositions for preventing the impairment of the immune function during anti-cancer therapy, thereby attaining a better efficacy of the treatment. More particularly, the present invention relates to methods and immunonutritional compositions that can transiently augment or enhance the immunocompetence of an immune cell and the immunogenecity of a tumor cell of a subject undergoing anti-cancer therapy-induced apoptosis and tumor-cell-enhanced immunogenicity such that the innate and adaptive immune functions and normal physiology of the immune cell are preserved, which, in turn, lead to (i) a better tolerance and increased efficacy to anti-cancer therapy; (ii) transient augmentation or enhancement of immunocompetence of the immune cell and immunogenecity of the tumor cell; and (iii) optimization of the effects of and increase of immunocompetence of the immune cell weakened by anti-cancer therapy.09-22-2011

Dominique Brassart, Chavannes-Ptes-Renes CH

Patent application numberDescriptionPublished
20110229447NUTRITIONAL SUPPORT TO PREVENT OR MODERATE BONE MARROW PARALYSIS OR NEUTROPENIA DURING ANTI-CANCER TREATMENT - The present invention relates to methods and immunonutritional compositions for preventing the impairment of the immune function during anti-cancer therapy, thereby attaining a better efficacy of the treatment. More particularly, the present invention relates to methods and immunonutritional compositions that can transiently preventing or moderating, bone marrow paralysis or neutropenia of a subject undergoing anti-cancer therapy-induced apoptosis or necrosis or other cell damage such that the innate and adaptive immune functions and normal physiology of the bone marrow are preserved, at least in part, which, in turn, lead to (i) a better tolerance and increased efficacy to anti-cancer therapy; (ii) transient augmentation or enhancement of immunocompetence of the immune cell; and (iii) optimization of the effects of and increase of immunocompetence of the immune cell weakened by anti-cancer therapy.09-22-2011

Sylvie Anne Yvonne Brassart, Reims FR

Patent application numberDescriptionPublished
20090305955Cyclopeptide with Anti-Cancer Activity Derived from Collagen Type IV - The present invention relates to a cyclopeptide characterized in that it comprises the YSNS amino acid sequence, and more particularly a cyclopentapeptide which forms a β-bend structure at the YSNS amino acids. In one specific embodiment, the cyclopeptide of the invention is capable of binding to the αVβ3-integrin. The application also claims the use of a cyclopeptide of the invention in the treatment of cancer, and more particularly in the treatment of the various forms of melanoma, and also in the manufacture of a medicament for treating cancer. Finally, the application describes the use of a cyclopeptide of the invention for inhibiting or reducing angiogenesis, and more particularly in tumours, and also in the manufacture of a medicament for inhibiting or reducing angiogenesis.12-10-2009