Patent application number | Description | Published |
20090325927 | Benzofuro- and benzothienopyrimidine modulators of the histamine H4 receptor - Benzofuro- and benzothienopyrimidine compounds are described, which are useful as H | 12-31-2009 |
20110092474 | Diamino-pyridine, pyrimidine, and pyrazine modulators of the histamine H4 receptor - Diamino-pyridine, pyrimidine and pyridazine compounds which may be used as H | 04-21-2011 |
20110160451 | 2-Aminopyrimidine modulators of the histamine H4 receptor - 2-Aminopyrimidine compounds are described, which are useful as H | 06-30-2011 |
20110160452 | 2-Aminopyrimidine modulators of the histamine H4 receptor - 2-Aminopyrimidine compounds are described, which are useful as H | 06-30-2011 |
20110218338 | 2-AMINOPYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR - 2-Aminopyrimidine compounds are described, which are useful as H | 09-08-2011 |
20120202783 | FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS - Disubstituted 3,8-diaza-bicyclo[4.2.0]octane and 3,6-diazabicyclo[3.2.0]heptane compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia. | 08-09-2012 |
20120208812 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-c]PYRROLES AS OREXIN RECEPTOR MODULATORS - Disubstituted octahydropyrrolo[3,4-c]pyrrole compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia. | 08-16-2012 |
20130137672 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-c]PYRROLES AS OREXIN RECEPTOR MODULATORS - Certain disubstituted 3,8-diaza-bicyclo[4.2.0]octane and 3,6-diazabicyclo[3.2.0]heptane are described, which are useful as orexin inhibitors. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia. | 05-30-2013 |
20130158258 | 2-AMINOPYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR - 2-Aminopyrimidine compounds are described, which are useful as H | 06-20-2013 |
20130158259 | 2-AMINOPYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR - 2-Aminopyrimidine compounds are described, which are useful as H | 06-20-2013 |
20140171430 | DISUBSTITUTED OCTAHYDROPYRROLO [3,4-C] PYRROLES AS OREXIN RECEPTOR MODULATORS - Disubstituted octahydropyrrolo[3,4-c]pyrrole compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia. | 06-19-2014 |
20140179697 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-c]PYRROLES AS OREXIN RECEPTOR MODULATORS - Disubstituted octahydropyrrolo[3,4-c]pyrrole compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia. | 06-26-2014 |
20140275015 | P2X7 MODULATORS - The present invention is directed to compounds of Formulas (I, IIa and IIb): | 09-18-2014 |
20140275096 | P2X7 MODULATORS - The present invention is directed to a compound of Formula (I) | 09-18-2014 |
20140357614 | Diamino-Pyridine, Pyrimidine, and Pyrazine Modulators of the Histamine H4 Receptor - Diamino-pyridine, pyrimidine and pyridazine compounds which may be used as H | 12-04-2014 |