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Boulos

Boulos Asfour, Bonn DE

Patent application numberDescriptionPublished
20110071622INSTRUMENT FOR THE SURGICAL TREATMENT OF AORTIC VALVE DEFECTS - The invention relates to an instrument for the surgical treatment of aortic valve defects, in particular in young patients such as children, consisting of a shaft, a handle arranged at the proximal end of the shaft, and a leaflet body which is arranged at the distal end of the shaft and which has substantially the shape of the sinus of the aortic valve leaflet.03-24-2011

Boulos Zacharie, Quebec CA

Patent application numberDescriptionPublished
20100279959Medium-Chain Length Fatty Acids, Glycerides and Analogues as Neutrophil Survival and Activation Factors - A composition and method for promoting neutrophil survival and activation such as the treatment of neutropenia arising as an undesirable side effect of chemotherapy and radiation therapy. A composition containing medium-chain fatty acids, such as Capri acid or caprylic acid, or salts or triglycerides thereof, or mono- or diglycerides or other analogues thereof or medium-chain triglycerides (MCT) is administered to a human or animal needing treatment in an amount sufficient to reduce or eliminate neutropenia. The composition is administered in an amount effective to treat the disorder. The methods are also useful in the management of bone narrow transplantation and in the treatment of various neutropenic diseases.11-04-2010

Boulos Zacharie, Laval CA

Patent application numberDescriptionPublished
20090042768Purine derivatives and their use for treatment of autoimmune diseases - Compounds useful in the treatment of autoimmune disease are described by the following general formula:02-12-2009
200900681692,4,6-triamino-s-triazine-based compounds which bind to the tail (fc) portion of immunoglobulins and their use - The present invention describes new compounds which are useful for binding to the tail or Fc portion of immunoglobulins and so have utility in those applications which require the non-covalent binding interaction of a molecule with the Fc portion of immunoglobulins. Such applications include the detection and purification of immunoglobulins as well as the treatment of certain autoimmune diseases.03-12-2009
20090075867Triazine compounds and compositions thereof for the treatment of cancers - Compounds useful in the treatment of metastatic melanoma and other cancers containing a triazine ring scaffold are described. These compounds may be classified into two groups: (1) two disubstituted triazine rings are covalently linked by an organic linker to each other and (2) one trisubstituted triazine ring.03-19-2009
20100129350Triazine Derivatives, Compositions Containing Such Derivatives, and Methods of Treatment of Cancer and Autoimmune Diseases Using Such Derivatives - We describe compounds of the following general formula (I): wherein X is fluorine or chlorine; Y is oxygen, sulfur, or an amino group; R is an amino, hydroxyl, sulfonamide, or carboxamide group or an N-monomethyl or N-dimethyl analog thereof; m is an integer from 2 to 6, and n is an integer from 0 to 2. The compounds may be used for treating certain cancers and autoimmune diseases.05-27-2010

Patent applications by Boulos Zacharie, Laval CA