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Boris R.
Boris R. Belitsky, Swampscott, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110104200 | Methods, compositions and kits for vegetative cell-based vaccines and spore-based vaccines - Methods for immunizing a subject to an antigen of an infectious agent, a tumor, or an allergen are provided, using vegetative cytoplasmic expression of the antigen or spore surface display of the antigen, and contacting the subject with a composition including a spore or a vegetative cell or both with or without an adjuvant. Also included are thermally-stable vaccine compositions using the method described above and kits including the compositions. | 05-05-2011 |
Boris R. Minev, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080206270 | Enhancing Class I Antigen Presentation With Synthetic Sequences - The invention relates generally to the treatment and prevention of human cancer and viral diseases. More specifically, this invention relates to development of a new generation of vaccines that rely on eliciting cellular immune responses, specifically induction of cytotoxic T lymphocytes (CTL), against cancer cells and virus-infected cells via administration of a vaccine comprising a fusion peptide or a modified peptide. Such a fusion peptide is composed of an insertion signal sequence and a peptide derived from a tumor antigen or a viral antigen, which improves antigen presentation and induces CTL with higher efficiency against cancer cells and virus-infected cells. An exemplary antigen utilized in the invention is HER2/neu. The peptides peptide vaccines of the invention are derived from the antigens PRAME, OFA/iLRP, STEAP and SURVIVIN. | 08-28-2008 |
Boris R. Teper, Farmington Hills, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110132153 | ADJUSTABLE COMBINATION TORQUE DRIVER - A torque driver includes a driver arm with a pivot mounting hole formed adjacent one end, a driver spindle mounting slot or sockets spaced from the pivot mounting hole providing multiple mounting positions for retaining the driver spindle, and a locking detent. A locking element engages the locking detent, a load applicator generates a selected load onto the locking element, and a handle is pivotally attached to the driver arm at the pivot mounting hole and has finger groove for applying a tightening force. The locking detent, the locking element and the load applicator cooperate to permit relative movement between the driver arm and the handle when the tightening force applied at the finger groove is at a pre-determined value. | 06-09-2011 |