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Binkowski
Brent A. Binkowski, Minneapolis, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20090240104 | Surgical Articles and Methods for Treating Pelvic Conditions - An implant, insertion tool, combinations, and associated methods, that involve placement of a self-fixating tip at tissue of the pelvic region, wherein an insertion tool includes one or more of an aperture for engaging a guide and an extension guard, the method optionally allowing for initial placement of a self-fixating tip at tissue of the pelvic region and adjustment of the location of the self-fixating tip. A threading guide is provided to assist in threading the guide through the aperture. An anchor also provided to with a retaining member to retain the anchor in tissue. | 09-24-2009 |
Brock Binkowski, Sauk City, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20090305280 | Luciferase biosensors for camp - A modified luciferase protein which is a sensor for molecules including cAMP is provided. The modified luciferase protein includes one or more heterologous amino acid sequences, at least one of which directly or indirectly interacts with cAMP. | 12-10-2009 |
| 20110039257 | Permuted and nonpermuted luciferase biosensors - A modified luciferase protein which is a sensor for molecules including cAMP, cGMP, calcium, chelators thereof, kinases, or phosphatases is provided. Also provided is a circularly permuted anthozoan luciferase protein and a decapod crustacean luciferase protein, optionally containing one or more heterologous amino acid sequences, at least one of which directly or indirectly interacts with a molecule of interest. Further provided is a modified anthozoan luciferase protein and a decapod crustacean luciferase protein containing an insertion of one or more heterologous amino acid sequences, at least one of which directly or indirectly interacts with a molecule of interest. | 02-17-2011 |
| 20110283373 | MUTANT PROTEASE BIOSENSORS WITH ENHANCED DETECTION CHARACTERISTICS - A polynucleotide encoding a biosensor polypeptide comprising a modified circularly-permuted thermostable luciferase and a linker linking the C-terminal portion of the thermostable luciferase to the N-terminal portion of the thermostable luciferase. The modified circularly-permuted thermostable luciferase is modified relative to a parental circularly-permuted thermostable luciferase. The linker contains a sensor region capable of interacting with a target molecule in a cell. The modified circularly-permuted thermostable luciferase has an enhanced response after interaction of the biosensor with the target molecule relative to the parental circularly-permuted thermostable luciferase in the presence of the target molecule. Alternatively, the modified circularly-permuted thermostable luciferase has an enhanced response after interaction of the biosensor with the target molecule relative to the modified circularly-permuted thermostable luciferase in the absence of the target molecule. | 11-17-2011 |
Dirk Binkowski, Mannheim DE
| Patent application number | Description | Published |
|---|---|---|
| 20110309558 | METHOD FOR PRODUCING MOLDED PARTS FROM A POLYOXYMETHYLENE POLYMER - The invention relates to a process for the production of moldings composed of a polyoxymethylene polymer via blow molding, in which the polyoxymethylene polymer is extruded to give tubing, using an extruder with a grooved feed section, where the feed section is heated to a temperature in the range from 100 to 230° C., and the extruded tubing composed of the polyoxymethylene polymer is introduced into a blow mold, and a molding composed of the extruded tubing is produced in the blow mold. | 12-22-2011 |
Norbert Binkowski, Franklin, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110010929 | SYSTEMS FOR PRODUCING ASSEMBLIES - This invention relates to methods and systems for attaching components to strips of material to form assemblies, e.g., a system for fastening pre-sharpened razor blades to individual support strips on a continuous band of material, such as a metal, to form discrete blade assemblies. | 01-20-2011 |