Boothman
David Boothman, Austin, TX US
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20130253046 | METHODS OF TREATING CANCER COMPRISING TARGETING NQO1 - Disclosed herein are methods for determining whether an individual with cancer is suitable for a treatment with an NQO1 bioactivatable drug, predicting responsiveness of an individual with cancer to a treatment with an NQO1 bioactivatable drug, and treating an individual with cancer with an NQO1 bioactivatable drug composition. | 09-26-2013 |
David Boothman, Dallas, TX US
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20130331426 | pH-SENSITIVE COMPOSITIONS FOR DELIVERY OF BETA LAPACHONE AND METHODS OF USE - Disclosed herein are compounds comprising a polymer conjugated with a pH-sensitive prodrug of beta-lapachone, wherein the compound is capable of forming a micelle, and wherein the pH-sensitive prodrug comprises a pH-sensitive linker selected from the group consisting of: an aryl imine and an aliphatic imine. Also provided are micelles comprised of such polymer-prodrug conjugates. Further provided are methods for treating cancer with the micelles. | 12-12-2013 |
20140023590 | NOVEL BLOCK COPOLYMER AND MICELLE COMPOSITIONS AND METHODS OF USE THEREOF - Provided herein are block copolymers comprising a hydrophilic polymer segment and a hydrophobic polymer segment, wherein the hydrophilic polymer segment comprises a polymer selected from the group consisting of: poly(ethylene oxide) (PEO), poly(methacrylate phosphatidyl choline) (MPC), and polyvinylpyrrolidone (PVP), wherein the hydrophobic polymer segment comprises wherein R′ is —H or —CH | 01-23-2014 |
David A. Boothman, Dallas, TX US
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20160030457 | TUMOR-SELECTIVE COMBINATION THERAPY - The therapies described herein can be selectively lethal toward a variety of different cancer cell types and cancer conditions in a subject. The combination therapies described herein can be useful for the management, treatment, control, or adjunct treatment of diseases, where the selective lethality is beneficial in chemotherapeutic therapy, particularly where the disease is accompanied by elevated levels of NQO1. | 02-04-2016 |
Jeff Boothman, Powell, OH US
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20130071605 | THIN-MEDIA PACKING MATERIAL - A packing chip formed from a flat intermediate sheet, and includes a central section and two outer sections located on opposite sides of the central section and a tab located on each of the two outer sections. Each section has a width and a depth. A securing element is on each tab for securing the tabs of the chip in an assembled shape. One or more apertures defined by at least one section are configured such that the packing chip forms interlocking engagement with portions of adjacent packing chips when employed as packaging. The sheet material has a thickness of less than about 0.014 inches. | 03-21-2013 |
20130071613 | SMALL DIMENSION PACKING MATERIAL - A packing chip is formed from a flat intermediate sheet and includes a central section and two outer sections located on opposite sides of the central section and a tab located on each of the two outer sections. Each section defines a width and a depth, which may each be between about 0.5 inches and about 0.75 inches. Securing elements for securing the tabs of the chips in an assembled shape are located on each tab. One or more apertures defined by at least one section are configured such that the packing chip forms interlocking engagement with portions of adjacent packing chips when employed as packaging. | 03-21-2013 |
Stuart Boothman, Keighley GB
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20130165881 | LEAKAGE-REDUCING DRESSING - An adhesive dressing that reduces the leakage of wound exudate from the dressing, comprising an adhesive-coated backing sheet; and an absorbent island adhered to said adhesive-coated backing sheet by said adhesive, having a first end and a second end, wherein the absorption capacity of the absorbent island is higher at the first end than at the second end. The adhesive dressing of the invention provides extended wear time for the dressing when it is applied to wounds. | 06-27-2013 |
William Terrence Boothman, Canandaigua, NY US
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20150058716 | SYSTEM AND METHOD FOR SUMMARIZING DOCUMENTS - A computer based system and method for exporting user-selected text by allowing a user to select a plurality of text segments, selecting from a block of text, flagging each of the text segments from a plurality of text segments such that each of text segments may be retrieved later, retrieving the plurality of text segments, and then exporting the plurality of text segments as data that may be read by a software application. The selected text segments may also be assigned one or more indicia for categorizing and sorting according to user-defined criteria. | 02-26-2015 |