Bordeleau
Francois Bordeleau, Brossard CA
Patent application number | Description | Published |
---|---|---|
20120046804 | METHOD AND SYSTEM FOR GENERATING A DATA SET - Systems, methods, and stored coded instruction sets for reducing the amount of data captured, i.e., retained, by a computerized system, such as an aircraft flight control or monitoring system. Such systems can, for example, be used in monitoring and/or controlling the operation of one or more aircraft engines, flight controls, or other aircraft systems, in order to optimize storage required for collected data, and/or to reduce or otherwise control the time required to off-load captured data to another computer system, such as a land-based analysis system. The amount of data collected, e.g., captured or retained in memory, may be reduced by discarding data points that are within a specified tolerance of, for example, a previously observed or expected value in a manner which assists with preserving the accuracy and precision of the original measured data. | 02-23-2012 |
Josée Bordeleau, Laval CA
Patent application number | Description | Published |
---|---|---|
20110294778 | HEPATITIS C INHIBITOR COMPOUNDS - Compounds of Formula (I) | 12-01-2011 |
20120077737 | HEPATITIS C INHIBITOR COMPOUNDS - Compounds of the invention, which are macrocyclic peptide analogs containing an acylsulfonamide moiety, maintain good activity against NS3 proteases containing clinically relevant resistance mutations for this class as represented by genotype 1a R155K, genotype 1b D168V and genotype 1a D168V resistance mutations. The compounds of the invention are useful as inhibitors of HCV NS3 protease for the treatment of hepatitis C viral infection. | 03-29-2012 |
Marc-Andre Bordeleau, Shawinigan CA
Patent application number | Description | Published |
---|---|---|
20130073725 | SYSTEM AND METHOD FOR AUTOMATED CONTENT DISTRIBUTION - A system and method for automated content distribution is disclosed. A content distribution system includes a detector module for intercepting a network communication and verifying whether content is available for a client, and a notification module coupled to the detector module for notifying the client that the content is available. A method for content distribution includes intercepting a network communication, analyzing the network communication for determining whether content is available for a client, and notifying the client that the content is available. | 03-21-2013 |
Marie-Eve Bordeleau, Montreal CA
Patent application number | Description | Published |
---|---|---|
20090118362 | CHEMOTHERAPEUTIC AGENTS FOR INHIBITION OF PROTEIN TRANSLATION - The present invention relates to a anti-proliferative target for designing chemotherapeutic agents, which comprises a EIF4A protein having an amino acid sequence, as defined in claim | 05-07-2009 |
20090186839 | Model for studying the role of genes in chemoresistance - The invention provides novel inhibitors of protein translation initiation and inhibitors of eIF4F activity that can increase chemosensitivity or diminish or reverse chemoresistance in growth transformed cells and thereby reduce hyperproliferative conditions, such as cancer progression, in select patient populations having particular tumor genotypes. The invention also provides methods which target translation initiation controls in growth-transformed cells, such as tumor subtypes with altered expression of a gene activity, including the human akt, bcl-2, eIF4E, eIF4A or PTEN activities, to restore drug sensitivity in vivo in a genotype selective manner. In one aspect, the inhibitors of translation initiation of the invention are rocaglates, i.e., cyclopenta[b]benzofurons, which increases chemosensitivity or diminishes or reverses chemoresistance either alone or in combination, additively or synergistically, with other agents that alter growth or death. Preferably, the rocaglate is silvestrol, which is used alone or in combination with doxorubicin to reverses chemoresistance in PTEN-deficient lymphomas or eIF4E-over-expressing lymphomas and to promote cancer remission. | 07-23-2009 |
Pierre Guy Bordeleau, Kapuskasing CA
Patent application number | Description | Published |
---|---|---|
20130233963 | Drop & roll dispenser - The portable Drop & Roll Dispenser or The General Dispensor, through its mobility and ease of use, is a tool to simplify convenience as to unroll a ball, a free spindle or any roll of material. Position the General Dispensor anywhere, drop your roll of material and use. | 09-12-2013 |