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Block, DE

Andreas Block, Lubeck DE

Patent application numberDescriptionPublished
20100004725HELICAL IMPLANT HAVING DIFFERENT ENDS - Preferred embodiments of an implantable medical device with a high degree of flexibility is shown and described. One aspect includes an implantable stent having an intermediate portion with a helical winding and first and second end portions. The implantable stent further includes a coupling portion with a helical winding, and bridges joining struts of defining the helical windings. The stent also includes a paddle providing a bridge joining the ends or the helical windings. Another aspect relates to a radially self-expansible stent with a plurality of radiopaque markers attached to it. The markers are shaped and located at the stent end such that the compressive stress exerted on the end annulus of the stent during release of the stent is shared between the markers and the inflection zones that do not carry a marker.01-07-2010

Andreas Block, Rietheim DE

Patent application numberDescriptionPublished
20100298921BEND-CAPABLE TUBULAR PROSTHESIS - Stent exhibiting a succession of turns around the axis, adjacent turns being connected by connector portions distributed around the circumference of the prosthesis, each of the turns being made up of struts that extend the length of the turn and are interspersed by inflection zones located at the axial ends of each of the turns. When the prosthesis expands radially, gaps open up between adjacent struts of each of the turns, the inflection zones being distributed regularly around the circumference so that the gaps are substantially the same size as each other around the circumference of the turn, characterised in that at least every second turn exhibits a stagger zone within which the said gap between adjacent said struts is of an individual size different from that common to the other gaps of that second turn.11-25-2010

Bernd Block, Rostock DE

Patent application numberDescriptionPublished
20090107516STENT MADE OF NITINOL HAVING IMPROVED AXIAL BENDING STIFFNESS AND ASSOCIATED PRODUCTION METHOD - A stent made of nitinol having improved axial or radial stiffness, the stent having a support structure which comprises peripheral struts around the circumference, wherein the peripheral struts are linked to one another in the axial direction via connection struts. The support structure may assume a first compressed state and a second expanded state. The nitinol is in the support structure in a martensitic microstructure in the compressed state and largely in an austenitic microstructure in the second expanded state. One or more support structure sections, however, are entirely or partially in a martensitic microstructure in the second expanded state.04-30-2009
20100087915Implant and Method for Manufacturing Same - The present invention relates to a method for manufacturing an implant, in particular an intraluminal endoprosthesis, with a body containing metallic material, preferably iron. To control the degradation of the implant, the method comprises the following steps: a) preparing the body of the implant, and b) incorporating hydrogen into at least a portion of the structure of the implant body near the surface. Furthermore, such an implant is described.04-08-2010
20100087916Implant and Method for Producing a Degradation-Inhibiting Layer on the Surface of an Implant Body - A method for manufacturing a degradation-inhibiting first layer on the surface of an implant body, in particular an intraluminal endoprosthesis, whereby the body has at least one metallic material, which is at least largely biodegradable, comprising the following steps: preparing the body of the implant, and applying the first layer to at least a portion of the body surface, whereby the first layer contains magnesium stearate. An implant obtainable by such a method.04-08-2010
20100137971Stent with a Structure of a Biocorrodible Material and a Controlled Corrosion Behavior - The invention relates to a stent with a structure of a biocorrodible magnesium alloy or tungsten alloy, which comprises a multiplicity of web sections connected to one another, wherein (i) the structure has a support structure of a number of first web sections connected to one another, which are designed to perform a function supporting the vascular wall or preserving the mechanical integrity of the stent after an expansion of the stent for a predetermined period of time and (ii) at least one second web section is present, which a) is directly connected to a selected first web section, b) does not perform a function supporting the vascular wall or preserving the mechanical integrity of the stent after the expansion of the stent for the predetermined period of time, and c) has a smaller average grain size than the first web sections of the support structure from (i).06-03-2010
20100145432IMPLANT AND METHOD FOR PRODUCING THE SAME - The present invention describes a method for producing an implant, in particular an intraluminal endoprosthesis, wherein the base material of the body (06-10-2010

Bernd Block, Erlangen DE

Patent application numberDescriptionPublished
20110261920CONNECTING DEVICE FOR CONNECTING A GUIDE TUBE TO A LOWER END NOZZLE IN A NUCLEAR FUEL ASSEMBLY - A connecting device including a nut, a screw, a body having a bore for screwing the screw to the nut through the bore with the screw abutting an abutment surface of the body, a screw locking device for preventing loosening of the screw.10-27-2011

Christian Block, Koeln DE

Patent application numberDescriptionPublished
20080312123HOLLOW BODY WITH A COMPARTMENT, CONTAINING A PORTION OF A WASHING, CLEANING OR RINSING AGENT - A process for producing a detergent portion, comprising the steps of forming one or more dimensionally stable hollow bodies comprising at least one compartment by injection moulding, providing one or more means for compartmentalizing the dimensionally stable hollow bodies, filling the compartment with at least one detersive formulation, and closing the compartment to form a partial or whole enclosure around the detersive formulation.12-18-2008

Christoph Block, Münster DE

Patent application numberDescriptionPublished
20090163370Competitive N-Hybrid System - The invention relates to a method for identifying highly affinous ligands comprising the following steps: a) creating a bank for a mutagenized first hybrid protein comprising a plurality of mutants; b) expression of a first hybrid protein in a host with a second hybrid protein, one of the hybrid proteins comprising the DNA binding domain of a transcription factor and a bait protein and the other hybrid protein comprising the activation domain for a transcription factor and a prey protein; c) allowing the binding reaction between the first and second hybrid protein in order to form a complex with a functional transcription factor in the host cell under reaction conditions, which are such that the balance of the binding reaction is offset on the side of the hybrid proteins; d) detecting the binding reaction by detecting a reporter gene expressed via the functional transcription factor; e) optionally repeating one or more steps from a) to d); f) selection of a mutant.06-25-2009

Christoph Block, M¨nster DE

Christoph Block, Datum DE

Patent application numberDescriptionPublished
20090239935RNA-HELICASE AS A MARKER FOR RARE TUMORS - Method for the diagnosis of diseases in a mammal, preferably in a human, wherein a probe from the mammal is examined with a view to an elevated level of RNA helicase and the elevated level of RNA helicase indicates the disease. The disease refers to esophagus carcinoma, pancreas carcinoma, stomach carcinoma, hepatocellular carcinoma, hepatoblastoma and cholangiocellular carcinoma.09-24-2009

Christoph Block, Munster DE

Patent application numberDescriptionPublished
20090163370Competitive N-Hybrid System - The invention relates to a method for identifying highly affinous ligands comprising the following steps: a) creating a bank for a mutagenized first hybrid protein comprising a plurality of mutants; b) expression of a first hybrid protein in a host with a second hybrid protein, one of the hybrid proteins comprising the DNA binding domain of a transcription factor and a bait protein and the other hybrid protein comprising the activation domain for a transcription factor and a prey protein; c) allowing the binding reaction between the first and second hybrid protein in order to form a complex with a functional transcription factor in the host cell under reaction conditions, which are such that the balance of the binding reaction is offset on the side of the hybrid proteins; d) detecting the binding reaction by detecting a reporter gene expressed via the functional transcription factor; e) optionally repeating one or more steps from a) to d); f) selection of a mutant.06-25-2009
20100297772METHOD FOR THE CREATION OF GENETIC DIVERSITY IN VIVO - Disclosed is a method for creating genetic diversity in vivo, comprising the following steps: fragments of at least one wild-type gene sequence are produced, each of said fragments being provided with at least one region which is homologous with a vector that is suitable for in vivo recombination; randomized bridging oligonucleotides of at least one defined oligonucleotide sequence are produced, parts of the bridging oligonucleotide being homologous with at least one fragment of the wild-type gene sequence; and the linearized vector, at least one wild-type fragment, and the randomized bridging oligonucleotide/s are introduced into an in vivo system for homologous recombination.11-25-2010
20110110856Optimized Adhesin Fragments And Corresponding Nanoparticles - The invention relates to optimized adhesins and nanoparticles to which said adhesins are bound. The invention furthermore relates to providing said nanoparticles by way of in vivo contrast agents, in particular for the diagnosis of bowel cancer.05-12-2011
20110237451COMPETITIVE N-HYBRID SYSTEM - A method of identifying high-affinity ligands, comprising the following steps: 09-29-2011

Patent applications by Christoph Block, Munster DE

Dirk Block, Bichl DE

Patent application numberDescriptionPublished
20100285491USE OF IGFBP-7 IN THE ASSESSMENT OF HEART FAILURE - The invention relates to a method for assessing heart failure in vitro comprising the steps of measuring in a sample the concentration of the marker IGFBP-7, of optionally measuring in the sample the concentration of one or more other marker(s) of heart failure, and of assessing heart failure by comparing the concentration determined in for IGFBP-7 and the concentration(s) determined for the optionally one or more other marker to the concentration of this marker or these markers as established in a reference population. Also disclosed are the use of IGFBP-7 as a marker protein in the assessment of heart failure, a marker combination comprising IGFBP-7 and a kit for measuring IGFBP-7.11-11-2010
20100285492USE OF SLIM-1 IN THE ASSESSMENT OF HEART FAILURE - The invention relates to a method for assessing heart failure in vitro comprising the steps of measuring in a sample the concentration of the marker SLIM-1, of optionally measuring in the sample the concentration of one or more other marker(s) of heart failure, and of assessing heart failure by comparing the concentration determined in for SLIM-1 and the concentration(s) determined for the optionally one or more other marker to the concentration of this marker or these markers as established in a reference population. Also disclosed are the use of SLIM-1 as a marker protein in the assessment of heart failure, a marker combination comprising SLIM-1 and a kit for measuring SLIM-1.11-11-2010
20110027819USE OF SFRP-3 IN THE ASSESSMENT OF HEART FAILURE - Disclosed is a method for assessing heart failure in vitro including the steps of measuring in a sample the concentration of the marker SFRP-3, of optionally measuring in the sample the concentration of one or more other marker(s) of heart failure, and of assessing heart failure by comparing the concentration determined in for SFRP-3 and the concentration(s) determined for the optionally one or more other marker to the concentration of this marker or these markers as established in a reference population. Also disclosed are the use of SFRP-3 as a marker protein in the assessment of heart failure, a marker combination comprising SFRP-3 and a kit for measuring SFRP-3.02-03-2011
20110137020Method and Device for Purifying Nucleic Acids - The invention concerns a method for isolating and purifying nucleic acids from a sample and a device that is suitable therefore.06-09-2011
20110165591USE OF BIGLYCAN IN THE ASSESSMENT OF HEART FAILURE - The invention relates to a method for assessing heart failure in vitro and involves the steps of measuring in a sample the concentration of the marker biglycan, of optionally measuring in the sample the concentration of one or more other marker(s) of heart failure, and of assessing heart failure by comparing the concentration determined in for biglycan and the concentration(s) determined for the optionally one or more other marker to the concentration of this marker or these markers as established in a reference population. Also disclosed are the use of biglycan as a marker protein in the assessment of heart failure, a marker combination comprising biglycan and a kit for measuring biglycan.07-07-2011

Patent applications by Dirk Block, Bichl DE

Ditmar Block, Koln DE

Patent application numberDescriptionPublished
20100212320METHOD FOR OPERATING A STEAM TURBINE POWER PLANT AND ALSO DEVICE FOR GENERATING STEAM - The invention refers to a method for operating a steam turbine power plant, and also a device for generating steam for the purpose of power generation.08-26-2010

Hans-Ulrich Block, Munchen DE

Patent application numberDescriptionPublished
20100161331Method for Preparing Information for a Speech Dialogue System - In many application environments, it is desirable to provide voice access to tables on Internet pages, where the user asks a subject-related question in a natural language and receives an adequate answer from the table read out to him in a natural language. A method is disclosed for preparing information presented in a tabular form for a speech dialogue system so that the information of the table can be consulted in a user dialogue in a targeted manner.06-24-2010
20100267345Method and System for Preparing Speech Dialogue Applications - A server for producing at least one speech dialogue application stores a formal description of a speech dialogue programmed into the description language and speech models for dialogue steps of the speech dialogue. A broadcasting transmitter digitally transmits produced speech dialogue applications to a radio set of mobile end terminals which are arranged in the transmission area thereof.10-21-2010

Helena Block, Hilden DE

Patent application numberDescriptionPublished
20110163255METHOD FOR PROTEIN PURIFICATION UNDER DENATURING CONDITIONS - The invention relates to a method for the preparation of an application buffer for the purification of proteins by means of immobilized metal ion affinity chromatography (IMAC) under denaturing conditions, which is characterized in that a defined amount of a buffer concentrate having a defined pH value is mixed with a defined amount of a urea concentrate, whereby an application buffer having a defined pH value is provided. According to the invention, a corresponding kit is provided in addition. The components are stable in storage and by mixing produce an application buffer having a defined composition and a defined pH value. The need for pH adjustment or a new preparation is eliminated. The invention can thus be used in an automated manner and as a closed kit concept.07-07-2011

Kai Tobias Block, Nuernberg DE

Patent application numberDescriptionPublished
20110234228MAGNETIC RESONANCE SYSTEM AND METHOD TO CREATE A MAGNETIC RESONANCE IMAGE DATA SET BY RADIAL SCANNING OF A MAGNETIC RESONANCE SYSTEM - In a magnetic resonance apparatus and method to generate an image data set by means of a radial scanning of a raw data set, at least one calibration measurement is implemented for at least one predetermined spoke of the radial scan, and a gradient moment difference between an assumed gradient moment and an actually applied gradient moment is determined along the at least one predetermined spoke. Readout of all spokes of the predetermined raw data set ensues by activating multiple magnetic field gradients in spatial directions in order to respectively read out scan points of a respective spoke. The position of each scan point of each spoke is corrected depending on the gradient moment difference, by the position of the respective scan point that is assumed based on the respective activated magnetic field gradients being shifted by the gradient moment difference.09-29-2011

Lutz-Henning Block, Emmendingen DE

Patent application numberDescriptionPublished
20080221041Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension - The present invention relates to peptides which are highly biologically and pharmacologically active as therapeutic drug for the treatment of diseases related to hypertension, especially in medical interventions involving dilatation and remodeling of arterial blood vessels, either in the pulmonary or in the systemic circulation. The peptides which can be used according to the invention for the treatment of said diseases comprise at least one specific highly conservative amino acid residue sequence which seem to play an important role in connection with pulmonary and arteriolar hypertension events. It could be shown that the known naturally occurring peptides “vasoactive intestinal peptide (VIP)” and “pituitary adenylate cyclase-activating polypeptide (PACAP)”, having these specific sequences are potent drugs which can be successfully used for treatment of primary pulmonary hypertension (PPH), secondary pulmonary hypertension (SPH), and hypertension of the systemic circulation. Furthermore, the present invention discloses pharmaceutical compositions useful for treatment of PPH, SPH, and hypertension of the systemic circulation within said methods.09-11-2008

Marco Balbo Block, Osnabruck DE

Patent application numberDescriptionPublished
20110251297WATER-BLOWN RIGID FOAMS WITH IMPROVED MECHANICAL PROPERTIES AT LOW TEMPERATURES - The present invention relates to a rigid polyurethane foam which can be obtained by mixing (a) isocyanates, (b) compounds having groups which are reactive toward isocyanates, (c) blowing agents comprising water, (d) catalysts and optionally (e) further additives to form a reaction mixture, applying the reaction mixture to a reinforcing material and curing the reaction mixture, where the isocyanates (a) have a viscosity of not more than 500 mPas at 25° C. and the compounds (b) having groups which are reactive toward isocyanates comprise a polyetherol (b1) having a functionality of 4 or more and a viscosity at 25° C. of 10 000 mPas or less, a polyetherol (b2) having a functionality of 3.5 or less and a viscosity at 25° C. of 600 mPas or less, a polyesterol (b3) having a viscosity at 25° C. of 2000 mPas or less, chain extenders (b4) comprising at least 30% secondary OH groups and optionally a crosslinker (b5). The present invention further relates to a process for producing such rigid polyurethane foams and the use of the rigid polyurethane foams for the insulation of liquefied natural gas tanks.10-13-2011

Martina Block, Bonn DE

Patent application numberDescriptionPublished
20090263554Nucleic acid molecules encoding enzymes from wheat which are involved in starch synthesis - The present invention relates to nucleic acid molecules encoding enzymes which are involved in the starch synthesis in plants. These enzymes are starch synthases from wheat.10-22-2009

Meinolf Block, Heidelberg DE

Patent application numberDescriptionPublished
20110282914INTEGRATED APPLICATION SERVER AND DATA SERVER PROCESSES WITH MATCHING DATA FORMATS - In one embodiment, the present invention includes a computer-implemented method comprising storing data in an application using an application custom data type and application custom data structure. The data is stored in a database using the application custom data type and the application custom data structure. In one embodiment, a request is sent to access the data from the application to the database. The data is retrieved from the database in response to the request in the application custom data type and the application custom data structure. In one embodiment, the data is sent from the database to a shared memory in the application custom data type and the application custom data structure and the data is retrieved by the application from the shared memory in the application custom data type and the application custom data structure.11-17-2011

Oliver Block, Rossdorf DE

Patent application numberDescriptionPublished
20100311976PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES - The invention relates to a novel process for preparing enantiomerically enriched or pure tetrahydroquinoline derivatives by reacting a chiral dihydropyran-methylamine C with a aldehyde B and an aniline A in a multicomponent one pot synthesis in the presence of a protonic acid or Lewis acid with a suitable solvent. A, B, C have the meaning as described in the specification.12-09-2010

Sebastian Block, Memmelsdorf DE

Patent application numberDescriptionPublished
20100292036TENSIONING DEVICE FOR THE TRACTION MECHANISM DRIVE IN A TIMING SYSTEM ON A MOTOR VEHICLE - A tensioning device for the endless drive in a timing system on a motor vehicle, which has a tensioning piston that can move along a path axis in a housing, within which a pressure chamber is located which houses a working medium which brings about a movement of the tensioning piston in the housing and has a valve seat, connected to the exterior of the tensioning piston by an outlet and accommodating a valve body essentially matching the shape of the valve seat. The valve body is tapered along the axial path axis to the outlet, which allows for a large chamber between the valve body and the valve seat. The path that the working medium, on bleeding gas bubbles from the same, takes from the pressure chamber to the outlet is longer, which increases the hydraulic resistance and restricts and limits emptying of working medium from the tensioning piston.11-18-2010

Thomas Block, Wuppertal DE

Patent application numberDescriptionPublished
20090300239USB Connection - In the case of a universal serial bus (USB) connection, a host detects a connection of a peripheral to the host via a USB interface of the host. The host then generates an informative command, which includes information on capabilities of the host. This informative command is provided for transmission via the USB interface to the peripheral. The peripheral receives the informative command and may for instance evaluate the included information for selecting a suitable USB mode that is to be entered or for deciding on becoming a host itself. Alternatively or in addition, the host may generate a request command for retrieving information on all classes offered in all USB modes of a peripheral.12-03-2009
20100037074POWER CONTROL FOR SERIAL BUS PERIPHERAL DEVICE - There is disclosed a method and a device connected to a serial bus, said method comprising transmitting a message that indicates a power requirement for a suspended mode of said serial bus; in response to a received authorization message, setting a first or a second operating state; entering said suspended mode; drawing a current in accordance with said indicated power requirement that may exceed a predetermined current limit if said operating state is said first state, and drawing a current at or below said predetermined current limit if said operating state is said second state.02-11-2010
20100040041SWITCHING ROLE OF APPARATUSES BETWEEN CONTROLLER (HOST) AND PARTICIPANT (DEVICE) TO SCHEDULE BI-DIRECTIONAL DATA - A method involving: sending from a first apparatus to a second apparatus a first message identifying the first apparatus and a second message scheduling a time period for reply; receiving at the first apparatus during the time period scheduled by the second message a third message sent by the second apparatus; and in response to receiving the third message, changing a role of the first apparatus so that it is operable to schedule bi-directional data transfer between the first apparatus and the second apparatus.02-18-2010

Patent applications by Thomas Block, Wuppertal DE

Torsten Block, Nufringen DE

Patent application numberDescriptionPublished
20100147215ELECTROSTATIC SPRAYING ARRANGEMENT - A transformer arrangement is disclosed for an electrostatic sprayer or in an adjacent moving element of a coating machine. A transformer provides a galvanic isolation between the line arrangement provided for supplying power to the sprayer arrangement, and consumers at high voltage in the sprayer or possibly in the robot arm. This isolation may be provided with an isolating transformer which has a sufficient isolation distance or other isolation device between the primary and secondary circuits.06-17-2010
20100211205METHOD FOR PROCESS DIAGNOSIS AND ROTARY ATOMIZER ARRANGEMENT - A rotary atomizer arrangement and methods for operating the same are disclosed. An exemplary atomizer may be used for the coating of work pieces, and may include a bell plate driven by an electric motor. The exemplary atomizer may further be configured for the detection of errors in the spraying process and/or the drive system of the bell plate, such as by analyzing corresponding parameters of typical values of the drive motor.08-19-2010
20110159196COATING DEVICE AND COATING METHOD HAVING A CONSTANT DIRECTING AIR TEMPERATURE - Exemplary coating devices and methods are disclosed. An exemplary coating device may include an atomizer for applying a spray jet of a coating means or material to a component, at least one directing air nozzle for outputting shaping or directing air in order to shape the spray jet, and a temperature-control device for controlling the temperature of the directing air. The coating device may further include a control unit which activates the temperature-control device as a function of at least one operating variable of the atomizer in order to set a predetermined directing air temperature.06-30-2011

Volker Block, Bretten DE

Patent application numberDescriptionPublished
20100083845STEAM GENERATOR COOKING DEVICE METHOD FOR OPERATING AND PRODUCING A STEAM GENERATOR AND METHOD FOR COOLING A HEATING DEVICE - A steam generator for cooking devices has a vessel and a heating device. Water to be evaporated is contained within a free volume of an inner chamber of the vessel, which forms a water-guiding region. This water is heated through a heating device at least up to boiling temperature, whereby steam is generated that flows along a steam-guiding region of the vessel. The heating device is a thick-film heating device applied to the surface area of the vessel on the water-guiding region. Both the water and the steam flowing past cool the heating device as the water level drops.04-08-2010
20100263137METHOD FOR OPERATING A WASHING MACHINE HAVING A HEATING UNIT - The invention in one embodiment relates to a method for operating a washing machine having a heating unit, wherein the heating unit comprises a carrier and at least one planar heating element disposed thereon. At least one first heating element is attached to the carrier in a planar manner, wherein the carrier has a recess extending in the longitudinal direction in the center region. The washing machine has a washing machine barrel and a drum therein, wherein the heating unit is displaced at the bottom in the washing machine barrel outside of the drum. A heating element is provided on the outside of the carrier in the region of the recess in the region along an apex, or along an apex of the recess, wherein only said heating element is operated in the region of the recess for creating steam in the washing machine.10-21-2010

Wolfgang Block, Wermelskirchen DE

Patent application numberDescriptionPublished
20100077562DOUBLE ROLLER WITH TWO RUNNING WHEELS AND ROLLER WITH ONE RUNNING WHEEL - The invention relates to a double roller (04-01-2010
20100181122Hospital Bed With a Further Auxiliary Roller That Can Be Brought Into Contact With the Floor or Can Alternatively Be Driven - The invention relates to a hospital bed (07-22-2010
20110232027Swivel caster - A swivel caster has a caster body, a pivot bearing and a foot that can be extended by means of an electric motor. The foot has a telescoping foot part. The electric motor is disposed below the pivot bearing, at least below a first, upper bearing.09-29-2011

Patent applications by Wolfgang Block, Wermelskirchen DE