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Bigio
Alberto Lee Bigio, Barranquilla CO
| Patent application number | Description | Published |
|---|---|---|
| 20100251499 | Thermal Hairbrush - The thermal brush is used with a hair dryer. The brush includes an elongated bristle retaining core which is mounted at an interior location within a cage forward by a plurality of metal rods. The bristles extend outboard from the core beyond the rod cage and the bristles and the cage form a hourglass shape (a dual frustoconical shape with smaller radial portions adjacent each other). Sometimes, a central region with a constant radial dimension is disposed intermediate the larger radial segments of the cage and bristle brush periphery. At one end, the core and the elongated cage are maintained in a spaced apart relationship by a terminal end cap. A cap at the handle end of the brush also holds the cage and core. The spacing between the metal rods is important as the diameter of the rods. | 10-07-2010 |
Eileen H. Bigio, Riverside, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20080306074 | Compositions Comprising Addl Receptors, Related Compositions, and Related Methods - Disclosed and claimed herein are compositions comprising ADDL receptors, related compositions, and related methods. ADDL receptors are typically, but perhaps not exclusively, localized at the post-synaptic density (PSD) of neuronal cells. Related compositions include, but are not limited to, compounds that affect, positively or negatively, ADDL binding to neuronal cells, either via one or more receptors localized at the post-synaptic density (PSD) or otherwise. Related methods include, but are not limited to, procedures to screen for compounds that affect, either positively or negatively, ADDL binding to neuronal cells, either via one or more receptors localized at the post-synaptic density (PSD) or otherwise. Other related methods include, but are not limited to, prevention and treatment of ADDL-related diseases, such as Alzheimer's disease, mild cognitive impairment, Down's syndrome, and the like, using compositions that inhibit, block, or otherwise interfere with ADDL binding to one or more receptors localized at the post-synaptic density of neuronal cells. | 12-11-2008 |
Irving Bigio, Chestnut Hill, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090326384 | Device With Integrated Multi-Fiber Optical Probe and Methods of Use - Biopsy instruments are integrated with a multi-fiber optical probe adapted to perform diagnostic measurements. In addition to being able to analyze, treat or remove tissue, such integrated devices characterize tissue by measuring the amount of scattering and absorption of light transmitted into the tissue. Each fiberoptic probe has an illuminating fiber that provides a broadband light source for transmission into tissue, and a collecting fiber that collects the light scattered by the tissue and transmits the collected light to a spectrometer. One embodiment is an endoscope-mediated tool with a jaw-type biopsy forceps and a multi-fiber optical probe which is conveyed through a hollow central channel. Another embodiment is an endoscope-mediated tool with a jaw-type biopsy forceps and a plurality of multi-fiber optical probes. Yet another embodiment is an endoscopic polypectomy-type snare catheter with a multi-fiber optical probe located at the tip. | 12-31-2009 |
| 20110060188 | LOW COST DISPOSABLE MEDICAL FORCEPS TO ENABLE A HOLLOW CENTRAL CHANNEL FOR VARIOUS FUNCTIONALITIES - The present invention relates to an endoscopic biopsy forceps ( | 03-10-2011 |
Irving J. Bigio, Chestnut Hill, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100042005 | DETECTING OPTICAL PROPERTIES OF A TURBID MEDIUM - A device for measuring light scattering and absorption properties of a tissue, the device comprising: a probe comprising first and second optical fibers for irradiation and detection. The optical fibers are substantially parallel to each other at the distal end, and are separated by a distance of less than 2 mm, wherein said first and second optical fibers are arranged in said probe at an angle, 6=10 deg. to 45 deg., to the plane perpendicular to the distal end of said probe and wherein the tips of the optical fibers at the distal end are polished parallel to the plane perpendicular to the distal end of said probe. | 02-18-2010 |
Massimo Bigio, Siena IT
| Patent application number | Description | Published |
|---|---|---|
| 20100239600 | CONJUGATE PURIFICATION - This application relates to methods for the purification of saccharide antigen-carrier protein conjugates. In particular, the invention provides a method for purifying saccharide antigen- carrier protein conjugates from free carrier protein, such as CRM1 97, using hydroxyapatite. The invention further relates to methods of preparing vaccines, using this method. | 09-23-2010 |
Robin Bigio, London GB
| Patent application number | Description | Published |
|---|---|---|
| 20100065456 | CASSETTE FOR STORAGE OF MEDICAL INSTRUMENTS | 03-18-2010 |