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Binder, AT

Bernd Binder, Wien AT

Patent application numberDescriptionPublished
20080313751Method by Using Human or Mice-Isg12 to Develop and Prepare Drugs and Single Nucleotide Polymorphism in the Isg12 Gene for Diagnostic Use - Here is described a novel gene, the interferon inducible gene 12 (ISG12, IFI27), that interacts with nuclear receptors and enhances nuclear export of such transcription factors. As a consequence, the transcriptional activities of these nuclear receptors are decreased. As examples effects on NR4A1 and PPARa and PPARg are given. When ISG12 is absent as in ISG12 deficient mice transcriptional activities of these nuclear receptors are not impaired and their protective effects are fully appreciated. Consistently, ISG12 deficient mice are resistant to restenosis upon carotid artery ligation and to endotoxin induced death. Human genetics studies indicate the importance of ISG12 where the inventors could show a strong association between an intronic ISG12 SNP and the presence of hypercholesterolemia, diabetes type 2 and stroke. ISG12 is therefore a target for novel therapeutic strategies for the treatment of vascular diseases.12-18-2008
20100216174METHOD OF EVALUATING THROMBOGENIC MICROPARTICLES - A method and a kit are disclosed for evaluating thrombogenic microparticles (MP). The principle is based on the evaluation of thrombin generation in platelet poor plasma (PPP) and in plasma made microparticle free (MPFP) by centrifugation or filtration. The difference in thrombin generation between PPP and MPFP correlates with number and activity of thrombogenic microparticles. Evaluating thrombin generation of different standardized amounts of MPs in standard MPFP allows to calculate the number of thrombogenic MP from the difference in thrombin generation between PPP and MPFP.08-26-2010

Bernd Binder, Vienna AT

Patent application numberDescriptionPublished
20100203562PLASMA FILTRATION - The invention relates to a process for preparing blood plasma for determining one or more blood parameters, in particular coagulation parameters. In order to improve the measurement, the blood plasma is sucked through a filter by means of reduced pressure.08-12-2010

Dieter Binder, Wien AT

Patent application numberDescriptionPublished
20090239852USE OF OXICAM COMPOUNDS - Methods of treating and/or preventing arteriosclerosis are disclosed. In certain methods, a composition containing at least one lornoxicam or lornoxicam analogue that inhibits cyclooxygenase 1 and cyclooxygenase 2 (COX 1 and COX 2), cannot cross the blood/brain barrier under physiological conditions, and reduces the prostaglandin E2-induced induction of the amyloid precursor protein (APP) is administered to a subject to treat and/or prevent arteriosclerosis in the subject.09-24-2009
20100076011Enantiomer-Pure Hexahydro-Pyrrolocyclopenta-Pyridine Derivatives - The invention relates to the novel therapeutically valuable enantiomer-pure [3aα,8bα]-1,2,3a,4,8b-hexahydropyrrolocyclopentapyridine derivatives of the general formula (I), wherein Z is a single bond or CH03-25-2010

Patent applications by Dieter Binder, Wien AT

Elisabeth Binder, Wien AT

Patent application numberDescriptionPublished
20080313751Method by Using Human or Mice-Isg12 to Develop and Prepare Drugs and Single Nucleotide Polymorphism in the Isg12 Gene for Diagnostic Use - Here is described a novel gene, the interferon inducible gene 12 (ISG12, IFI27), that interacts with nuclear receptors and enhances nuclear export of such transcription factors. As a consequence, the transcriptional activities of these nuclear receptors are decreased. As examples effects on NR4A1 and PPARa and PPARg are given. When ISG12 is absent as in ISG12 deficient mice transcriptional activities of these nuclear receptors are not impaired and their protective effects are fully appreciated. Consistently, ISG12 deficient mice are resistant to restenosis upon carotid artery ligation and to endotoxin induced death. Human genetics studies indicate the importance of ISG12 where the inventors could show a strong association between an intronic ISG12 SNP and the presence of hypercholesterolemia, diabetes type 2 and stroke. ISG12 is therefore a target for novel therapeutic strategies for the treatment of vascular diseases.12-18-2008

Eva Binder, Unterwart AT

Patent application numberDescriptionPublished
20090068706Production of Highly Isotopically Labelled, Secondary, Microbial Metabolic Products, and Corresponding Metabolic Products - The invention relates to a method for producing isotopically labelled secondary metabolic products of fungi or bacteria in a liquid synthetic culture medium. According to said method, the synthesis is carried out by immobilizing the fungi or bacteria on an inert carrier, adding a liquid synthetic culture medium in which essentially all of the carbon atoms, nitrogen atoms and/or sulphur atoms are replaced by stable isotopes.03-12-2009

Eva Binder, Wien AT

Patent application numberDescriptionPublished
20090239852USE OF OXICAM COMPOUNDS - Methods of treating and/or preventing arteriosclerosis are disclosed. In certain methods, a composition containing at least one lornoxicam or lornoxicam analogue that inhibits cyclooxygenase 1 and cyclooxygenase 2 (COX 1 and COX 2), cannot cross the blood/brain barrier under physiological conditions, and reduces the prostaglandin E2-induced induction of the amyloid precursor protein (APP) is administered to a subject to treat and/or prevent arteriosclerosis in the subject.09-24-2009
20100076011Enantiomer-Pure Hexahydro-Pyrrolocyclopenta-Pyridine Derivatives - The invention relates to the novel therapeutically valuable enantiomer-pure [3aα,8bα]-1,2,3a,4,8b-hexahydropyrrolocyclopentapyridine derivatives of the general formula (I), wherein Z is a single bond or CH03-25-2010

Patent applications by Eva Binder, Wien AT

Eva Maria Binder, Unterwart AT

Patent application numberDescriptionPublished
20100196323Probiotic health or fitness promoting human or animal foodstuff and/or drinking water additive and use thereof - The invention relates to a probiotic health or fitness promoting human or animal foodstuff and/or drinking water additive, comprising a mixture of microorganisms, selected from the group 08-05-2010
20100258494Packing Material for a Micro-Adsorption Column for Drying and/or Purification of Dissolved Organic or Biological Analytes and Micro-Adsorption Column and use thereof - The invention relates to a packing material for a micro-adsorption column for drying and/or purification of dissolved organic or biological analytes, such as toxins, antibiotics, vitamins, hormones, pesticides and similar, containing at least one drying agent which contains magnesium sulphate and at least one further drying agent selected from the group comprising aluminium oxide, calcium chloride, calcium hydride, calcium oxide, calcium sulphate, potassium hydride, silica gel, copper sulphate, magnesium oxide, magnesium perchlorate, molecular sieves, sodium hydroxide, phosphorus pentoxide, sulphuric acid on silica, phosphorus pentoxide on silica and 0.5 to 90 wt. % of a naturally-occurring or synthetic support with large internal surface such as zeolite, diatomic earths, bentonite, silicon dioxide or similar. The invention further relates to a micro-adsorption column packed with the above and use thereof.10-14-2010

Eva-Maria Binder, Tulln AT

Patent application numberDescriptionPublished
20090098244Microorganism for biological detoxification of mycotoxins, namely ochratoxins and/or zearalenons, as well as method and use thereof - A microorganism for the biological inactivation or detoxification of mycotoxins, in particular ochratoxins, which is selected from bacteria and/or yeasts, which cleaves the phenylalanine group of the mycotoxins, in particular ochratoxins, as well as a method for biologically inactivating or detoxifying mycotoxins, in particular ochratoxins, in food products and animal feeds by the aid of a microorganism, and the use of the microorganism(s).04-16-2009
20110142991Method for treating feed silage for ruminants and feed silage additive - In a method for treating feed silage for ruminants, by which silage is mixed with a microorganism and the mixture of feed silage and microorganism is stored in a closed container for at least 30 days, it is provided that the feed silage is mixed with at least two microorganisms selected from the group consisting of 06-16-2011

Patent applications by Eva-Maria Binder, Tulln AT

Georg Binder, Pettenbach AT

Patent application numberDescriptionPublished
20090199882Method and device for cleaning welding torches - A device for cleaning welding torches includes a device for applying cleaning or wetting liquid to the tip of the welding torch and a coil with an opening for inserting the welding torch in order to subject it to an electromagnetic cleaning. The device also includes an electric power supply device that is connected to the coil. The device for applying cleaning liquid, which consists of, for example, a reservoir or nozzles, and the coil are placed inside a common housing together with a refuse reservoir, which is located underneath the coil while serving to hold the electromagnetically removed foreign substances. Preferably, the device for applying cleaning liquid is placed inside or underneath the opening of the coil thereby enabling the welding torch to be located in essentially the same position during cleaning.08-13-2009

Patent applications by Georg Binder, Pettenbach AT

Josef Binder, Krems AT

Patent application numberDescriptionPublished
20110171460Laminate and Method for the Production Thereof - The invention relates to a laminate, the top layer thereof comprising a paper impregnated with an aminoplast resin and surface modified silica nanoparticles. According to the invention the surface modified silica nanoparticles comprise at least one silane on the surfaces thereof, said silane carrying at least one functional group. The invention further relates to a method for the production of a laminate of said type.07-14-2011

Oliver Binder, Wels AT

Patent application numberDescriptionPublished
20100187795SKI - The invention relates to a ski having a ski blade, the ski being configured in layers, the ski blade having at least one material recess, and the ski comprising at least one strap made of a high-strength opaque material, particularly metal, such as aluminum, and at least one strap made of a rigid translucent material, characterized in that the material recess (07-29-2010

Thomas Binder, Feldkirch AT