| Patent application number | Description | Published |
|---|
| 20090306430 | Use of Guanabenz and Its Derivatives for Making Drugs for Treating Cystic Fibrosis and Diseases Related to a Protein Addressing Deficiency in the Cells - The invention concerns the use of guanabenz and its derivatives for making drugs for treating cystic fibrosis and diseases related to a protein addressing deficiency in the cells, said derivatives corresponding to formula (I), wherein: R═H or C1 and the phenyl group comprises two substituents, or a pharmaceutically acceptable salt of said derivatives. | 12-10-2009 |
| 20100036166 | Use of chlorine guanabenz derivatives for treating polyglutamine expansion associated diseases - The invention relates to chlorine Guanabenz derivatives for treating Huntington's disease and other polyglutamine expansion associated diseases. More specifically, it relates to the use of the molecule of formula (I) wherein R═H or Cl and the phenyl group is at least substituted twice, or a pharmaceutically acceptable salt thereof, for the manufacture of a medicament for treating polyglutamine expansion associated diseases. | 02-11-2010 |
| 20110092483 | SCREENING MOLECULES WITH ANTI-PRION ACTIVITY: KITS, METHODS AND SCREENED MOLECULES - A kit and a method for identifying compounds having anti-prion activity are provided. The kit comprises a yeast of phenotype [PSI+]; an antibiogram; and a prion curing agent in a sub-effective dose, wherein the yeast has the adel-14 allele of the ADE1 gene and an inactivated ERG6 gene. Compounds and pharmaceutical compositions having anti-prion activity are also provided, which are useful for treating various neurodegenerative diseases, including polyglutamines expansion associated diseases; Huntington's disease; Kennedy disease; amyotrophic lateral sclerosis; cerebellous autosomic ataxies; dentalorubral-pallidoluysian atrophy; and spino-bulbar amyotrophy. | 04-21-2011 |
| Patent application number | Description | Published |
|---|
| 20080249238 | FLEXIBLE SEMIAROMATIC POLYAMIDES WITH A LOW MOISTURE UPTAKE - The present invention relates to a flexible semiaromatic polyamide composition with a low moisture uptake, made up by weight, the total being 100:
| 10-09-2008 |
| 20090253836 | FLEXIBLE HIGH THERMOMECHANICAL STRESS-RESISTANT AND FIREPROOF HALOGEN-FREE THERMOPLASTIC COMPOSITIONS - The present invention relates to flame-retarded flexible thermoplastic compositions of high thermomechanical strength, containing no halogen compound, comprising a graft copolymer containing polyamide blocks and composed of a polyolefin backbone and on average at least one polyamide graft, in which the grafts are attached to the backbone by the radicals of an unsaturated monomer (X) having a function capable of reacting with an amine-terminal polyamide, the radicals of the unsaturated monomer (X) being fixed to the backbone by grafting or copolymerization from its double bond, wherein said composition comprises, in a mixture:
| 10-08-2009 |
| 20090264601 | COPOLYMERS HAVING AMIDE UNITS AND ETHER UNITS WITH IMPROVED OPTICAL PROPERTIES - A subject-matter of the present invention is a copolymer based on amide units and based on ether units, the amide units being composed predominantly of an equimolar combination of at least one diamine and of at least one dicarboxylic acid, the diamine or diamines being predominantly cycloaliphatic and the dicarboxylic acid or acids being predominantly linear aliphatic, it being possible for the amide units optionally to comprise, but to a minor extent, at least one other polyamide comonomer, the respective proportions of monomers of the ether and amide units being chosen so that:
| 10-22-2009 |
| 20090306308 | AMORPHOUS COPOLYAMIDES COMPRISING P-BIS (AMINOCYCLOHEXYL) METHANE AND TEREPHTALIC ACID - The present invention relates to amorphous transparent copolyamides of formula: PACM.T/D.X/X1.Y1 resulting from the condensation of PACM, terephtalic acid, a diamine D, a diacid X, a diamine X1 and a diacid Y1 in which: PACM denotes the p-bis(aminocyclohexyl)methane, T denotes terephtalic acid, D denotes a diamine chosen from aromatic, arylaliphatic and cycloaliphatic diamines, X denotes a diacid HOOC—(CH | 12-10-2009 |
| 20090318630 | BLENDS AND ALLOYS BASED ON AN AMORPHOUS TO SEMICRYSTALLINE COPOLYMER, COMPRISING AMIDE UNITS AND COMPRISING ETHER UNITS, WHEREIN THESE MATERIALS HAVE IMPROVED OPTICAL PROPERTIES - Transparent blend or alloy comprising, by weight, the total being 100%: (A) 1 to 99% of at least one copolymer constituent: which is amorphous or has a crystallinity ranging up to semicrystallinity; and which comprises: (A1) amide units, among which is at least one cycloaliphatic unit; (A2) flexible ether units; (B) 99 to 1% of at least one polymer constituent selected from: (Ba) semicrystalline copolyamides comprising amide units (Ba1) and comprising ether units (Ba2), (Bb) semicrystalline polyamides or copolyamides without ether units, (Bc) transparent polyamides or copolyamides without ether units, which are amorphous or weakly crystalline, and alloys based on such polyamides or copolyamides; and (C) 0 to 50% by weight of at least one polyamide, copolyamide, copolyamide comprising ether units or alloy based on such polyamides or copolyamides other than those used in (A) and (B) above. The resulting blend or alloy has a high transparency such that the transmission at 560 nm on a plate 2 mm thick is greater than 50%. | 12-24-2009 |
| 20100140846 | COMPOSITION BASED UPON A POLYAMIDE THAT IS AMORPHOUS AND TRANSPARENT OR HAS VERY LOW CRYSTALLINITY, AND UPON A COPOLYAMIDE WITH ETHER AND AMIDE UNITS - “Composition composed of a mixture of: 60 to 99% by weight of a polymer component (A) formed from at least one of the homopolyamides and copolyamides: a) that are transparent and amorphous or present crystallinity such that the enthalpy of fusion during the second heating of an DSC ISO (delta Hm(2) is at most 30 J/g, the mass being related to the number of amide units contained or polyamide contained, this melting corresponding to that of the amide units; b) presenting a glass transition temperature (Tg) of greater than 90° C.; and c) composed at least in part of cycloaliphatic and/or aromatic units, and/or alloys based on at least one previously cited homopolyamide or copolyamide, said alloys being amorphous or presenting crystallinity meeting the same definition as hereinabove; 40 to 1% by weight of a polymer component (B) formed by at least one copolyamide based on ether units and amide units; the polymer components (A)+(B) representing 100% by weight; where at least one among (A) and (B) may additionally contain at least one additive usual for thermoplastic polymers and copolymers, without the content of said additive or additive(s) in each of the polymer components (A) and (B) representing more than 30% by weight of the said polymer component.” | 06-10-2010 |
| 20110031155 | FLEXIBLE SEMICRYSTALLINE POLYAMIDES - The invention relates to a multilayer structure in which the inner layer is in contact with petrol or diesel fuel and comprising, in succession from the outside inwards:
| 02-10-2011 |
| 20110135860 | BLENDS OF TRANSPARENT AMORPHOUS POLYAMIDES BASED ON DIAMINES AND ON TETRADECANEDIOIC ACID AND SEMICRYSTALLINE POLYAMIDES - The present invention relates to a transparent amorphous polyamide which results from the condensation of at least one diamine chosen from aromatic, arylaliphatic and cycloaliphatic diamines, of tetradecanedioic acid or of a mixture comprising at least 50 mol % of tetradecanedioic acid and at least one diacid chosen from aliphatic, aromatic and cycloaliphatic dicarboxylic acids. The invention also relates to a composition comprising, by weight, 1 to 100% of the preceding polyamide and 99 to 0% of a semicrystalline polyamide. The invention also relates to the objects composed of the composition of the invention, such as panels, films, sheets, pipes, profiles or objects obtained by injection moulding. The invention also relates to objects covered with a transparent protective layer composed of the composition of the invention. | 06-09-2011 |
| 20110171408 | Copolyamide, composition comprising such a copolyamide and their uses - The present invention relates to a copolyamide comprising at least two units and corresponding to the following general formula: | 07-14-2011 |
| 20110195215 | SEMI-AROMATIC COPOLYAMIDE AND PROCESS FOR PREPARING SAME - The invention relates to a copolyamide comprising at least two units corresponding to the following general formula: | 08-11-2011 |
| 20110206881 | SEMIAROMATIC POLYAMIDE COMPRISING A CHAIN ENDING - The invention relates to a copolyamide comprising at least two different units corresponding to the following general formulation: | 08-25-2011 |
