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Bigwood
Bob Bigwood, Hillsboro, OR US
| Patent application number | Description | Published |
|---|---|---|
| 20100025858 | WINGED VIAS TO INCREASE OVERLAY MARGIN - Winged via structures to increase overlay margin are generally described. In one example, a method comprises depositing a sacrificial layer to an interlayer dielectric, the interlayer dielectric being coupled with a semiconductor substrate, forming at least one trench structure in the sacrificial layer wherein the trench structure comprises a first direction along a length of the trench structure and a second direction along a width of the trench structure wherein the second direction is substantially perpendicular to the first direction, depositing a light sensitive material to the trench structure and the sacrificial layer, and patterning at least one winged via structure in the light sensitive material to overlay the trench structure wherein the winged via structure extends in the second direction beyond the width of the trench structure onto the sacrificial layer. | 02-04-2010 |
Douglas Bigwood, Madison, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080311601 | Methods for Prediction and Prognosis of Cancer, and Monitoring Cancer Therapy - The present invention relates to biomarkers and the use of biomarkers for the prediction and prognosis of cancer as well as the use of biomarkers to monitor the efficacy of cancer treatment. Specifically, this invention relates to the use of VEGF as a biomarker for multi-kinase inhibitors. | 12-18-2008 |
| 20080311604 | Methods for Prediction and Prognosis of Cancer, and Monitoring Cancer Therapy - The present invention relates to biomarkers and the use of biomarkers for the prediction and prognosis of cancer as well as the use of biomarkers to monitor the efficacy of cancer treatment. Specifically, this invention relates to the use of soluble VEGF-R2 as a biomarker for multi-kinase inhibitors. | 12-18-2008 |
| 20100233680 | Gene Expression Profiles and Methods of Use - The present invention relates to gene expression profiles, microarrays comprising nucleic acid sequences representing gene expression profiles, and methods of using expression profiles and microarrays. The invention also provides methods and compositions for diagnostic assays for detecting cancer and therapeutic methods and compositions for treating cancer. The invention also provides methods for designing, identifying, and optimizing therapeutics for cancer. | 09-16-2010 |
Douglas Bigwood, Medison, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100209914 | METHODS, SYSTEMS, AND KITS FOR EVALUATING MULTIPLE SCLEROSIS - The present invention provides a method for evaluating multiple sclerosis (MS), or excluding MS as a diagnosis for a patient The method comprises determining a gene expression profile for a sample from such a patient. The gene expression profile, which contains gene expression values for a plurality of genes that are differentially expressed in white blood cells of MS patients, is compared to an MS-profile and/or a non-MS profile, and classified. The invention also provides a method for monitoring treatment of an MS patient Pre-treatment and post-treatment gene expression profiles contain gene expression values for a plurality of genes that are differentially expressed upon treatment of MS patients. The expression profiles may then be compared, to identify differences between pre-treatment and post-treatment gene expression. These differences are indicative of the patient's response to treatment The invention further provides kits and systems for performing the methods of the invention. | 08-19-2010 |
Douglas W. Bigwood, Madison, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20120015830 | MICRORNA PROFILES FOR EVALUATING MULTIPLE SCLEROSIS - The present invention provides methods, systems, and kits for evaluating multiple sclerosis (MS) in a patient. Particularly, the invention provides convenient miRNA-based tests for evaluating a patient for MS, including for diagnosing MS, for excluding MS as a diagnosis, for determining the presence of disease activity associated with MS, and for monitoring the course of disease or efficacy of treatment for MS. | 01-19-2012 |
Michael C. Bigwood, Oreland, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110224323 | POLYESTERS, METHODS OF THEIR PREPARATION AND USE - Crosslinked polycondensation products of: (a) polyols selected from the group consisting of: (1) polyols with three or more hydroxyl groups, (2) acetal forms of (1), and (3) mixtures thereof, and (b) polyacids selected from the group consisting of: (1) polyacids with two or more carboxylic groups, (2) anhydrides of (1), (3) esters of (1), and (4) mixtures thereof are disclosed. The resulting polyesters have a molar ratio of polyol to polyacid from about 1:3 to about 3:1 and are highly-crosslinked. Preferred monomers are sustainable monomers such as glycerol, citric acid, fumaric acid, and sebacic acid. Two-step heating processes for preparing the high molecular weight polyesters are also provided. | 09-15-2011 |
Michael P. Bigwood, Oreland, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110224323 | POLYESTERS, METHODS OF THEIR PREPARATION AND USE - Crosslinked polycondensation products of: (a) polyols selected from the group consisting of: (1) polyols with three or more hydroxyl groups, (2) acetal forms of (1), and (3) mixtures thereof, and (b) polyacids selected from the group consisting of: (1) polyacids with two or more carboxylic groups, (2) anhydrides of (1), (3) esters of (1), and (4) mixtures thereof are disclosed. The resulting polyesters have a molar ratio of polyol to polyacid from about 1:3 to about 3:1 and are highly-crosslinked. Preferred monomers are sustainable monomers such as glycerol, citric acid, fumaric acid, and sebacic acid. Two-step heating processes for preparing the high molecular weight polyesters are also provided. | 09-15-2011 |