Patent application number | Description | Published |
20100292288 | CRYSTALLINE FORMS OF (R)-1-{2-[4`- (3-METHOXY-PROPANE-1- SULFONYL)-BIPHENYL-4-YL]-ETHYL}-2-METHYL-PYRROLIDINE, AND COMPOSITIONS, AND METHODS RELATED THERETO - The present invention is directed to novel salts of (R)-1-{2-[4′-(3-methoxy-propane-1-sulfonyl)-biphenyl-4-yl]-ethyl}-2-methyl-pyrrolidine, and crystalline forms, and compositions thereof that modulate the activity of the histamine H3-receptor and are useful in the treatment of histamine H3-receptor associated disorders, such as, cognitive disorders, epilepsy, brain trauma, depression, obesity, disorders of sleep and wakefulness such as narcolepsy, shift-work syndrome, drowsiness as a side effect from a medication, maintenance of vigilance to aid in completion of tasks and the like, cataplexy, hypersomnia, somnolence syndrome, jet lag, sleep apnea and the like, attention deficit hyperactivity disorder (ADHD), schizophrenia, allergies, allergic responses in the upper airway, allergic rhinitis, nasal congestion, pain, dementia, Alzheimer's disease and the like. | 11-18-2010 |
20120225937 | CRYSTALLINE FORMS AND PROCESSES FOR THE PREPARATION OF PG12 RECEPTOR AGONISTS - The present invention relates to salts of 2-(2-((4-(((4-chlorophenyl)(phenyl)-carbamoyloxy)methyl)cyclohexyl)methoxy)acetamido)ethanesulfonic acid (Compound 1) and crystalline forms, solvates and hydrates thereof. The present invention further relates to processes and intermediates useful in the preparation of Compound I and salts, solvates and hydrates thereof. Crystalline forms, salts, solvates and hydrates of the present invention and pharmaceutical compositions thereof are useful in the treatment of for example, pulmonary arterial hypertension (PAH); platelet aggregation; coronary artery disease; myocardial infarction; transient ischemic attack; angina; stroke; ischemia-reperfusion injury; restenosis; atrial fibrillation; blood clot formation; atherothrombosis; asthma or a symptom thereof; a diabetic-related disorder; glaucoma or other disease of the eye with abnormal intraocular pressure; hypertension; inflammation; psoriasis; psoriatic arthritis; rheumatoid arthritis; Crohn's disease; transplant rejection; multiple sclerosis; systemic lupus erythematosus (SLE); ulcerative colitis; atherosclerosis; acne; type I diabetes; type 2 diabetes; sepsis; and chronic obstructive pulmonary disorder (COPD). | 09-06-2012 |
20130158013 | PROCESSES FOR THE PREPARATION OF 5-HT2C RECEPTOR AGONISTS - Processes and intermediates for preparing salts of the 5-HT | 06-20-2013 |
20130310369 | SALTS OF LORCASERIN WITH OPTICALLY ACTIVE ACIDS - Salts of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine with optically active acids, and pharmaceutical compositions comprising them that are useful for, inter alia, weight management. | 11-21-2013 |
20130315994 | MODIFIED-RELEASE DOSAGE FORMS OF 5-HT2C AGONISTS USEFUL FOR WEIGHT MANAGEMENT - The present invention relates to methods for weight management that utilize modified-release dosage forms comprising (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine salts and crystalline forms thereof. The present invention further relates to (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine salts, crystalline forms thereof and modified-release dosage forms comprising them. | 11-28-2013 |
20130317005 | NON-HYGROSCOPIC SALTS OF 5-HT2C AGONISTS - Salts of the 5-HT2C-receptor agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, and dosage forms comprising them that are useful for, inter alia, weight management. | 11-28-2013 |
20140135345 | CRYSTALLINE FORMS AND PROCESSES FOR THE PREPARATION OF CANNABINOID RECEPTOR MODULATORS - The present invention relates to crystalline forms of (1aS,5aS)-2-(4-oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid ((S)-1-hydroxymethyl-2,2-dimethyl-propyl)-amide (Compound 1) and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB | 05-15-2014 |
20140148442 | FAST-DISSOLVE DOSAGE FORMS OF 5-HT2C AGONISTS - Salts of the 5-HT | 05-29-2014 |
20140206649 | CANNABINOID RECEPTOR MODULATORS - Provided are certain methods useful in the treatment of pain comprising administering a compound of Formula Ia and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB | 07-24-2014 |
20140309192 | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO - The present invention relates to compounds of Formula (I) and pharmaceutically acceptable salts, solvates, and hydrates thereof: | 10-16-2014 |
Patent application number | Description | Published |
20090174768 | Construction imaging and archiving method, system and program - The system, method and program are adapted for collecting images of job-site conditions, and plans and specifications. The images are annotated with attributes that relate to the location, time and trades involved and other aspects of the images. Job site images are collected with a camera connected to a portable data collection device. The data collection device is programmed with image attributes for a particular project. Images are also annotated with attributes gathered by sensors, such as GPS position data, moisture sensor information, and direction information. Images with attached attributes are uploaded to a database server and indexed into a relational database. Images can be flagged and determined to be Images for Resolution which triggers automatic notification to the involved parties and follow up to confirm resolution. Authorized participants can access images in near real time, to make funding, insurance and other judgments about the project. Images are archived for safekeeping and long term storage. | 07-09-2009 |
20110261186 | Imaging and Archiving Method, System and Program - A system, method and program adapted for collecting images of job-site conditions, plans and specifications. Images are annotated with attributes that relate to the location, time and trades involved and other aspects of the images. Job site images are collected with a camera connected to a portable data collection device. The portable data collection device is programmed with image attributes for a particular project. Images are also annotated with attributes gathered by sensors, such as GPS position data and direction information. Images with attached attributes are uploaded to a database server and indexed into a relational database. Images can be flagged and determined to be images for review which triggers automatic notification to the involved parties and follow up to confirm resolution. Authorized participants can access images in near real time, to make funding, insurance and other judgments about the project. Images are archived for safekeeping and long-term storage. | 10-27-2011 |
20120290343 | Work Order Audit System - A system for auditing and analyzing work performed by other individuals is disclosed. Data is imported into the system, where the data represents one or more elements of work performed at one or more locations. This data is parsed out into individual items to be audited. These items, along with a number of questions with discrete answers are then transmitted by the system to one or more auditing technicians who audit the work performed by capturing one or more visual images. These visual images, along with answers to the questions are then transmitted back to the system. The system then saves the visual images and associated answers for archiving and generating reports. | 11-15-2012 |
Patent application number | Description | Published |
20100028984 | DEVICES AND METHODS FOR BIOCHIP MULTIPLEXING - The invention is directed to a method of analyzing a plurality of biochips. In particular, the method includes inserting a first biochip in to a first station of an analysis device, inserting a second biochip into a second station of the analysis device, wherein each of the first and second biochips comprise a substrate that includes an array of detection electrodes, each including a different capture binding ligand, a different target analyte, and a label, and a plurality of electrical contacts, detecting current as an indication of the presence of the labels on the first biochip and detecting current as an indication of the presence of the labels on the second biochip. | 02-04-2010 |
20120252008 | COMPOSITIONS AND METHODS FOR CAPTURE AND ELUTION OF BIOLOGICAL MATERIALS VIA PARTICULATES - Lysing may include agitating a specimen in a chamber along with a medium that includes a particulate lysing material that has an affinity for a biological material. Lysing material may include beads or other material which may be coated that facilitates binding. The medium may include a fluid with a high salt or low pH level. Binding of biological materials to solid surfaces may be induced by particular media. The biological material may be eluted by lowering a concentration of salt or increasing a pH level. Lysing materials with two or more different affinities may be employed. Lysing materials may include particles of different sizes. Heating may be used. Lysing may be performed in a flow through apparatus. Surfaces of solid materials may be modified to capture bacteria with high cell wall lipid content. | 10-04-2012 |
20140127773 | COMPOSITIONS AND METHODS FOR CAPTURE AND ELUTION OF BIOLOGICAL MATERIALS VIA PARTICULATES - Lysing may include agitating a specimen in a chamber along with a medium that includes a particulate lysing material that has an affinity for a biological material. Lysing material may include beads or other material which may be coated that facilitates binding. The medium may include a fluid with a high salt or low pH level. Binding of biological materials to solid surfaces may be induced by particular media. The biological material may be eluted by lowering a concentration of salt or increasing a pH level. Lysing materials with two or more different affinities may be employed. Lysing materials may include particles of different sizes. Heating may be used. Lysing may be performed in a flow through apparatus. Surfaces of solid materials may be modified to capture bacteria with high cell wall lipid content. | 05-08-2014 |
Patent application number | Description | Published |
20080267215 | System and method of identifying a location associated with a source of a data communication problem - In a particular illustrative embodiment, a method is disclosed that includes receiving data at a central server system from multiple customer premises equipment (CPE) devices. The CPE devices are located at subscriber premises remote from one another. The method further includes associating the received data from geographically-related CPE devices and comparing the associated data to determine a problem related to one or more of the geographically-related CPE devices. | 10-30-2008 |
20100318647 | System and Method to Determine Network Usage - Systems and methods to measure network usage are provided. A particular method includes collecting first usage data from a first network device of a network at a network usage tracking system. The first network device determines the first usage data based on an inband measurement of data passing through the first network device. The method includes collecting second usage data from a second network device of the network at the network usage tracking system. The first network device and the second network device are different network devices. The method includes matching the first usage data and the second usage data to user accounts. The network usage data is determined based on the first usage data, the second usage data, and the user accounts. | 12-16-2010 |
20120151078 | METHOD AND APPARATUS FOR CAPACITY DIMENSIONING IN A COMMUNICATION NETWORK - A method, computer readable medium and apparatus for calculating a capacity for high speed packet access data in a link in a communications network are disclosed. For example, the method initializes parameters associated with streaming data, long elastic data and short elastic data, determines, via a processor, a capacity value such that a quality of service metric is met for the streaming data, the long elastic data and the short elastic data and provisions the link with the capacity value if the quality of service metric is met. | 06-14-2012 |
20120239805 | System and Method to Determine Network Usage - A method includes determining a first upload usage value and a first download usage value for a user account for a time interval from cell counter data retrieved from a first network device. The method includes determining a second download usage value for the user account for the time interval based on session information from a second network device. The method includes adding an upload usage value based on the first upload usage value and the second upload usage value to a cumulative upload usage value for the user account and adding a download usage value based on the first download usage value and the second download usage value to a cumulative download usage value for the user account. The method also includes sending the cumulative upload usage value and the cumulative download usage value to a billing system. | 09-20-2012 |
20140082203 | METHOD AND APPARATUS FOR CAPACITY DIMENSIONING IN A COMMUNICATION NETWORK - A method, computer readable medium and apparatus for calculating a capacity for high speed packet access data in a link in a communications network are disclosed. For example, the method initializes parameters associated with streaming data, long elastic data and short elastic data, determines, via a processor, a capacity value such that a quality of service metric is met for the streaming data, the long elastic data and the short elastic data and provisions the link with the capacity value if the quality of service metric is met. | 03-20-2014 |
Patent application number | Description | Published |
20080292064 | METHODS AND APPARATUS TO CHARACTERIZE A DIGITAL SUBSCRIBER LINE (DSL) SUBSCRIBER LOOP - Methods and apparatus to characterize a digital subscriber line (DSL) subscriber loop are disclosed. An example method comprises selecting a portion of a search space based on a measured transfer function response, the search space defining a plurality of combinations of transmission line parameters, and identifying a characterizing parameter of a digital subscriber line (DSL) subscriber loop from the selected portion of the search space, the characterizing parameter having an associated transfer function that substantially corresponds with the measured transfer function response. | 11-27-2008 |
20090245336 | METHODS AND APPARATUS TO DETERMINE DIGITAL SUBSCRIBER LINE CONFIGURATION PARAMETERS - Example methods and apparatus to determine digital subscriber line (DSL) configuration parameters based on current and historical DSL performance characteristics are disclosed. A disclosed method includes obtaining first data representative of a current performance characteristic for a DSL modem, obtaining second data representative of a historical performance characteristic for the DSL modem, computing, at a maintenance server, a configuration parameter using the first and the second data, and reinitializing the DSL modem with the computed DSL configuration parameter when the computed configuration parameter has a value different from a previous value of the configuration parameter, wherein the DSL configuration parameter is computed prior to the reinitializing of the DSL modem. | 10-01-2009 |
20110129071 | METHODS, APPARATUS AND ARTICLES OF MANUFACTURE TO CHARACTERIZE CUSTOMER-PREMISES NETWORKS - Methods, apparatus and articles of manufacture to characterize customer-premises networks are disclosed. A disclosed example method comprises retrieving a first plurality of performance parameters for a first time interval for respective ones of a plurality of customer-premises devices, the first plurality of customer-premises devices forming a first customer-premises communication network and each communicatively coupled to a first residential gateway, retrieving a second plurality of performance parameters for a second time interval for the respective ones of the first plurality of devices, computing a first metric representative of a performance variability of the first customer-premises communication network from the first and second plurality of performance parameters, and comparing the first metric to a second metric representative of a second performance variability of a second customer-premises communication network communicatively coupled to a second residential gateway to determine whether the first customer-premises communication network is operating in accordance with a normal operating condition. | 06-02-2011 |
20120284737 | System and Method for a Video Content Service Monitoring and Provisioning Architecture - According to one example embodiment a storage medium having computer instructions which, responsive to being executed by at least one processor, cause the at least one processor to perform operations. The operations can include analyzing data from data sources of an internet-protocol television network where the data provided by the data sources includes set-top-box data having voice over internet protocol usage for a plurality of subscribers of the internet protocol television network in a geographic area and correlating video provisioning information obtained from the data sources, individual subscriber channel viewing information, internet-usage data, subscriber data and demographic data to produce correlated information. The operations can include generating one or more reports associated with the plurality of subscribers in the geographic area based on the correlated information. Other embodiments are disclosed. | 11-08-2012 |