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Boger, US
Dale Boger, Lajolla, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110112163 | CBI DERIVATIVES SUBJECT TO REDUCTIVE ACTIVATION - A unique class of N-acyl O-amino phenol prodrugs of CBI-TMI and CBI-indole | 05-12-2011 |
Dale L. Boger, La Jolla, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080267981 | Compositions and Methods for Delivery of Antitumor Agents - Methods for treating a neoplastic disease with an antibody-cytotoxin conjugate molecule, methods of synthesizing an antibody-cytotoxin conjugate molecule are provided. Compounds that are useful as antibody-cytotoxin conjugate molecule or useful in the synthesis of these molecules are also provided. | 10-30-2008 |
| 20090270421 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE - Potent inhibitors of fatty acid amide hydrolase (FAAH) are constructed having K | 10-29-2009 |
| 20100075931 | Substituted oxazole ketone modulators of fatty acid amide hydrolase - Certain oxazole ketone compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis). | 03-25-2010 |
| 20100216750 | TRICYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE - A series of substituted oxazole compounds having an alpha keto side chain at the 2 position and an aromatic, heteroaromatic or heterocycle substituent at the 5 position are disclosed. These compounds exhibit inhibition of fatty acid amid hydrolase and arc useful for treatment of malconditions involving that enzyme. | 08-26-2010 |
| 20100249078 | TETRACYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE - Certain tetracyclic compounds are described, which may be used in pharmaceutical compositions and methods for treating disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis). | 09-30-2010 |
| 20110183947 | ALPHA-KETO HETEROCYCLES AS FAAH INHIBITORS - The invention provides a series of -αketoheterocyclic compounds, for example, compounds of formula (I). The compounds can inhibit fatty acid amide hydrolase and can be useful for treatment of malconditions modulated by fatty acid amide hydrolase. The invention further provides methods of making compounds of formula (I), useful intermediates for the preparation of compounds of formula (I), and methods of using compounds of formula (I) and compositions thereof. | 07-28-2011 |
| 20110184026 | C4-SUBSTITUTED ALPHA-KETO OXAZOLES - The invention provides a series of C4-substituted oxazole compounds having an alpha keto side chain at the 2 position, for example, compounds of formula I. The compounds can inhibit fatty acid amide hydrolase and can be useful for treatment of malconditions modulated by fatty acid amide hydrolase. The invention further provides methods of making compounds of formula I, useful intermediates in the preparation of compounds of formula I, and methods of using compounds of formula I and compositions thereof. | 07-28-2011 |
David A. Boger, Glenside, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090060743 | Expandable impeller pump - An impeller includes a hub, and a plurality of blades supported by the hub, the blades being arranged in at least two blade rows. The impeller has a deployed configuration in which the blades extend away from the hub, and a stored configuration in which at least one of the blades is radially compressed, for example by folding the blade towards the hub. The impeller may also have an operational configuration in which at least some of the blades are deformed from the deployed configuration upon rotation of the impeller when in the deployed configuration. The outer edge of one or more blades may have a winglet, and the base of the blades may have an associated indentation to facilitate folding of the blades. | 03-05-2009 |
| 20110236210 | EXPANDABLE IMPELLER PUMP - An impeller includes a hub, and a plurality of blades supported by the hub, the blades being arranged in at least two blade rows. The impeller has a deployed configuration in which the blades extend away from the hub, and a stored configuration in which at least one of the blades is radially compressed, for example by folding the blade towards the hub. The impeller may also have an operational configuration in which at least some of the blades are deformed from the deployed configuration upon rotation of the impeller when in the deployed configuration. The outer edge of one or more blades may have a winglet, and the base of the blades may have an associated indentation to facilitate folding of the blades. | 09-29-2011 |
David A. Boger, Jenkintown, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110071338 | HEART ASSIST DEVICE WITH EXPANDABLE IMPELLER PUMP - An impeller includes a hub and at least one blade supported by the hub. The impeller has a stored configuration in which the blade is compressed so that its distal end moves towards the hub, and a deployed configuration in which the blade extends away from the hub. The impeller may be part of a pump for pumping fluids, such as pumping blood within a patient. A blood pump may include a cannula having a proximal portion with a fixed diameter, and a distal portion with an expandable diameter. The impeller may reside in the expandable portion of the cannula. The cannula may have a compressed diameter which allows it to be inserted percutaneously into a patient. Once at a desired location, the expandable portion of the cannula may be expanded and the impeller expanded to the deployed configuration. A flexible drive shaft may extend through the cannula for rotationally driving the impeller within the patient's body. | 03-24-2011 |
David K. Boger, Vestavia Hills, AL US
| Patent application number | Description | Published |
|---|---|---|
| 20090069844 | Closure Device, Deployment Apparatus, and Method of Deploying a Closure Device - The present invention relates generally to medical devices and methods for sealing and closing passages formed through tissue. More specifically, the present invention relates to devices for sealing or closing an opening formed through biological tissue comprising a distal or outside margin or surface, and a proximal or inside margin or surface (i.e., a wall thickness), and to apparatuses and methods for delivering such devices, to control (or prevent or stop) bleeding (or the flow of other biological fluid or tissue). The openings comprise percutaneously formed punctures, incisions, or other openings formed through biological tissue, such as in blood vessels, organs, and the like. | 03-12-2009 |
| 20110046665 | Closure Device, Deployment Apparatus, and Method of Deploying a Closure Device - The present invention relates a closure device implant for sealing an opening formed through biological tissue including a plug, a rigid wire including a plastically deformable portion configurable between an unrestrained position and a restrained position relative to the plug, wherein a distal end of the wire is substantially spherically shaped, and a footplate attached to the wire, wherein the footplate comprises an elongated plate portion including a wire channel. The present invention also relates to a closure device deployment device including an elongated housing, a sheath assembly connected to the housing, and at least two sliding members slidably connected to the housing. | 02-24-2011 |
Henry W. Boger, Foxboro, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080269951 | Controlling Fluid Regulation - Fluid regulation control may be accomplished by a variety of systems, devices, and techniques. In one application, a fluid regulation control device may include a processor, a fluid control assembly, and a power source. The processor may be adapted to generate a command for controlling a fluid regulator and to adjust a power condition of the device, which may include a low power mode and a high power mode. The device may consume substantially less power in the low power mode than in the high power mode. The fluid control assembly may include a transducer, which may receive a control fluid and adjust it in response to the command during the high power mode. The fluid control assembly may also maintain the adjusted control fluid at a substantially constant value during the low power mode. | 10-30-2008 |
| 20090216350 | CONTROL VALVE AND POSITIONER DIAGNOSTICS - Valve positioning systems may include one or more components and a controller. Components may include one or more electric-to-pressure output converters, relays, gas supplies, and/or actuators. A controller may adjust a position of a valve by sending a signal. The valve positioning system may individually monitor components and determine the condition of each component being individually monitored. The valve positioning system may determine if a component will fail prior to failure and/or determine if a problem will occur in a component prior to the problem occurring. | 08-27-2009 |
| 20100057262 | FLUID PROCESS CONTROL - A fluid regulator characterization system can characterize the flow of a fluid regulator that results in response to a received control signal. The fluid regulator characterization system can use the characterization to achieve a linear fluid regulator flow gain over a full operating range (e.g., zero percent travel to one hundred percent travel) for the fluid regulator relative to the received control signal. A linear fluid regulator flow gain can improve process control and reduce process variability. | 03-04-2010 |
Joshua Boger, Concord, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100249100 | QUINAZOLINES USEFUL AS MODULATORS OF ION CHANNELS - The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels and calcium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. | 09-30-2010 |
Robert A. Boger, Sioux City, IA US
| Patent application number | Description | Published |
|---|---|---|
| 20090086095 | Method and apparatus for overlaying encoded streams - A display device for overlaying encoded steams includes a decoder within the display device for decoding a primary encoded stream and a secondary encoded stream to produce a primary unencoded stream and a secondary unencoded stream including secondary information and overlay information. The display device includes an overlay controller for combining the primary unencoded stream and the secondary unencoded stream to produce a composite stream. The display device includes a display adapted to display images corresponding to the composite stream, the images including a primary image corresponding to the primary unencoded stream and a secondary image corresponding to the secondary information overlaid on the primary image corresponding to the overlay information. | 04-02-2009 |
| 20090094661 | Networked personal video recorder backup system - Methods, systems and computer software products are provided for backing up the recording of television events by a primary recording device when the primary recording device fails or is unavailable. One or more backup video recording devices is specified in a networked household entertainment system for backing up the primary recording device. If the primary recording device is powered down, fails, or is otherwise unavailable at the time the television event is aired, the controller of the networked household entertainment system instructs one of the backup recording devices to record the event. | 04-09-2009 |
Thorsten Rolf Boger, Painted Post, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20120134891 | Porous Ceramic Honeycomb Articles and Methods for Making The Same - A porous ceramic honeycomb article comprising a honeycomb body formed from cordierite ceramic, wherein the honeycomb body has a porosity P %≧55% and a cell channel density CD ≧150 cpsi. The porous channel walls have a wall thickness T, wherein (11+(300−CD)*0.03)≧T≧(8+(300−CD)*0.02), a median pore size ≦20 microns, and a pore size distribution with a d-factor of ≦0.35. The honeycomb body has a specific pore volume of VP≦0.22. The porous ceramic honeycomb article exhibits a coated pressure drop increase of ≦8 kPa at a flow rate of 26.5 cubic feet per minute when coated with 100 g/L of a washcoat catalyst and loaded with 5 g/L of soot. | 05-31-2012 |
| 20120230881 | HONEYCOMB FILTERS FOR REDUCING NOx AND PARTICULATE MATTER IN DIESEL ENGINE EXHAUST - Particulate filters for reducing NO | 09-13-2012 |
Tyler K. Boger, Novi, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20090020929 | Strut Top Mount With Axial Hydraulic Element - A hydraulic element for use in vehicle mount applications includes a housing, a spring assembly disposed within the housing, and an external component outside of the housing. A first chamber is defined between the spring assembly and the housing. Furthermore, a second chamber is defined within the external component and is in fluid communication with the first chamber. With the external component providing the second chamber outside of the housing, the hydraulic element can be formed with a relatively compact configuration. | 01-22-2009 |
| 20090102218 | Body Mount Assembly With Hydraulic Damping Capability - A body mount assembly for reducing vibration between a vehicle body and a frame. The body mount includes a hydraulic radial bushing including an inner sleeve and an outer sleeve coaxial with the inner sleeve and having a hydraulic damping system disposed between the inner sleeve and the outer sleeve. A bottom retainer is positioned below a first end of the hydraulic radial bushing. An upper retainer is positioned above a second end of the hydraulic radial bushing. A flange bracket includes an axial sleeve portion coaxially surrounding the radial bushing and a plate portion extending from an end of the axial sleeve portion and including mounting apertures adapted for mounting the flange bracket to the vehicle frame. A vertical isolator is disposed between the upper retainer and the flange bracket. | 04-23-2009 |
Yuval Boger, Pikesville, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20120262558 | APPARATUS, SYSTEMS AND METHODS FOR PROVIDING MOTION TRACKING USING A PERSONAL VIEWING DEVICE - An apparatus, methods and systems to provide a personal viewing device configured to display an image. The personal viewing device configured to be worn by a user. At least one sensor coupled to the personal viewing device. At least one camera coupled to the personal viewing device and facing outwardly with respect to the personal viewing device. A processor configured for interaction analysis. The processor in communication with the personal viewing device, the at least one sensor and the at least one camera. | 10-18-2012 |
Yuval S. Boger, Baltimore, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090059364 | SYSTEMS AND METHODS FOR ELECTRONIC AND VIRTUAL OCULAR DEVICES - An ocular device is be used to magnify virtual and real scenes in a binocular or monocular configuration. A plurality of lenses is positioned as though each of the lenses is tangent to a surface of a first sphere having a center that is located substantially at a center of rotation of an eye of a user. A plurality of displays is positioned as though each of the displays is tangent to a surface of a second sphere having a radius larger than the first sphere's radius and having a center that is located at a center of rotation of the eye. Each of the displays corresponds to at least one of the lenses, and is imaged by the corresponding lens. A processor displays an image to the user using the plurality of displays. An input device allows the user to adjust a magnification of the image. | 03-05-2009 |
| 20110241976 | SYSTEMS AND METHODS FOR PERSONAL VIEWING DEVICES - Images are overlaid using a personal viewing device, such as a head mounted display. The personal viewing device includes a mount, an electronic display, a lens, and an electronic circuit. The electronic display, lens, and electronic circuit are physically attached to the mount. The electronic display and lens are positioned by the mount so that an eye views the electronic display through the lens. The electronic circuit overlays a first image with a second image to produce an overlaid image. The electronic circuit then displays the overlaid image on the electronic display. The electronic circuit can include an image generating device. The image generating device can generate the first image and/or the second image. The image generating device can be a video player or a processor. The personal viewing device can further include a wireless transceiver attached to the mount. | 10-06-2011 |