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Brandon Seal

Brandon Seal, West Lafayette, IN US

Patent application numberDescriptionPublished
20090149389Kinase Inhibitors And Uses Thereof - The present invention relates to kinase inhibiting compositions and uses thereof. The invention further provides isolated kinase inhibiting peptides and uses thereof for inhibiting hyperplasia, for inhibiting the growth of neoplasms, and for inducing programmed cell death in a cell population.06-11-2009
20100158968CELL-PERMEANT PEPTIDE-BASED INHIBITOR OF KINASES - The described invention provides kinase inhibiting compositions containing a therapeutic amount of a therapeutic inhibitor peptide that inhibits at least one kinase enzyme, methods for treating an inflammatory disorder whose pathophysiology comprises inflammatory cytokine expression, and methods for treating an inflammatory disorder whose pathophysiology comprises inflammatory cytokine expression using the kinase inhibiting compositions.06-24-2010

Brandon Seal, Mesa, AZ US

Patent application numberDescriptionPublished
20080293640Polypeptide inhibitors of HSP27 kinase and uses therefor - The present invention provides polypeptide inhibitors of HSP27 kinase, compositions thereof, and methods for using such polypeptides and compositions for various therapeutic uses.11-27-2008
20090176694Reagents and Methods for Smooth Muscle Therapies - The present invention provides novel polypeptides comprising heat shock protein 20 (HSP20)-derived polypeptides to treat or inhibit smooth muscle vasospasm, as well to treat and inhibit smooth muscle cell proliferation and migration.07-09-2009
20090176695Reagents and Methods for Smooth Muscle Therapies - The present invention provides novel polypeptides comprising heat shock protein 20 (HSP20)-derived polypeptides to treat or inhibit smooth muscle vasospasm, as well to treat and inhibit smooth muscle cell proliferation and migration.07-09-2009
20090258819Reagents and Methods for Smooth Muscle Therapies - The present invention provides novel polypeptides comprising heat shock protein 20 (HSP20)-derived polypeptides to treat or inhibit smooth muscle vasospasm, as well to treat and inhibit smooth muscle cell proliferation and migration.10-15-2009
20100004165Novel Protein Transduction Domains and Uses Therefor - The present invention provides novel transduction domains, compositions comprising such transduction domains, and their use for in vivo molecular delivery.01-07-2010

Patent applications by Brandon Seal, Mesa, AZ US

Brandon Seal, W. Lafayette, IN US

Patent application numberDescriptionPublished
20090196927Polypeptide Inhibitors of HSP27 Kinase and Uses Therefor - The present invention provides polypeptide inhibitors of HSP27 kinase, compositions thereof, and methods for using such polypeptides and compositions for various therapeutic uses.08-06-2009
20090269406Therapeutic uses of biocompatible biogel compositions - The present invention relates to biocompatible biogel compositions and methods of drug delivery. The biocompatible biogel is a physical polymer matrix formed via affinity interactions between its components. The components of the biocompatible biogel comprise a cationic component, an anionic component, and optionally a therapeutic agent.10-29-2009

Brandon Seal, Pleasant Grove, UT US

Patent application numberDescriptionPublished
20110288036Methods for Treating or Preventing Vascular Graft Failure - The described invention provides pharmaceutical compositions and methods for treating or preventing vascular graft failure in a subject in need of such treatment, the method comprising administering a therapeutically effective amount of a composition comprising a polypeptide of amino acid sequence YARAAARQARAKALARQLGVAA (SEQ ID NO: 1) or a functional equivalent thereof, and a pharmaceutically acceptable carrier. The methods also are clinically useful for treating a pre-atherosclerotic intimal hyperplasia condition.11-24-2011