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Blakey, GB
David C. Blakey, Macclesfield Cheshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20080267971 | Antibodies Directed to Angiopoietin-2 and Uses Thereof - Antibodies directed to the antigen Ang-2 and uses of such antibodies are described. In particular, fully human monoclonal antibodies directed to the antigen Ang-2. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementary determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3. Hybridomas or other cell lines expressing such immunoglobin molecules and monoclonal antibodies. | 10-30-2008 |
David Charles Blakey, Cheshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20090324601 | TARGETED BINDING AGENTS DIRECTED TO PDGFR-ALPHA AND USES THEREOF - Targeted binding agents directed to the antigen PDGFR-alpha and uses of such agents are disclosed herein. More specifically the invention relates to fully human monoclonal antibodies directed to the antigen PDGFR-alpha and uses of these antibodies. Aspects of the invention also relate to hybridomas or other cell lines expressing such antibodies. The described targeted binding agents and antibodies are useful as diagnostics and for the treatment of diseases associated with the activity and/or overexpression of PDGFR-alpha. | 12-31-2009 |
David Charles Blakey, Macclesfield GB
| Patent application number | Description | Published |
|---|---|---|
| 20090123474 | COMBINATION OF ANGIOPOIETIN-2 ANTAGONIST AND OF VEGF-A, KDR AND/OR FLTL ANTAGONIST FOR TREATING CANCER - The invention relates to agents which possess anti-angiogenic activity and are accordingly useful in methods of treatment of disease states associated with angiogenesis in the animal or human body. More specifically the invention concerns a combination of an antagonist of the biological activity of Angiopoietin-2 and an antagonist of the biological activity of VEGF-A, and/or KDR, and/or Flt1, and uses of such antagonists. | 05-14-2009 |
| 20110020360 | TARGETED BINDING AGENTS DIRECTED TO PDGRF-ALPHA AND USES THEREOF - Targeted binding agents directed to the antigen PDGFR-alpha and uses of such agents are disclosed herein. More specifically the invention relates to fully human monoclonal antibodies directed to the antigen PDGFR-alpha and uses of these antibodies. Aspects of the invention also relate to hybridomas or other cell lines expressing such antibodies. The described targeted binding agents and antibodies are useful as diagnostics and for the treatment of diseases associated with the activity and/or overexpression of PDGFR-alpha. | 01-27-2011 |
| 20110097321 | COMBINATION OF ANGIOPOIETIN-2 ANTAGONIST AND OF VEGF-A, KDR AND/OR FLT1 ANTAGONIST FOR TREATING CANCER - The invention relates to agents which possess anti-angiogenic activity and are accordingly useful in methods of treatment of disease states associated with angiogenesis in the animal or human body. More specifically the invention concerns a combination of an antagonist of the biological activity of Angiopoietin-2 and an antagonist of the biological activity of VEGF-A, and/or KDR, and/or Flt1, and uses of such antagonists. | 04-28-2011 |
David Clarles Blakey, Cheshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20110129412 | Antibodies Directed to CD20 and Uses Thereof - Antibodies directed to the antigen CD20 and uses of such antibodies are disclosed herein. In particular, fully human monoclonal antibodies directed to the antigen CD20. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3 are disclosed. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies are also disclosed. | 06-02-2011 |
David M. Blakey, Bishop'S Stortford GB
| Patent application number | Description | Published |
|---|---|---|
| 20080254340 | BATTERY HAVING FLUID REGULATOR WITH PRESSURE EQUALIZATION - A fluid consuming battery ( | 10-16-2008 |
| 20080254346 | BATTERY HAVING FLUID REGULATOR WITH ROTATING VALVE - A fluid consuming battery ( | 10-16-2008 |
David Mark Blakey, Hertfordshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20110081267 | PUMP - A fluid pump comprising a chamber which, in use, contains a fluid to be pumped, the chamber including a main cavity having a substantially cylindrical shape bounded by first and second end walls and a side wall and a secondary cavity extending radially outwards of the main cavity, one or more actuators which, in use, cause oscillatory motion of the first end wall in a direction substantially perpendicular to the plane of the first end wall, and whereby, in use, the axial oscillations of the end walls drive radial oscillations of the fluid pressure in the main cavity, and wherein the secondary cavity spaces the side wall from the first end wall such that the first end wall can move relative to the side wall when the actuator is activated. | 04-07-2011 |
David Mark Blakey, Herts GB
| Patent application number | Description | Published |
|---|---|---|
| 20090087323 | Pump - A fluid pump comprising one or more actuators, two end walls, a side wall; a cavity which, in use, contains fluid, the cavity having a substantially cylindrical shape bounded by the end walls and the side walls, at least two apertures through the cavity walls, at least one of which is a valved aperture, wherein the cavity radius, a, and height, h, satisfy the following inequalities: a/h is greater than 1.2; and h | 04-02-2009 |
Edward W. Blakey, Bournemouth GB
| Patent application number | Description | Published |
|---|---|---|
| 20080285042 | System for Finding Integer Solutions - A system and a method for finding integer solutions of equations whose graphs are conic sections. The system provides a physical implementation of a geometric formulation of integer solutions of conic sections. The system includes a first source of waves and an arrangement of a plurality of reflectors to provide a lattice of interference patterns of standing waves in a plane, the lattice representing intersections at integer values. The system also includes a second source of waves and a detector provided along a curve that, with the second source, defines a cone of waves, which intersects with the plane of the lattice to provide a conic section. The detector finds points of intersection of the lattice and the conic section to determine integer solutions of the conic section. The conic section may be y=N/x, in which case the integer solutions provide a factorization into integers of N. | 11-20-2008 |