| Patent application number | Description | Published |
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| 20100209543 | COMPOSITIONS AND METHODS OF USE - This invention relates to the use of plant extracts, compositions thereof, and compounds isolated from plant extracts or obtained from synthetic means thereof, for the treatment of diseases, disorders or symptoms thereof (e.g., proliferation disorders, cancer). | 08-19-2010 |
| 20110027277 | PREDICTIVE MARKER FOR TOPOISOMERASE I INHIBITORS - The present invention generally relates to the fields of cancer therapy and cancer prevention. More particularly, the present invention generally relates to a diagnostic marker for predicting the efficacy of topoisomerase I (topo I) inhibitors in the treatment of cancers. More specifically, the present invention relates to methods, machines, computer systems, computable readable media and kits which can be used to identify and determine the effectiveness of topoisomerase I (topo I) inhibitors in the treatment of cancers, and in some embodiments, the level of sensitivity or resistance of a tumor cell to a topoisomerase I inhibitor, such as camptothecin (CPT), or CTP analogues such as topotecan and irinotecan and derivatives thereof. More specifically, the present invention related to methods, machines, computer systems, computable readable media and kits which can be used to determine the presence of phosphorylation of topoisomerase I polypeptide, in some embodiments phosphorylation at residue serine 10 (S10) of a topoisomerase I polypeptide, wherein the presence of phosphorylation, in particular the phosphorylation at serine 10 of a topoI polypeptide indicates a cancer is likely to be unresponsive to a topo I inhibitor, whereas the absence of phosphorylation, in particular, the absence of phosphorylation at residue serine 10 (S10) identifies a cancer is likely to be responsive to a topo I inhibitor. Other aspect of the present invention relate to phospho-serine 10 topoisomerase I antibodies and other protein binding moieties, and uses thereof. | 02-03-2011 |
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| 20120066145 | Automating A Governance Process Of Reviewing Service Artifacts In A Governed SOA - Modeling the governance process of reviewing service artifacts associated with a service in the SOA and generating, in dependence upon the modeled governance process, one or more automation modules, each automation module including a module of computer program instructions that, when executed by a computer processor, supports performance of one or more steps of the modeled governance process, where the modeled governance process includes preparing one or more service artifacts associated with the service for review, submitting the service artifacts for review, and reviewing the service artifacts. | 03-15-2012 |
| 20120066146 | Automating A Governance Process Of Investigating Service Reuse In A Governed SOA - Modeling a governance process of investigating service reuse in a governed SOA and generating, in dependence upon the modeled governance process, one or more automation modules, each automation module including a module of computer program instructions that, when executed by a computer processor, supports performance of one or more steps of the modeled governance process, where the modeled governance process includes receiving a specification of service requirements, interpreting the service requirements against a registry of deployed services including determining whether a deployed service meets the service requirements, and if a deployed service meets the requirements, initiating a subscription to the deployed service. | 03-15-2012 |
| 20120066147 | Automating A Governance Process Of Optimizing A Portfolio Of Services In A Governed SOA - Modeling a governance process of optimizing a portfolio of services in a governed SOA and generating, in dependence upon the modeled governance process, one or more automation modules, each automation module including a module of computer program instructions that supports performance of one or more steps of the modeled governance process, where the modeled governance process includes determining whether a collection of service artifacts matches one or more service artifacts stored in a service registry; if no service artifacts stored in the service registry match the collection of service artifacts, initiating creation of a service in accordance with the collection of service artifacts; if one or more service artifacts stored in the service registry match the collection of service artifacts: selecting, in dependence upon predefined action selection criteria, a service administration action to perform; obtaining approval of the selected service administration action; and initiating the selected service administration action. | 03-15-2012 |
| 20120066663 | Modeling A Governance Process Of Establishing A Subscription To A Deployed Service In A Governed SOA - Modeling a governance process of establishing a subscription to a deployed service in a governed Service Oriented Architecture (‘SOA’) and generating, in dependence upon the modeled governance process, one or more automation modules, each automation module comprising a module of computer program instructions that, when executed by a computer processor, supports performance of one or more steps of the modeled governance process, where the modeled governance process includes collecting available service artifacts associated with a deployed service; determining whether the deployed service meets predefined functional requirements; if the deployed service meets the predefined functional requirements, determining whether the deployed service meets predefined non-functional requirements if the deployed service meets the predefined non-functional requirements, creating a subscription request; requesting approval of the subscription request; and if approval is received, creating a subscription to the deployed service. | 03-15-2012 |
| 20120066671 | Automating A Governance Process Of Creating A New Version Of A Service In A Governed SOA - Modeling a governance process of creating a new version of a service in a governed SOA and generating, in dependence upon the modeled governance process, automation modules that include modules of computer program instructions that, when executed by a computer processor, support performance of one or more steps of the modeled governance process and where the modeled governance process includes reviewing requested updates to a deployed service; determining, in dependence upon the requested updates and a specification of a present version of the deployed service, whether a new version of the deployed service is required; if a new version of the deployed service is required, determining whether the present version of the deployed service will be subsumed by the new version; and if the present version of the deployed service will be subsumed by the new version, retiring the present version of the deployed service. | 03-15-2012 |
| Patent application number | Description | Published |
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| 20080224566 | MULTILAYER CONDUCTIVE ELEMENTS - An article comprises first and second electrically responsive elements having a cutting plane which is perpendicular to an x-dimension for separating the elements. The conductive elements of the conductive layers are alternatingly exposed to one of the two opposing faces of the conductive element. | 09-18-2008 |
| 20110094514 | PATTERNED CHEMICAL SENSOR HAVING INERT OCCLUDING LAYER | 04-28-2011 |
| 20110105637 | ADHESIVE ENCAPSULATING COMPOSITION AND ELECTRONIC DEVICES MADE THEREWITH - Adhesive encapsulating compositions for use in electronic devices such as organic electroluminescent devices, touch screens, photovoltaic devices, and thin film transistors are disclosed herein. The adhesive encapsulating compositions include pressure sensitive adhesives comprising one or more polyisobutylene resins, in combination with optional multifunctional (meth)acrylate monomers and/or optional tackifiers. | 05-05-2011 |
| 20110112492 | WOUND DRESSING WITH MICROPUMP - A composite wound dressing apparatus promotes healing of a wound via the use of a micropump system. The micropump system includes a micropump that applies a subatmospheric pressure to the wound to effectively draw wound fluid or exudate away from the wound bed, or deliver fluids to the wound bed, without the need for a cumbersome external pressure (e.g. vacuum) source. Hence, the wound dressing and micropump system is portable which allows the patient mobility that is unavailable when an external vacuum source is used. | 05-12-2011 |
| 20110135921 | Antistatic Block Copolymer Pressure Sensitive Adhesives and Articles - An antistatic pressure sensitive adhesive composition, useful in electronic and optical display applications, comprising an antistatic agent and a first block copolymer comprising at least two hard A block polymeric units each independently having a Tg of at least 50° C., and at least one soft B block (meth)acrylic polymeric unit having a Tg no greater than 20° C. The composition can comprise a second block copolymer. Articles comprising an antistatic pressure sensitive adhesive composition adjacent a first surface of a substrate. | 06-09-2011 |
| 20110135922 | Adhesive Compositions with Multiple Tackifiers - Adhesive compositions and articles that contain these adhesive compositions are described. More particularly, the adhesive compositions include (a) a block copolymer prepared from monoethylenically unsaturated monomers and (b) a tackifier mixture. The adhesives compositions can be adhered to many substrates including those having a non-polar surface. | 06-09-2011 |
| 20110254408 | Electroactive Polymers and Articles Containing Them - An electroactive polymer device is described that includes at least one layer of a dielectric polymer that is a polymerized product of at least one ethylenically unsaturated nitrogen-containing monomer. Also disclosed is a transducer that includes the electroactive polymer as disclosed. | 10-20-2011 |
| 20110257316 | ACRYLIC BLOCK COPOLYMERS FOR AEROSOLS AND AEROSOL ADHESIVES - An aerosol is described comprising a composition comprising an acrylic block copolymer, a solvent, and a propellant. An article is described comprising the aerosol contained within a pressurized containment vessel comprising a valve. An aerosol mist is also described comprising droplets of an adhesive composition, wherein the adhesive composition comprises an acrylic block copolymer, a glass transition temperature modifier, and optionally an additive. | 10-20-2011 |
| 20110260578 | Electromechanical Materials and Devices Including the Same - An electromechanical article that includes a composite material ( | 10-27-2011 |
| 20110301503 | WEIGHTED BIOACOUSTIC SENSOR AND METHOD OF USING SAME - A sensor for sensing bioacoustic energy includes a housing comprising an interfacing portion configured to establish coupling with a body part during use. The sensor includes a transducer element coupled to the interfacing portion of the housing and configured to sense sounds produced by matter of biological origin. One or more conductors are coupled to the transducer element. A mass element is compliantly coupled to a surface of the transducer element. Intervening material is disposed between the transducer element surface and the mass element, and allows for differential motion between the transducer element surface and the mass element during excitation of the transducer element. | 12-08-2011 |
| 20120064304 | STRETCH RELEASABLE PRESSURE-SENSITIVE ADHESIVES - An adhesive tape that is stretch releasable, articles that contain the adhesive tape, and uses of the adhesive tape are disclosed. The adhesive tape includes a backing layer that is adjacent to at least one pressure-sensitive adhesive layer. The backing layer includes a poly(alkylene)copolymer. Each pressure-sensitive adhesive layer includes a polyisobutylene material. The adhesive tapes can be optically clear. | 03-15-2012 |
