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Bondarenko, US
Andrey Bondarenko, Bellevue, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20100106426 | REGIONS OF INTEREST PROCESSING - After prepared biological samples have been submitted to liquid-chromatography/mass spectrometry equipment, digital images are produced that show variations. Some of these variations may be of interest while others are not of interest. Variations in regions of interest can be correlated and correlation scores produced to classify biological features aid in scientific discovery. Shape properties of variations can also be calculated by geometric scores. A microalignment method aids the correlation calculation without resorting to macroalignment. | 04-29-2010 |
| 20100310138 | FINDING PAIRED ISOTOPE GROUPS - A technique for finding paired isotope groups of peptides, metabolic materials, or other materials is executed without having to identify features. Any suitable isotopic labeling methods, such as SILAC or ICAT, can be used. The technique can identify isotope pairs by pairing heavy and light labeled peptides based on mono-isotopes. The technique searches for isotope groups that have retention time and mass/charge within given tolerances, adjustable by users. Multiple label sites are supported as well as reverse-labeling to inhibit or reduce biases. Multiple replicates can be merged into a composite image. | 12-09-2010 |
| 20110110569 | DISCOVER BIOLOGICAL FEATURES USING COMPOSITE IMAGES - An image processing system extracts parts or characteristics of interest from prepared biological samples One suitable use of the image processing system is to find biomarkers. But many other suitable uses are possible. Some components of the system include image preprocessing (data interpolation, retention time alignment, image noise filtering, background estimation, and formation of a composite image); image feature extraction (peaks, isotope groups, and charge groups); and computation of feature characteristics and expression statistics, differential expression, and non-differential expression. Outputs of the system include a candidate list of parts or characteristic of interest for aiding further discovery. | 05-12-2011 |
Andrey Y. Bondarenko, Bellevue, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20120133532 | COMPRESSION AND DECOMPRESSION OF MASS SPECTROMETRY DATA - Functionality is described for compressing and decompressing mass spectrometry data, therefore making it easier to store, retrieve, transfer, and process the mass spectrometry data. The functionality operates by mapping data values (e.g., mass-to-charge data values or intensity data values) into index values, and then mapping the index values into delta values. The functionality then uses an encoding algorithm (such as a coding tree) to represent the delta values in compressed form. In a decoding stage, the functionality can interpret each encoded delta value with reference to a chain of preceding delta values, which ultimately link to an initial data value that is expressed in non-relative form. In one implementation, the functionality can define multiple such initial data values which correspond to multiple access points in a stream of compressed mass spectrometry data. | 05-31-2012 |
David J. Bondarenko, Topeka, KS US
| Patent application number | Description | Published |
|---|---|---|
| 20110007927 | BONE CONDUCTION COMMUNICATIONS HEADSET WITH HEARING PROTECTION - A communications headset includes bone vibrating transducers supported over the temporal bones of a wearer in front of each ear and an earpiece. The earpieces, when not in use, are selectively securable in a holster formed on each transducer housing. Radio signals received by a wearer or vehicular mounted radio are processed by and distributed through a communications interface to both the transducers and the earpiece speakers. Ambient or external noises picked up by one or more microphones on each earpiece are processed to reduce ambient noises above a certain level. | 01-13-2011 |
Oleg Bondarenko, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090077531 | Systems and Methods to Generate a Software Framework Based on Semantic Modeling and Business Rules - Systems and methods are provided to generate a software framework based on semantic modeling and business rules. In one embodiment, a method implemented in a data processing system, includes: receiving input from one or more first users to generate a first ontology describing a software requirement; receiving input from one or more second users to map the first ontology to a second ontology describing software tools; and generating a software framework in the data processing system based on the input received from the one or more second users to map the first ontology to the second ontology. | 03-19-2009 |
Paul J. Bondarenko, Gresham, OR US
| Patent application number | Description | Published |
|---|---|---|
| 20110067636 | INDEXED FEED DISPENSING MECHANISM - An improved livestock feeder provided with an adjustable feed dispensing mechanism including control levers which are operatively connected to the feed metering gates to control the flow of feed to livestock. The dispensing mechanism features a control lever which engage an array of indexing holes formed in the feeder to position the feed gate within the opening to adjust the amount of feed dispensed from the hopper. The dispensing mechanism includes a graduated scale corresponding to each of the index holes to provide a standard setting for the feeder which can be utilized by an animal producer to supply of feed flow at a given stage in the animal's life cycle to obtain a desired growth rate. | 03-24-2011 |
| 20110253052 | INDEXED FEED DISPENSING MECHANISM - An improved livestock feeder provided with an adjustable feed dispensing mechanism including control levers which are operatively connected to the feed metering gates to control the flow of feed to livestock. The dispensing mechanism features a control lever which engage an array of indexing holes formed in the feeder to position the feed gate within the opening to adjust the amount of feed dispensed from the hopper. The dispensing mechanism includes a graduated scale corresponding to each of the index holes to provide a standard setting for the feeder which can be utilized by an animal producer to supply of feed flow at a given stage in the animal's life cycle to obtain a desired growth rate. | 10-20-2011 |
Pavel Bondarenko, Thousand Oaks, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100158908 | Stable Polypeptide Formulations - The invention provides a formulation including a buffer having a pH less than 6.0, a divalent cation between about 5-200 mM, an excipient comprising a sugar or polyol and an effective amount of a therapeutic polypeptide. Also provided is a method of stabilizing a polypeptide. The method includes contacting a therapeutic polypeptide with a concentration of divalent cation between about 5-150 150 mM in a buffer having a pH less than 6.0 and an excipient comprising a sugar or polyol. | 06-24-2010 |
| 20100226925 | Homogeneous Antibody Populations - The present invention is generally directed to methods of producing an increase in the enrichment and/or recovery of preferred forms of monoclonal antibodies. More particularly, the invention relates to methods for eliminating disulfide heterogeneity in the hinge region of recombinant IgG2 antibody proteins. | 09-09-2010 |