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Bo Rud
Bo Rud Nielsen, Alleroed DK
| Patent application number | Description | Published |
|---|---|---|
| 20100100009 | Device Having a Hydrophilic Coating Comprising P-Toluene-Sulfonamide and a Method for the Preparation Thereof - The present invention provides a medical device having a substrate polymer surface carrying thereon a hydrophilic coating comprising a cross-linked hydrophilic polymer and p-toluenesulfonamide, and a method for the preparation thereof. | 04-22-2010 |
| 20100247925 | Preparation of hydrophilic coatings utilizing a 1,3-dioxolane compound - A method for the preparation of a package comprising a packing means holding a medical device element of a substrate polymer, said substrate polymer having on at least a part of the surface thereof a hydrophilic coating, wherein the hydrophilic coating has been applied to the surface of said substrate polymer in the form of a solution of a hydrophilic polymer selected from the groups consisting of polyvinylpyrrolidone and polyethylene oxide in a vehicle comprising an optionally substituted 1,3-dioxolane compound, followed by evaporation of at least part of the vehicle and arranging said medical device element having the coating of the non-cross-linked hydrophilic polymer within a packing means, and sealing said packing means. | 09-30-2010 |
| 20110106061 | BUFFERED SWELLING MEDIA FOR RADIATION STERILIZED HYDROPHILIC COATINGS - To identify an alternative swelling medium with a hydrophilic polymer, we have observed that a swelling medium containing only 6% PEG 2000 and 0.9% NaCl failed to protect a hydrophilic coating during electron beam sterilization and subsequent storage at ambient and higher temperatures in an accelerated storage stability test. An unacceptably low dry-out time, below the specified 5 minutes, was obtained. However, when the biological buffer sodium citrate was added to a swelling medium containing PEG 2000, the performance of the stored catheters was as good as or better than the performance of catheters stored with the conventional swelling medium. | 05-05-2011 |
Bo Rud Nielsen, Allerod DK
| Patent application number | Description | Published |
|---|---|---|
| 20100119833 | PHOTO-CURING OF THERMOPLASTIC COATINGS - The present invention relates to a method for the preparation of a medical device element by means of extrusion or injection moulding and to medical devices comprising such extruded or injection moulded medical device elements. The medical device elements (e.g. tubes, wires, lines, stents, catheters, guides, endodontic instruments, needles, trocars for e.g. laparoscopic surgery, laparoscopic accessories, surgical instruments, guide wires) are characterized by a prefabricated shaped article or a thermoplastic substrate polymer having thereon a layer of a covalently cross-linked coating composition of a thermoplastic matrix polymer and a hydrophilic polymer. The method involves a coating composition comprising a thermoplastic matrix polymer, a hydrophilic polymer, and one or more photo-initiator(s), e.g. covalently linked to molecules of the thermoplastic matrix polymer and/or to molecules of the hydrophilic polymer. The coating composition is irradiated with UV or visible light so as to covalently cross-link said coating composition. | 05-13-2010 |
Bo Rud Nielsen, Humlebaek DK
| Patent application number | Description | Published |
|---|---|---|
| 20100049146 | COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS - The application discloses a method for the preparation (by extruding, injection moulding or powder coating and subsequent cross-linking by irradiation with UV or visible light) of a medical device element involving a coating composition comprising: a) as the only polymer constituent(s), at least 50% by weight of poly(ethylene oxide)(s) optionally in combination with non-thermoplastic hydrophilic polymer(s), and b) low molecular weight scaffold(s) having a plurality of photo-initiator moieties covalently linked thereto and/or covalently incorporated therein, wherein the photo-initiator moieties constitute 0.01-20% by weight of the combined amount of the poly(ethylene oxide)(s), any non-thermoplastic hydrophilic polymers and the low molecular weight scaffolds. The application further discloses such extruded, injection moulded or powder coated medical devices having thereon a layer of a covalently cross-linked coating composition of a poly(ethylene oxide) (PEO), optionally a non-thermoplastic hydrophilic polymer and a low molecular weight scaffold having a plurality of residues of photo-initiator moieties. | 02-25-2010 |