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Blobel

Carl P. Blobel, New York, NY US

Patent application numberDescriptionPublished
20090285840METHODS FOR TREATING PATHOLOGICAL NEOVASCULARIZATION - Provided herein are compositions and methods that inhibit expression of Adam9 gene products, such as ADAM9 mRNA and/or ADAM9 polypeptides, as a therapeutic approach for the treatment of pathological neovascularization and conditions associated with angiogenesis.11-19-2009

Carl Peter Blobel, Eastchester, NY US

Patent application numberDescriptionPublished
20090068251METHODS AND COMPOSITIONS FOR PROMOTING WOUND HEALING - Provided herein are compositions and methods that inhibit expression of Adam12 gene products, such as ADAM12 mRNA and/or ADAM12 polypeptides, as a therapeutic approach for the treatment of, or promotion of healing of, wounds.03-12-2009

Gunter Blobel, New York, NY US

Patent application numberDescriptionPublished
20100212040ISOLATION OF LIVING CELLS AND PREPARATION OF CELL LINES BASED ON DETECTION AND QUANTIFICATION OF PRESELECTED CELLULAR RIBONUCLEIC ACID SEQUENCES - The invention is directed to reliable and efficient detection of mRNAs as well as other RNAs in living cells and its use to identify and, if desired, separate cells based on their desired characteristics. Such methods greatly simplify and reduce the time necessary to carry out previously-known procedures, and offers new approaches as well, such as selecting cells that generate a particular protein or antisense oligonucleotide, generating cell lines that express multiple proteins, generating cell lines with knock-out of one or more protein, and others.08-19-2010

Joerg Blobel, Zoetermeer NL

Patent application numberDescriptionPublished
20110129057METHOD FOR DETERMING A CORRECTION FUNCTION FOR CORRECTING COMPUTED TOMOGRAPHIC NUMBERS OF A SMALL TARGET OBJECT IN A CT IMAGE - A method of correcting target region in computed tomographic (CT) image, including the steps of obtaining a CT image of a patient; determining the size of a target object in the CT image; and correcting CT numbers of a portion of the CT image that corresponds to the target object, based on the determined size of the target object.06-02-2011

Lars Blobel, Ammerbuch-Entringen DE

Patent application numberDescriptionPublished
20100217073ELECTROSURGICAL INSTRUMENT, AND AN ENDOSCOPE WITH A CORRESPONDING INSTRUMENT - An electrosurgical instrument including a protective tube, to be inserted into a working channel of an endoscope, and an electrode disposed within the protective tube. The electrode is movable in a distal direction and a proximal direction inside the protective tube by a control element. By being moved in the distal direction, the electrode can be brought into a deployed position in which the electrode at least partially protrudes from a distal end of the protective tube. The distal end of the protective tube has a closure element with an opening for the passage of the electrode. The opening of the closure element has a maximum internal diameter smaller than the internal diameter of the protective tube and is used for guiding and/or cleaning the electrode.08-26-2010
20100262141SURGICAL INSTRUMENT FOR SEALING BLOOD VESSELS, AND HEAT-CURABLE ADHESIVE AS A MEDICAMENT - A surgical instrument including an injection device and a dosing device. These devices are designed such that a predetermined amount of an adhesive or an adhesive containing filler can be injected into a sealing section of the blood vessel. The blood vessel can then be cut at the filled point and is sealed on both sides.10-14-2010
20110028887WATER JET SURGICAL INSTRUMENT - A water jet surgical instrument including a supply line for supplying a cutting fluid and a discharge nozzle for forming and discharging a fluid jet, wherein the fluid jet has a predetermined spread angle and/or a predetermined emergence energy. A jet shaping device is arranged relative to the discharge nozzle such that the fluid jet is able to be adjusted by the jet shaping device with regard to the spread angle and/or emergence energy thereof.02-03-2011
20110071427CRYOSURGICAL INSTRUMENT FOR OBTAINING A TISSUE SAMPLE, METHOD FOR CHILLING A PROBE HEAD OF A CRYOSURGICAL PROBE - A cryosurgical instrument for obtaining a tissue sample with a probe, including the probe including a probe head onto which the tissue sample is frozen and a probe shank for guiding the probe head to the tissue sample, a supply means for supplying a fluid into an expansion chamber configured such that supplied fluid expands therein for cooling the probe head, and a removal means connected to the expansion chamber for removing the expanded fluid therefrom via at least one opening on a distal end of the probe to remove the expanded fluid to an outer region outside the probe. A method for cooling a probe head of a cryosurgical probe including supplying a fluid to an expansion chamber near the probe head, expanding the fluid so that heat energy is withdrawn from the probe head, and removing the expanded fluid in a distal region of the probe.03-24-2011