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Bolt
George Bolt, Hampshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20080301075 | METHOD OF TRAINING A NEURAL NETWORK AND A NEURAL NETWORK TRAINED ACCORDING TO THE METHOD - A neural network comprises trained interconnected neurons. The neural network is configured to constrain the relationship between one or more inputs and one or more outputs of the neural network so the relationships between them are consistent with expectations of the relationships; and/or the neural network is trained by creating a set of data comprising input data and associated outputs that represent archetypal results and providing real exemplary input data and associated output data and the created data to neural network. The real exemplary output data and the created associated output data is compared to the actual output of the neural network, which is adjusted to create a best fit to the real exemplary data and the created data. | 12-04-2008 |
George Bolt, Midhurst GB
| Patent application number | Description | Published |
|---|---|---|
| 20090164761 | HIERARCHICAL SYSTEM AND METHOD FOR ANALYZING DATA STREAMS - A method for analyzing data streams comprises receiving a data stream, conducting a first analysis of the data stream for a possible target activity, and if a possible target activity is indicated generating a first alert. If the first alert is generated, a second analysis for the possible target activity is conducted to determine whether the target activity is indicated in the data stream with a high degree of certainty. If a possible target activity is indicated by the second analysis, a second alert is generated and provided to an external system for action. | 06-25-2009 |
Gert Bolt, Vaerlose DK
| Patent application number | Description | Published |
|---|---|---|
| 20080227691 | Blood Coagulation FVIII Analogues - The invention is related to a FVIII analogue which has a circulation time in the blood stream before activation of at least about two times of that of native FVIII and a week after injection to a patient retains at least about 5% of the FVIII activity compared to the initial activity peak value reached after injection. The claimed FVIII analogues comprise a targeted disruption of one or more of the clearance sites in the FVIII molecule by introduction of at least one N-glycosylation site or by introduction of at least one Cys residue within or spatially close to the clearance site in the A2 domain or a combination thereof. The inserted cysteine residues may be further modified by conjugation with a chemical group increasing the molecular weight of the FVIII analogue. | 09-18-2008 |
| 20100120094 | FACTOR VIII POLYPEPTIDE TITERS IN CELL CULTURES - The invention relates to a method for the production of a Factor VIII polypeptide, the method comprising the steps of a) culturing a mammalian cell expressing a Factor VIII polypeptide under conditions for expression of said Factor VIII polypeptide, said culturing conditions involving a cell culture medium comprising a C2-domain ligand, and b) isolating the expressed Factor VIII polypeptide from the mammalian cell by suitable means. | 05-13-2010 |
| 20110118183 | N-GLYCOSYLATED HUMAN GROWTH HORMONE WITH PROLONGED CIRCULATORY HALF-LIFE - The present invention relates to novel human growth hormone (hGH) variant(s) with one or more N-glycans. The hGH variants of the invention comprises an amino acid sequence which includes at least one N-glycosylation motif (N-X-S/T) arising from one or more mutations not present in the wild type hGH. The hGH variants of the invention have a prolonged circulatory half-life and thus can be effectively used as a protein therapeutic for disease states that will benefit from increased levels of hGH. The process of obtaining the hGH variants is also encompassed by the invention. | 05-19-2011 |
| 20110137011 | HYPERGLYCOSYLATED HUMAN COAGULATION FACTOR IX - The invention relates to hyperglycosylated human coagulation factor IX polypeptides, to processes for preparing said polypeptides, to pharmaceutical compositions comprising said polypeptides and to the use of the compounds for the treatment of diseases alleviated by human coagulation factor IX, in particular, but not exclusively hemophilia. | 06-09-2011 |
Randy Bolt, Newmarket CA
| Patent application number | Description | Published |
|---|---|---|
| 20090008894 | STEP ASSIST BOX-SIDE - A step assembly is provided for a bumper of a motor vehicle. The step assembly includes a mounting bracket fixedly secured to the bumper. A step is operatively coupled to the mounting bracket and is movable between a retracted position disposed adjacent the bumper and a deployed position extending away from the bumper. A pivot arm is pivotally interconnected between the mounting bracket and the step. A spring is secured between the mounting bracket and the pivot arm for biasing the pivot arm. The spring creates a tensile force. A lock arm is pivotally interconnected between the mounting bracket and the step. The lock arm defines a lock surface engaging the pivot arm while the tensile force of the spring locks the step in order to retain the step in one of the retracted and deployed positions. | 01-08-2009 |
Roderick Mark Bolt, Kensington Park AU
| Patent application number | Description | Published |
|---|---|---|
| 20100162595 | MOUNTING OF WEAR MEMBERS - A retaining pin assembly for an excavator tooth assembly. The retaining pin assembly has opposable locating members each having a shank portion able to be slidably insertable via a respective retaining pin aperture on opposite sides of a wear member into a transversely extending mounting aperture of a mounting nose of an excavator. Each locating member also has an enlarged inwardly convergent tapered wedge portion adjacent a normally outer end. The retaining pin assembly also has a tensionable retaining member extending between the locating members from one side of the retaining pin assembly. When tension is applied to the retaining member relative contraction of the locating members occurs to urge the wear member into engagement with the mounting nose by wedging engagement between each of the wedge portions and a rear wall of respective retaining pin apertures. | 07-01-2010 |
Stephen Bolt, Kanata CA
| Patent application number | Description | Published |
|---|---|---|
| 20080303794 | SYSTEM AND METHOD FOR MANAGING MEDIA DATA IN A PRESENTATION SYSTEM - A media integration device associated with a touch system including a touch screen, comprises a media control module operative to receive media information from a plurality of devices and generate media data associated with each of the plurality of devices. The media control module selects one device from the plurality of devices for displaying media data associated with the one device on the touch screen. A program module is operatively coupled to the media control device and adapted to generate a graphical user interface including a first display on the touch screen for operationally controlling the selected one device from the touch screen. | 12-11-2008 |
Stephen Bolt, Stittsville CA
| Patent application number | Description | Published |
|---|---|---|
| 20090277697 | Interactive Input System And Pen Tool Therefor - A pen tool for use with an interactive input system comprises an elongate body, at least one switch assembly accommodated by the body and a controller accommodated by the body and communicating with the at least one switch assembly. The at least one switch assembly is actualable when the pen tool is brought into contact with an input surface of the interactive input system. The controller is responsive to actuation of the at least one switch assembly. The at least one switch assembly comprises a contact circuit and a plunger assembly having a conductive element thereon that is generally aligned with the contact circuit. The plunger assembly is moveable into the body to bring the conductive element into contact with the contact circuit thereby actuate the at least one switch assembly. | 11-12-2009 |
Stephen Patrick Bolt, Stittsville CA
| Patent application number | Description | Published |
|---|---|---|
| 20110169736 | INTERACTIVE INPUT SYSTEM AND TOOL TRAY THEREFOR - An interactive input system comprises an interactive surface and a tool tray supporting at least one tool to be used to interact with the interactive surface. The tool tray comprises processing structure for communicating with at least one imaging device and processing data received from the at least one imaging device for locating a pointer positioned in proximity with the interactive surface. | 07-14-2011 |