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Birkle

James Birkle, Redwood City, CA US

Patent application numberDescriptionPublished
20100050571Method And Apparatus For Inflating And Sealing Packing Cushions With Rotary Sealing Mechanism - An apparatus for inflating and sealing packing cushions has a drive mechanism for feeding a preconfigured film material to a sealing mechanism in a flattened state without wrinkles in the sealing region in which a longitudinal seal is formed. In one aspect, the drive mechanism comprises a pair of upper adjacent belts and a backing element, such as a lower belt. The sealing mechanism may be a rotary sealing wheel that contacts the film material between the upper adjacent belts.03-04-2010

Jochen Birkle, Tettnang DE

Patent application numberDescriptionPublished
20090298647HYDRAULIC CIRCUIT ARRANGEMENT FOR OPERATING A HYDRODYNAMIC TORQUE CONVERTER - A hydraulic circuit arrangement for operating a hydrodynamic torque converter (12-03-2009

Siegfried Birkle, Höchstadt DE

Patent application numberDescriptionPublished
20090130658Arrangement for integrated and automated dna or protein analysis in a single-use cartridge, method for producing such a cartridge and operating method for dna or protein analysis using such a cartridge - A cartridge (card) having a system of microchannels and/or microcavities is used for automated DNA or protein analysis. In at least one embodiment, the microchannels or microcavities include geometrical structures for receiving dry reagents. For the purpose of industrial production, the cartridge is produced from a flat card support, e.g., by injection moulding. The reagents are spotted into the open channels, dried and then the channels are sealed by way of a film. A finished cartridge can thus be provided with a test sample and the fully automated measuring sequence can be initiated by inserting said cartridge into a read-out device.05-21-2009
20090136922Method for carrying out an electrochemical measurement on a liquid measuring sample in a measuring chamber that can be accessed by lines, and corresponding arrangement - Especially in order to carry out the so-called enzyme-coupled DNA hybridisation test in a closed cartridge including a microfluid system, using stored dry reagents, the reagents must be dissolved in the microfluid system and transported into the measuring chamber directly before the measurement. During the dissolution of the reagents in water, air cushions that cannot reach the measuring chamber must absolutely be prevented from forming upstream of the reagent liquid. According to an embodiment of the invention, the liquid measuring sample and the liquid reagents are transported in such a way that the air cushion is directed into the waste line and the measuring sample and the reagents are then introduced into the measuring chamber without any air bubbles. In this way, measuring errors can be avoided.05-28-2009
20090168300High-voltage capacitor - A high-voltage capacitor is used to transmit energy and has an insulator housing, wherein at least two serially connected capacitors, which are mounted in parallel, are arranged. Said capacitors are made of, respectively, a serial connection of individual capacitors which are embodied as stackable capacitor elements. The resulting high-voltage capacitor is compact and economical. Each capacitor element comprises several individual capacitors which are maintained in an isolated manner, whereby the number corresponds to the number of serially connected capacitors, such that said serially connected capacitors are formed by one stack of capacitor elements.07-02-2009

Patent applications by Siegfried Birkle, Höchstadt DE

Siegfried Birkle, Höchstadt DE

Patent application numberDescriptionPublished
20090168300High-voltage capacitor - A high-voltage capacitor is used to transmit energy and has an insulator housing, wherein at least two serially connected capacitors, which are mounted in parallel, are arranged. Said capacitors are made of, respectively, a serial connection of individual capacitors which are embodied as stackable capacitor elements. The resulting high-voltage capacitor is compact and economical. Each capacitor element comprises several individual capacitors which are maintained in an isolated manner, whereby the number corresponds to the number of serially connected capacitors, such that said serially connected capacitors are formed by one stack of capacitor elements.07-02-2009

Stéphane Birkle, Nantes FR

Patent application numberDescriptionPublished
20100150910USE OF MONOCLONAL ANTIBODIES SPECIFIC TO THE O-ACETYLATED FORM OF GD2 GANGLIOSIDE FOR TREATMENT OF CERTAIN CANCERS - The invention relates to the use of monoclonal antibodies that only recognise the O-acetylated form of the GD2 ganglioside, or fragments of said antibody, for the diagnosis and the treatment of cancers in which the cells express the O-acetylated GD2, said antibody or said fragment recognising the O-acetylated GD2 molecules expressed by the tumoral cells and not recognising the GD2 molecules expressed at the surface of the peripheral nerves, in order to increase the specificity of the diagnosis and reduce the toxicity of the treatments. The invention also relates to artificially modified antibodies advantageously used for treating and diagnosing cancers in which the cells express the O-acetylated GD2.06-17-2010

Stéphane Birkle, Nantes FR

Patent application numberDescriptionPublished
20100150910USE OF MONOCLONAL ANTIBODIES SPECIFIC TO THE O-ACETYLATED FORM OF GD2 GANGLIOSIDE FOR TREATMENT OF CERTAIN CANCERS - The invention relates to the use of monoclonal antibodies that only recognise the O-acetylated form of the GD2 ganglioside, or fragments of said antibody, for the diagnosis and the treatment of cancers in which the cells express the O-acetylated GD2, said antibody or said fragment recognising the O-acetylated GD2 molecules expressed by the tumoral cells and not recognising the GD2 molecules expressed at the surface of the peripheral nerves, in order to increase the specificity of the diagnosis and reduce the toxicity of the treatments. The invention also relates to artificially modified antibodies advantageously used for treating and diagnosing cancers in which the cells express the O-acetylated GD2.06-17-2010

Thomas Birkle, Boulder, CO US

Patent application numberDescriptionPublished
20100002889SYSTEM AND METHOD FOR DESIGNING SOUND SYSTEMS - The invention is directed to a display and method for conducting sound system design. The display is configured to simultaneously show a sound system model comprising both audio components and sound environment components, a plurality of parameters and a graphic representation of a calculated sound system performance attribute. In response to receiving input from the user and without any additional user intervention, the display re-displays a newly-calculated sound system performance attribute such as, for example, a graphic representation in the sound system model of a sound path associated with a user-selected reflected sound identifier. A processor also simulates, based on the sound system configuration, the sound performance that a user would expect to hear positioned in an identified listening position of the sound system model.01-07-2010