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Brasel

Kenneth Brasel, Seattle, WA US

Patent application numberDescriptionPublished
20080219985PROK2 ANTAGONISTS AND METHODS OF USE - The present invention provides methods of using PROK2 and PROK1 antagonist, including monoclonal antibodies to treat inflammation, angiogenesis, and cancer.09-11-2008
20090075886Dendritic cell stimulatory factor - Flt3-ligand can be used to generate large numbers of dendritic cells from hematopoietic progenitor and stem cells. Flt3-ligand can be used to augment immune responses in vivo, and expand dendritic cells ex vivo. Such dendritic cells can then be used to present tumor, viral or other antigens to naive T cells, can be useful as vaccine adjuvants.03-19-2009

Kenneth A. Brasel, Seattle, WA US

Patent application numberDescriptionPublished
20110189082HUMAN GM-CSF ANTIGEN BINDING PROTEINS - Antigen binding proteins that bind to human GM-CSF protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of GM-CSF to GM-CSFR, inhibit GM-CSF-induced proliferation and signaling of myeloid lineage cell lines and inhibit GM-CSF-induced activation of human monocytes.08-04-2011

Kenneth Allan Brasel, Seattle, WA US

Patent application numberDescriptionPublished
20090155164HUMAN C-FMS ANTIGEN BINDING PROTEINS - Antigen binding proteins that bind to human c-fms protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of c-fms to CSF-1, reduce monocyte migration into tumors, and reduce the accumulation of tumor-associated macrophages.06-18-2009

Timothy C. Brasel, Newark, DE US

Patent application numberDescriptionPublished
20090057961PROCESS FOR PRODUCING CLEAR POLYPROPYLENE BASED STRETCH BLOW MOLDED CONTAINERS WITH IMPROVED INFRARED HEAT-UP RATES - A process for producing clear injection stretch blow molded containers comprising: 03-05-2009