Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Blanche
Emilie Blanche, Heverlee BE
| Patent application number | Description | Published |
|---|---|---|
| 20110224208 | NOVEL INHIBITORS OF FLAVIVIRUS REPLICATION - The present invention relates to a series of Isoquinolone derivatives which are suitable to treat infections with viruses belonging to the family of the Flaviviridae and more preferably infections with Hepatitis C virus (HCV). The present invention also relates to Isoquinolone compounds for use as a medicine for the prevention or treatment of viral infections, preferably infections with viruses belonging to the family of the Flaviviridae. | 09-15-2011 |
Francis Blanche, Paris FR
| Patent application number | Description | Published |
|---|---|---|
| 20100010208 | PURIFICATION OF A TRIPLE HELIX FORMATION WITH AN IMMOBILIZED OLIGONUCLEOTIDE - Method for double-stranded DNA purification, by which a solution containing said DNA in a mixture with other components is passed over a support on which is covalently coupled in oligonucleotide capable of hybridizing with a specific sequence present on said DNA to form a triple helix. | 01-14-2010 |
| 20100061979 | MODIFIED SOLUBLE FGF RECEPTOR FC FUSIONS WSITH IMPROVED BIOLOGICAL ACTIVITY - The invention relates to modified soluble FGF receptor Fc fusions comprising a fusion of a soluble fragment or domain of the FGF receptor part (targeting or binding moiety) with an Fc region of an immunoglobulin part (effector function moiety), having improved biological activity including ADCC/CDC activities, compositions containing them, and method of producing such modified soluble FGF receptor Fc fusion molecules. | 03-11-2010 |
| 20110150903 | FGF-R4 RECEPTOR-SPECIFIC ANTAGONISTS - The present invention relates to FGF-R4 receptor-specific antagonist molecules enabling the inhibition of the activity of said receptor. Said antagonists are, particularly, FGF-R4-specific antibodies enabling the inhibition of the activity of said receptor. The present invention also relates to the therapeutic use of said antibodies, particularly in the field of angiogenesis and in the treatment of certain types of cancer. | 06-23-2011 |
Françis Blanche, Paris FR
| Patent application number | Description | Published |
|---|---|---|
| 20100010208 | PURIFICATION OF A TRIPLE HELIX FORMATION WITH AN IMMOBILIZED OLIGONUCLEOTIDE - Method for double-stranded DNA purification, by which a solution containing said DNA in a mixture with other components is passed over a support on which is covalently coupled in oligonucleotide capable of hybridizing with a specific sequence present on said DNA to form a triple helix. | 01-14-2010 |
Patricia J. Blanche, Berkeley, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080305549 | LIPOPROTEIN ANALYSIS BY DIFFERENTIAL CHARGED-PARTICLE MOBILITY - The invention provides methods of preparation of lipoproteins from a biological sample, including HDL, LDL, Lp(a), IDL, and VLDL, for diagnostic purposes utilizing differential charged particle mobility analysis methods. Further provided are methods for analyzing the size distribution of lipoproteins by differential charged particle mobility, which lipoproteins are prepared by methods of the invention. Further provided are methods for assessing lipid-related health risk, cardiovascular condition, risk of cardiovascular disease, and responsiveness to a therapeutic intervention, which methods utilize lipoprotein size distributions determined by methods of the invention. | 12-11-2008 |
| 20100213061 | ION MOBILITY ANALYSIS OF LIPOPROTEINS - A medical diagnostic method and instrumentation system for analyzing noncovalently bonded agglomerated biological particles is described. The method and system comprises: a method of preparation for the biological particles; an electrospray generator; an alpha particle radiation source; a differential mobility analyzer; a particle counter; and data acquisition and analysis means. The medical device is useful for the assessment of human diseases, such as cardiac disease risk and hyperlipidemia, by rapid quantitative analysis of lipoprotein fraction densities. Initially, purification procedures are described to reduce an initial blood sample to an analytical input to the instrument. The measured sizes from the analytical sample are correlated with densities, resulting in a spectrum of lipoprotein densities. The lipoprotein density distribution can then be used to characterize cardiac and other lipid-related health risks. | 08-26-2010 |
| 20110089037 | BIOLOGICAL PARTICLES - A medical diagnostic method and instrumentation system for analyzing noncovalently bonded agglomerated biological particles is described. The method and system comprises: a method of preparation for the biological particles; an electrospray generator; an alpha particle radiation source; a differential mobility analyzer; a particle counter; and data acquisition and analysis means. The medical device is useful for the assessment of human diseases, such as cardiac disease risk and hyperlipidemia, by rapid quantitative analysis of lipoprotein fraction densities. Initially, purification procedures are described to reduce an initial blood sample to an analytical input to the instrument. The measured sizes from the analytical sample are correlated with densities, resulting in a spectrum of lipoprotein densities. The lipoprotein density distribution can then be used to characterize cardiac and other lipid-related health risks. | 04-21-2011 |
Pierre-Alexandre Jean Blanche, Tucson, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20090046333 | System and Method Using a Voltage Kick-Off to Record a Hologram on a Photorefractive Polymer for 3D Holographic Display and Other Applications - An updateable system and method of recording a hologram on a media simultaneously reduces the writing time and increases persistence without sacrificing diffraction efficiency. A voltage kick-off technique controls the bias electric field applied to a photorefractive polymer media in conjunction with the application of the writing beams and dark decay. Essentially the voltage kick-off technique applies a high electric field above the optimal field while the writing beams are on and reduces the electric field when the writing beams are off during dark decay. The voltage kick-off technique produced two separate unexpected results. First, when the writing beams are turned off and the electric field is lowered the diffraction efficiency continues to increase until it reaches a maximum efficiency that is within a few percent of that achieved by writing at the optimal field until steady-state is achieved. Second, the decay time constant is much larger than expected producing a much longer persistence without sacrificing diffraction efficiency or writing time. | 02-19-2009 |
| 20110199658 | System and method for synchronizing a spatial light modulator with a pulsed laser to record a hologram at the repetition rate of the pulsed laser - A system and method that synchronizes a spatial light modulator (SLM) with a pulsed laser to record a hologram at the repetition rate of the pulsed laser for applications including holographic displays and data storage. The color channel capability of a SLM is utilized to effectively increase the write throughput when the pulsed laser repetition rate LR exceeds the SLM's image refresh rate R. The hogels are encoded on the color channels and concatenated to form a sequence of color images such that the write throughput is equal to the repetition rate LR up to a maximum of N*R. The invention effectively extends the capability and continued viability of existing inexpensive SLMs. | 08-18-2011 |