Bestwick
Charles Stuart Bestwick, Aberdeenshire GB
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20100151508 | COMPOUNDS - Flavonoid-type compounds of the Formula (II); in which R | 06-17-2010 |
Joshua E. Bestwick, Seattle, WA US
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20080300982 | METHOD FOR ENABLING THE EXCHANGE OF ONLINE FAVORS - Embodiments are directed to enabling the exchange of online favors. In one embodiment, the system may include a client device connected via a network to a favor management platform. The favor management platform may include a favor management server, web server, billing server, and an advertisement server. A user may enter information detailing a favor to be asked or to be offered. The user further may specify the reward for the favor, including non-monetary rewards, such as good will. The user also specifies whom to send the request or offer for the favor. The favor management server generates favor page, with the set of contacts. A notification message regarding the favor page is sent to the set of specified contacts. Once received, a contact may view the favor page, providing comments and/or responses. The user may provide the reward to a contact(s) that satisfy the favor. | 12-04-2008 |
Michael Bestwick, Ripley GB
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20100296937 | BALANCED ROTOR FOR A TURBINE ENGINE - A balanced rotor of a turbine engine, having a rotor disc with a circumferential slot and a row of rotor blades mounted in the slot and a balance weight having a land which extends beneath the root of a blade and having a mass-adjustment protrusion extending from the land in a radial direction relative to the axis of the rotor component and which lies wholly between the blade root and an adjacent blade root. | 11-25-2010 |
Richard Bestwick, Penyffordd GB
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20120073137 | AIRCRAFT RIB-SPAR JOINT - A method of forming a rib-spar joint during assembly of an aircraft wing, the method comprising: providing a spar with a fixedly attached rib post, the rib post having a first coordination feature; providing a rib having a web with a first tooling feature; providing a tooling component having a second tooling feature for cooperating with the first tooling feature, a second coordination feature for cooperating with the first coordination feature, and a plurality of drill bushings; fixedly attaching the tooling component to the rib web by aligning the first and second tooling features; aligning the rib with the spar by aligning the first and second coordination features; drilling fastener holes in the rib and the rib post off the drill bushings of the tooling component; removing the tooling component from the rib web; and fastening the rib to the rib post using the fastener holes to form a rib-spar joint. The method may be applied to form front and/or rear rib-spar joints. | 03-29-2012 |
Richard K. Bestwick, Corvallis, OR US
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20080199961 | ANTISENSE COMPOSITION AND METHOD FOR INHIBITION OF miRNA BIOGENESIS - The present disclosure relates to compounds and methods for inhibiting the formation of miRNAs that inhibit translation of one or more identified proteins. The compounds comprise antisense oligonucleotides targeting the pri-miRNA precursor of miRNAs. | 08-21-2008 |
20090012280 | OLIGONUCLEOTIDE COMPOUND AND METHOD FOR TREATING NIDOVIRUS INFECTIONS - A method and oligonucleotide compound for inhibiting replication of a nidovirus in virus-infected animal cells are disclosed. The compound (i) has a nuclease-resistant backbone, (ii) is capable of uptake by the infected cells, (iii) contains between 8-25 nucleotide bases, and (iv) has a sequence capable of disrupting base pairing between the transcriptional regulatory sequences in the 5′ leader region of the positive-strand viral genome and negative-strand 3′ subgenomic region. In practicing the method, infected cells are exposed to the compound in an amount effective to inhibit viral replication. | 01-08-2009 |
20140315977 | EXON SKIPPING COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY - Antisense molecules capable of binding to a selected target site in the human dystrophin gene to induce exon 53 skipping are described. | 10-23-2014 |
20140323544 | EXON SKIPPING COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY - Antisense molecules capable of binding to a selected target site in the human dystrophin gene to induce exon 44 skipping are described. | 10-30-2014 |
20140329881 | EXON SKIPPING COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY - Antisense molecules capable of binding to a selected target site in the human dystrophin gene to induce exon 44 skipping are described. | 11-06-2014 |
Richard Keith Bestwick, Corvallis, OR US
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20140024821 | OLIGONUCLEOTIDE ANALOGUES TARGETING HUMAN LMNA - Provided are LMNA-targeted antisense oligonucleotides for reducing expression of one or more aberrantly spliced LMNA mRNA isoforms that encode progerin. | 01-23-2014 |