Borthwick
Alan David Borthwick, Stevenage GB
Patent application number | Description | Published |
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20090186867 | Substituted Diketopiperazines As Oxytocin Antagonists - A method of treating or preventing diseases or conditions mediated through the action of oxytocin which comprises administering to a human in need thereof of an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof. | 07-23-2009 |
20090247541 | Novel compounds - Compounds of formula (I) | 10-01-2009 |
20100305127 | NOVEL COMPOUNDS - Compounds of formula (I) | 12-02-2010 |
20110152262 | NOVEL COMPOUNDS - Compounds of formula (I) | 06-23-2011 |
20120202811 | NOVEL COMPOUNDS - Compounds of formula (I) | 08-09-2012 |
20130131338 | SUBSTITUTED DIKETOPIPERAZINES AS OXYTOCIN ANTAGONISTS - A method of treating or preventing diseases or conditions mediated through the action of oxytocin which comprises administering to a human in need thereof of an effective amount of a compound of the formula (I) or a pharmaceutically acceptable salt thereof. | 05-23-2013 |
20130253188 | NOVEL COMPOUNDS - Compounds of formula (I) | 09-26-2013 |
20140235639 | NOVEL COMPOUNDS - Compounds of formula (I) | 08-21-2014 |
Alan David Borthwick, London GB
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20120149737 | Therapeutic Aryl-Amido-Aryl Compounds and Their Use - The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl-amido-aryl compounds of the following formula (for convenience, collectively referred to herein as “AAA compounds”), which, inter alia, are (selective) retinoic acid receptor α (RARα) agonists. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to (selectively) activate RARα, and in the treatment of diseases and conditions that are mediated by RARα, that are ameliorated by the activation of RARα, etc., including cognitive disorders, memory impairment, memory deficit, senile dementia, Alzheimer's disease, early stage Alzheimer's disease, intermediate stage Alzheimer's disease, late stage Alzheimer's disease, cognitive impairment, and mild cognitive impairment. | 06-14-2012 |
Andrew Borthwick, Kirkland, WA US
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20120278263 | COST-SENSITIVE ALTERNATING DECISION TREES FOR RECORD LINKAGE - Record Linkage (RL) is the task of identifying two or more records referring to the same entity (e.g., a person, a company, etc.). RL models can be based on Cost Sensitive Alternating Decision Trees (ADTree), an algorithm that uniquely combines boosting and decision trees algorithms to create shorter and easier-to-interpret linking rules. These models can be naturally trained to operate at industrial precision/recall operating points, and the shorter output rules are so clear that it can effectively explain its decisions to non-technical users via score aggregation or visualization. The models significantly outperform other baselines on the desired industrial operating points, and the improved understanding of the model's decisions led to faster debugging and feature development cycles. | 11-01-2012 |
20130173560 | DYNAMIC RECORD BLOCKING - Dynamic blocking determines which pairs of records in a data set should be examined as potential duplicates. Records are grouped together into blocks by shared properties that are indicators of duplication. Blocks that are too large to be efficiently processed are further subdivided by other properties chosen in a data-driven way. We demonstrate the viability of this algorithm for large data sets. We have scaled this system up to work on billions of records on an 80 node Hadoop cluster. | 07-04-2013 |
Andrew Borthwick, Inverness GB
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20110006532 | ENERGY EXTRACTION APPARATUS AND METHOD - An apparatus and method for extracting energy from fluid motion comprising a deformable body adapted to be deformed by fluid motion, wherein the deformation of the deformable body is arranged to drive at least one energy medium to be delivered to an energy output; and wherein the energy medium is controllable in order to control at least one dynamic response of the deformable body. | 01-13-2011 |
David J Borthwick, Ipswich GB
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20080232350 | Computer-Telephony Integration - The invention provides a modification to the operation of the intelligent network instruction set whereby on transmitting an Initiate Call Attempt message between the SCP | 09-25-2008 |
James Borthwick, Sunnyvale, CA US
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20100052633 | MODIFIED CURRENT SOURCE (MCS) WITH SEAMLESS RANGE SWITCHING - A current source is provided with two resistor banks, and digital potentiometers are used to control how much each resistor bank affects the resulting output current. Furthermore, when the digital potentiometers are at a particular setting such that a particular resistor bank does not affect the resulting output current (i.e., the resistor bank is “inactive”), the resistance of that resistor bank can be switched without affecting the output current, thus minimizing or eliminating discontinuities in the output current during a current sweep operation. Thus, for example, when a resistor bank meets its threshold and becomes inactive, the resistance of the inactive resistor bank may be switched, and then the digital potentiometer setting may be changed to facilitate smoothly reactivating that resistor bank, with the new resistance. | 03-04-2010 |
James R. Borthwick, Vancouver CA
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20120114181 | VEHICLE POSE ESTIMATION AND LOAD PROFILING - A method of estimating the pose of a vehicle relative to a stereo camera is described herein. The method includes acquiring at least one stereo image of the vehicle from the stereo camera, wherein the stereo image comprises a plurality of scene data points, selecting a plurality of model data points corresponding to a model of the vehicle, wherein the plurality of model data points is representative of at least three degrees of freedom defining the pose of the model relative to the stereo camera, matching each of the plurality of model data points to a closest neighboring one of the plurality of scene data points according to a predetermined coarse-to-fine multi-resolution search approach, and, based on the results of the matching, determining at least three degrees of freedom defining the pose of the vehicle relative to the stereo camera. | 05-10-2012 |
Michael Borthwick, Brooklyn, NY US
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20100039783 | Apparatus For Adapting Mezzanine Cards - There is provided an apparatus for accommodating at least two different sized cards, the apparatus comprising a card housing comprising one or more card slots, each card slot being adaptable for inserting the at least two different sized cards; and a card guide system for adapting said one or more card slots for insertion of at least one of the at least two different sized cards. There is also provided a modified mezzanine card having at least one increased non-standard physical dimension relative to a standard mezzanine card suitable for insertion in the apparatus using the card guide system. | 02-18-2010 |
Michael M. Borthwick, Brooklyn, NY US
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20110228474 | ADVANCED MEZZANINE CARD FOR HOSTING A PMC OR XMC - A card assembly is disclosed comprising a carrier host card, an interposer printed wiring board (PWB) situated between the carrier host card and a hosted card, wherein the carrier host card and the interposer printed wiring board (PWB) are configured to have a space there-between. The card assembly further comprising a customized front panel including a first cutout for the carrier host card and a second cutout for said hosted card. | 09-22-2011 |
Sara Borthwick, San Francisco, CA US
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20110106584 | SYSTEM AND METHOD FOR MEASURING CUSTOMER INTEREST TO FORECAST ENTITY CONSUMPTION - A system and method comprises monitoring online user activity of one or more customers with regard to a first consumer entity. The user activity represents the one or more customer's interest in the first consumer entity categorized in a first product category. The method comprises monitoring the online user activity of the one more customers with regard to a second consumer entity categorized in a second product category different than the first category. The method comprises recording the monitored activity information to a data storage device and mapping it to a relational customer interest profile that represents a level of the one or more customer's interest at one or more corresponding phases of a consumption cycle with respect to the first and second consumer entities. The method comprises processing at least the mapped activity information to formulate a forecast of future consumption of at least the first consumer entity. | 05-05-2011 |
20120004983 | SYSTEMS AND METHODS FOR DETERMINING THE EFFICACY OF ADVERTISING - A computer-implemented method for determining effectiveness of content includes receiving, by a computing device, a plurality of attributes relating to rendered content, the plurality of attributes including at least one attribute that characterizes a consumer response to the rendered content and at least one attribute that characterizes a creative strength of the rendered content, generating, by a computing device, an index score indicative of an effectiveness of the content using a statistical analysis of the collected attributes, and storing the index score in memory. | 01-05-2012 |
Susan Elizabeth Borthwick, Tyne & Wear GB
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20100168277 | CURING AGENTS FOR EPOXY-FUNCTIONAL COMPOUNDS - The present invention relates to compounds suitable to use as curing agents for epoxy systems which can be obtained by reacting an amine-functional compound with an α-β unsaturated acid and/or ester and a mono-functional epoxy compound. The invention further relates to coating compositions comprising these curing agents. | 07-01-2010 |