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Bissell, US
Douglas Eric Bissell, Monroe, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110243758 | LIQUID RING PUMP WITH GAS SCAVENGE DEVICE - A liquid ring pump having a channel including a first opening which opens into a first bucket formed by rotor blades. The first opening is located along an arcuate path between a closing edge of an inlet port and a leading edge of a discharge port The inlet port and discharge port are in a port plate of the liquid ring pump. The channel has a second opening which opens into a second bucket formed by rotor blades The second opening is on an arcuate path between a closing edge of the discharge port and a leading edge of the inlet port. A fluid pathway interconnects the first and second openings. At least a portion of the liquid ring pump forming the channel is disposed in a circumferential cylindrical cavity, wherein the cavity is formed from a plurality of axially extending rotor blade ends. | 10-06-2011 |
| 20110286840 | LIQUID RING PUMP WITH LINER - A liquid ring pump is provided that includes an annular housing having an inner surface forming a housing cavity. The annular housing is filled with an operating fluid during operation of the pump. The operating fluid forms an eccentric liquid ring in the annular housing during operation of the pump. A rotor is disposed in the housing cavity and includes a plurality of rotor blades. A shaft extends into the annular housing into the housing cavity. The plurality of rotor blades extend radially outward from the shaft toward the inner surface of the annular housing. A liner formed from a corrosion resistant material is disposed substantially flush with at least a portion of the annular housing inner surface opposite a plurality of rotor blade ends. | 11-24-2011 |
Douglas Eric Bissell, Monros, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20120076671 | METHOD OF CONVERTING LIQUID RING PUMPS HAVING SEALING LIQUID VENTS - Converting a liquid ring pump which vents sealing liquid (compressant) from the working chamber of the pump to a liquid ring pump having a gas venting system by retasking a selected passage of the liquid ring pump. The passage is selected from a group of passages consisting of ( | 03-29-2012 |
Henry Martyn Bissell, Oak View, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100167608 | Freediving Safety Apparatus - An apparatus for use in the activity of freediving, providing the freediver with increased safety and protection in the event of Shallow Water Blackout, incapacitating hypoxia, or other emergency occurring in or under the water, while providing greater reliability of functioning, and comfort of wearing during the activity of freediving. | 07-01-2010 |
Michael G. Bissell, Reynoldsburg, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20080206787 | Process to determine enzyme activity - The present invention provides for various processes for determining enzyme activity. In one embodiment, a process for detecting an enzyme activity includes contacting a blood component with a substrate comprising a cleavage site of the enzyme and a tag moiety to produce a sample comprising a cleavage product having a known mass, and placing the sample in contact with a SELDI sample chip which has surface moieties which bind to the cleavage product. In another embodiment, the process further includes subjecting the SELDI sample chip to SELDI mass spectrometry to identify the cleavage product. The present invention also provides for a kit which includes a SELDI sample chip having surface moieties capable of binding to an enzyme cleavage product. | 08-28-2008 |
Mina J. Bissell, Berkeley, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090191543 | IDENTIFICATION OF RAC1B AS A MARKER AND MEDIATOR OF METALLOPROTEINASE-INDUCED MALIGNANCY - The present invention provides compositions and methods for detecting MMP-induced malignancies by detecting Rac1b expression. The invention further provides compositions and in vitro and in vivo methods for inhibiting MMP-induced malignant transformation by modulating Rac1b expression and/or function. | 07-30-2009 |
| 20090274626 | TARGETING TNF-alpha CONVERTING ENZYME(TACE)- DEPENDENT GROWTH FACTOR SHEDDING IN CANCER THERAPY - The invention provides methods for modulating tumor cell proliferation by contacting cells (e.g. tumor cells) with a TACE inhibitor and a compound that inhibits EGFR tyrosine kinase, whereby the TACE inhibitor enhances the sensitivity of the cell to the EGFR tyrosine kinase inhibitor. Additionally, methods for treating cancer and methods for identifying TACE inhibitors is also provided. | 11-05-2009 |
| 20100034828 | Method of Increasing Radiation Sensitivity by Inhibition of Beta One Integrin - A method for increasing or monitoring apoptosis in tumor cells by the co-administration of ionizing radiation and an anti-integrin antibody. Increasing apoptosis reduces tumor growth in vivo and in a cell culture model. The antibody is directed against the beta-1 integrin subunit and is inhibitory of beta-1 integrin signaling. Other molecules having an inhibitory effect on beta-1 integrin, either in signaling or in binding to its cognate extracellular receptors may also be used. The present method is particularly of interest in treatment of tumor cells associated with breast cancer, wherein radiation is currently used alone. The present method further contemplates a monoclonal antibody suitable for human administration that may further comprise a radioisotope attached thereto. | 02-11-2010 |
| 20100062000 | Rhamm, a Co-Receptor and Its Interactions with Other Receptors in Cancer Cell Motility and the Identification of Cancer Prognitor Cell Populations - CD44 is an integral hyaluronan receptor that can either promote or inhibit motogenic signaling in tumor cells. Rhamm is a non-integral cell surface (CD168) and intracellular hyaluronan binding protein that promotes cell motility in vitro and whose expression is strongly upregulated in aggressive tumors. The present invention describes compositions and methods for the prognosis and diagnosis of cancer by the detection of CD44/Rhamm complexes. The use of labeled Rhamm-binding agents in culture and in vivo to identify tumorigenic progenitor cells that exhibit an aggressive phenotype characterized by high Rhamm and CD44 expression is further described. Specific methods include using hyaluronan to target imaging or therapeutic agents to these progenitor tumor subsets in breast and likely other cancers. | 03-11-2010 |
| 20100143382 | MODULATION OF RHAMM (CD168) FOR SELECTIVE ADIPOSE TISSUE DEVELOPMENT - Herein is described the methods and compositions for modulation of Rhamm, also known as CD 186, and its effects on wound repair, muscle differentiation, bone density and adipogeneisis through its ability to regulate mesenchymal stem cell differentiation. Compositions and methods are provided for blocking Rhamm function for selectively increasing subcutaneous, but not, visceral fat. Compositions and methods for modulating Rhamm in wound repair are also described. | 06-10-2010 |
Pamela Bissell, Ewing, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20120059278 | Compound Curette with Layered Anti-Pathogen Protection and Liquid Delivery System - A compound curette for removing tissue samples and delivering liquid and anti-pathogen to the treated area includes a hollow handle that fits a reservoir with a medicated or cosmeceutical solution. A solution is delivered from the reservoir through a channel to a scraping end of the curette by a button activated mechanism. The scraping end of the curette is made of a metal or hard plastic and is covered in anti-pathogen material. The liquid delivery allows placing a medicine or sterilizing solution directly at the locust of the infection. Pathogen inhibition coating provides for a good safeguard to stop or slow bacteria or fungus proliferation. The method of scraping debris and medication delivery is particularly useful for the treatment of onychomycosis, commonly referred to as a fungus infection of the toenail. Main portions of the curette could be detachable, allowing for the easy reservoir replacement and for the use of multiple scraping utensils. Similarly, the device could be manufactured for a single use when all parts are molded together. | 03-08-2012 |
Richard L. Bissell, Rio Rancho, NM US
| Patent application number | Description | Published |
|---|---|---|
| 20100269681 | Pointing Device Inertial Isolation and Alignment Mounting System - An inertial isolation and alignment system for a sensitive component or apparatus affixed to a mortar barrel comprising a barrel clamp assembly which supports two parallel bearing rail followers and pointing device cage assembly which supports two parallel linear bearing rails. The bearing rail followers and linear bearing rails form a simple sliding contact linear motion bearing system. The bearing rail followers on the barrel clamp assembly allow the cage assembly to slide freely along the length of the linear bearing rails. During firing, the travel vector is decoupled from the cage assembly by the bearing rail followers as they move with the barrel along the linear bearing rails leaving the cage assembly suspended in inertial space. The cage assembly then accelerates under the force of gravity over the distance of the displaced travel of the bearing rail followers back to its rest position landing on dampers, each on a linear bearing rail. | 10-28-2010 |
Steven R. Bissell, Andover, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090094832 | Heat treating apparatus and method of using same - An apparatus and method for heat treating the welded area of a repaired gas turbine engine component uses first and second heating elements. The heating elements each include an insulating tube supported by a support rod and wrapped with a conducing wire. One of the heating elements is sized to fit inside a recess in the gas turbine engine component, adjacent to the welded area, while the second heating element is placed outside the recess, but also adjacent to the welded area, thereby heating the welded area from two sides. | 04-16-2009 |