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Blight, US

Andrew R. Blight, Mahopac, NY US

Patent application numberDescriptionPublished
20090150180Method, apparatus and solftware for identifying responders in clinical environment - A process for determining responders in clinical testing environments that involves, inter alia, detecting treatment response through the use of small numbers of measurements of randomly varying outcome variables in individual clinical trial subjects, and by analyzing the measurements in such a way as to eliminate troublesome variables, such as a spontaneous population variability.06-11-2009
20100061935METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS - Disclosed herein are methods and compositions related to use of aminopyridines, such as fampridine, to improve impairments of patients with a demyelinating condition, such as MS.03-11-2010
20100324098SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS - A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at least 12 hours, preferably 24 hours or more and the use of the composition to treat various neurological diseases.12-23-2010
20100324099SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS - A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at least 12 hours, preferably 24 hours or more and the use of the composition to treat various neurological diseases.12-23-2010
20100324100SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS - A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at least 12 hours, preferably 24 hours or more and the use of the composition to treat various neurological diseases.12-23-2010
20110166187METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS - A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at about 12 hours and the use of the composition to treat various neurological diseases, including multiple sclerosis. A method of selecting individuals based on responsiveness to a treatment, including, for example, identifying individuals who responded to treatment with a sustained release fampridine composition.07-07-2011
20110166188METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS - A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at about 12 hours and the use of the composition to treat various neurological diseases, including multiple sclerosis. A method of selecting individuals based on responsiveness to a treatment, including, for example, identifying individuals who responded to treatment with a sustained release fampridine composition.07-07-2011
20110166189METHODS OF USING SUSTAINED RELEASE AMINOPYRIDINE COMPOSITIONS - A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at about 12 hours and the use of the composition to treat various neurological diseases, including multiple sclerosis. A method of selecting individuals based on responsiveness to a treatment, including, for example, identifying individuals who responded to treatment with a sustained release fampridine composition.07-07-2011

Patent applications by Andrew R. Blight, Mahopac, NY US

David Blight, Santa Clara, CA US

Patent application numberDescriptionPublished
20100144272SYSTEM AND METHOD FOR LOCATING AND ACCESSING WIRELESS RESOURCES - A system and method are disclosed for locating resources available to portable electronic devices which are enabled for short range wireless communications. The system and method include creating and accessing a resource and access location history database accessible via the portable electronic device.06-10-2010

David C. Blight, Oceanside, CA US

Patent application numberDescriptionPublished
20090319575INDIVIDUALIZING AND ENCRYPTING ON-DEMAND MEDIA CONTENT IN RETAIL KIOSKS - A system for selecting and recording data, comprising: a local storage unit for storing a subset of media content items and other content; a content selection unit to display a catalog of the media content items and other content, to allow a customer to browse, search, and select a media content item and other content from the catalog of media content items and other content, to retrieve the selected media content item and other content from the local storage unit if the selected media content item and other content is found in the subset, and otherwise to retrieve the selected media content item from a remote storage unit, the content selection unit configured to cache the retrieved media content item and other content in the local storage unit for a period of time based on the popularity of the retrieved media content item; a financial transaction unit to determine the cost of the retrieved media content item and other content and display the cost for review and payment by the customer; and an authoring system configured to format, encode, encrypt, and write the media content item and other content onto an article of media when the customer makes the payment.12-24-2009
20100121930MESSAGING SERVER TO REDIRECT AN INSTANT MESSAGE TO A MOBILE DEVICE - A messaging server is configured to receive an instant message comprising a message address and to store a mobile device ID associated with the message address. The messaging server is configured to redirect the instant message to a mobile device associated with the mobile device ID and to send the instant message to the mobile device.05-13-2010

Patent applications by David C. Blight, Oceanside, CA US

Keril J. Blight, St. Louis, MO US

Patent application numberDescriptionPublished
20080213750HCV Variants and Related Methods - HCV variants are described. The variants include polynucleotides comprising non-naturally occurring HCV sequences and HCV variants that have a transfection efficiency and ability to survive subpassage greater than HCV that have wild-type polyprotein coding regions. Expression vectors comprising the above polynucleotides and HCV variants are also described, as are the provision of cells and host cells comprising the expression vectors. Methods for identifying a cell line that is permissive for infection with HCV are also provided, as are vaccines comprising the above polynucleotides in a pharmaceutically acceptable carrier. Additionally, methods for inducing immunoprotection to HCV in a primate are described, as are methods for testing a compound for inhibiting HCV replication.09-04-2008