Bes
Alexandre Bes, Vourey FR
Patent application number | Description | Published |
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20100252067 | Cleaning device and cleaning process for a plasma reactor - The invention concerns a device and a process, the device being a cleaning device utilizing a dry chemical means assisted by plasma from a reactor ( | 10-07-2010 |
20110215722 | DEVICE AND METHOD FOR PRODUCING AND/OR CONFINING A PLASMA - The invention relates to a device for producing and/or confining a plasma ( | 09-08-2011 |
20140305467 | CLEANING DEVICE AND CLEANING PROCESS FOR A PLASMA REACTOR - The invention concerns a device and a process, the device being a cleaning device utilizing a dry chemical means assisted by plasma from a reactor ( | 10-16-2014 |
Cédric Bes, Ambilly FR
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20100092455 | NOVEL ANTI-PROLIFERATION ANTIBODIES - The present invention relates to novel isolated antibodies, or the derived compounds or functional fragments of same, capable of inhibiting the proliferation of tumor cells in vitro and/or in vivo, said antibodies having been obtained by functional screening. | 04-15-2010 |
20110003705 | NOVEL METHOD FOR GENERATING AND SCREENING AN ANTIBODY LIBRARY - The invention relates to a method for generating a DNA sequence coding for the heavy chain or the light chain of at least one antibody from RNA from a cell capable of producing an antibody. More particularly, the invention relates to the generation of a monoclonal antibody library. The invention also relates to the use of an antibody library for screening monoclonal antibodies, preferably human antibodies for treating cancer. | 01-06-2011 |
Cédric Bes, Madrid FR
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20150291696 | ANTI-cMET ANTIBODY - Antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor, with an improved antagonistic activity, said antibody comprising a modified hinge region. A composition comprising such an antibody antagonist to c-Met and its use as a medicament for treating cancer. | 10-15-2015 |
Cédric Bes, Nantes FR
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20130109841 | ANTI-cMET ANTIBODY | 05-02-2013 |
Cédric Bes, Madrid ES
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20130303734 | NOVEL HOMOGENEOUS HUMANIZED ANTIPROLIFERATION ANTIBODIES - The present disclosure relates to novel humanized antibodies able to inhibit tumor growth, as well as the amino and nucleic acid sequences coding for such antibodies. From one aspect, the disclosure relates to novel anti-JAM-A homogeneous humanized antibodies able to inhibit tumor growth. The disclosure also comprises the use of such antibodies as a drug for the preventive and/or therapeutic treatment of cancers, as well as compositions comprising such antibodies in combination with other anticancer compounds. The disclosure also relates to a method for the preparation of such novel humanized antibodies. | 11-14-2013 |
20160039935 | NOVEL ANTI-cMET ANTIBODY - The present invention relates to a novel divalent antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor, preferably both in a ligand-dependent and in a ligand-independent manner as well as the amino acid and nucleic acid sequences coding for said antibody. More preferably said antibody comprises a modified hinge region and exhibits an improved antagonistic activity. More particularly, the antibody according to the invention is capable of inhibiting the c-Met dimerization. The invention likewise comprises the use of said antibody as a medicament for the prophylactic and/or therapeutic treatment of cancers, preferably for cancer characterized by a ligand-independent activation of c-Met, or any pathology connected with the over expression of said receptor as well as in processes or kits for diagnosis of illnesses connected with the over-expression of c-Met. The invention finally comprises products and/or compositions comprising such an antibody in combination with other antibodies and/or chemical compounds directed against other growth factors involved in tumor progression or metastasis and/or compounds and/or anti-cancer agents or agents conjugated with toxins and their use for the prevention and/or the treatment of certain cancers. | 02-11-2016 |
20160106844 | ALTERNATIVE FORMULATIONS FOR TNFR: FC FUSION POLYPEPTIDES - The present invention relates to aqueous stable pharmaceutical compositions suitable for storage of polypeptides that contain TNFR:Fc. | 04-21-2016 |
Cédric Bes, Villevieille FR
Patent application number | Description | Published |
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20110097262 | NOVEL ANTI-cMET ANTIBODY - The invention relates to a novel antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor both in a ligand-dependent and in a ligand-independent manner, with an improved antagonistic activity, said antibody comprising a modified hinge region. | 04-28-2011 |
20110239316 | ANTI-cMET ANTIBODY - Antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor, with an improved antagonistic activity, said antibody comprising a modified hinge region. A composition comprising such an antibody antagonist to c-Met and its use as a medicament for treating cancer. | 09-29-2011 |
Cédric Bes, Ambilly FR
Patent application number | Description | Published |
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20110003705 | NOVEL METHOD FOR GENERATING AND SCREENING AN ANTIBODY LIBRARY - The invention relates to a method for generating a DNA sequence coding for the heavy chain or the light chain of at least one antibody from RNA from a cell capable of producing an antibody. More particularly, the invention relates to the generation of a monoclonal antibody library. The invention also relates to the use of an antibody library for screening monoclonal antibodies, preferably human antibodies for treating cancer. | 01-06-2011 |
20120156191 | ANTI-JAM-A ANTIBODIES - The present invention relates to novel isolated antibodies, derived compounds, and functional isolated antibody fragments, capable of inhibiting the proliferation of tumor cells in vitro and/or in vivo and obtained by functional screening. | 06-21-2012 |
Cédric Bes, Madrid ES
Patent application number | Description | Published |
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20130303734 | NOVEL HOMOGENEOUS HUMANIZED ANTIPROLIFERATION ANTIBODIES - The present disclosure relates to novel humanized antibodies able to inhibit tumor growth, as well as the amino and nucleic acid sequences coding for such antibodies. From one aspect, the disclosure relates to novel anti-JAM-A homogeneous humanized antibodies able to inhibit tumor growth. The disclosure also comprises the use of such antibodies as a drug for the preventive and/or therapeutic treatment of cancers, as well as compositions comprising such antibodies in combination with other anticancer compounds. The disclosure also relates to a method for the preparation of such novel humanized antibodies. | 11-14-2013 |
Cédric Bes, Villevieille FR
Patent application number | Description | Published |
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20110097262 | NOVEL ANTI-cMET ANTIBODY - The invention relates to a novel antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor both in a ligand-dependent and in a ligand-independent manner, with an improved antagonistic activity, said antibody comprising a modified hinge region. | 04-28-2011 |
20140112911 | NOVEL ANTI-CMET ANTIBODY - The present invention relates to a novel divalent antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor, preferably both in a ligand-dependent and in a ligand-independent manner as well as the amino acid and nucleic acid sequences coding for said antibody. More preferably said antibody comprises a modified hinge region and exhibits an improved antagonistic activity. More particularly, the antibody according to the invention is capable of inhibiting the c-Met dimerization. The invention likewise comprises the use of said antibody as a medicament for the prophylactic and/or therapeutic treatment of cancers, preferably for cancer characterized by a ligand-independent activation of c-Met, or any pathology connected with the over expression of said receptor as well as in processes or kits for diagnosis of illnesses connected with the over-expression of c-Met. The invention finally comprises products and/or compositions comprising such an antibody in combination with other antibodies and/or chemical compounds directed against other growth factors involved in tumor progression or metastasis and/or compounds and/or anti-cancer agents or agents conjugated with toxins and their use for the prevention and/or the treatment of certain cancers. | 04-24-2014 |
20140115727 | NOVEL ANTI-cMET ANTIBODY - The invention relates to a novel antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor both in a ligand-dependent and in a ligand-independent manner, with an improved antagonistic activity, said antibody comprising a modified hinge region. | 04-24-2014 |
20150307613 | NOVEL ANTI-cMET ANTIBODY - The invention relates to a novel antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor both is a ligand-dependent and in a ligand-independent manner, with an improved antagonistic activity, said antibody comprising a modified hinge region. | 10-29-2015 |
Claude Bes, Montpellier FR
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20120264082 | DEVICE AND METHOD INTENDED FOR HOLDING A PROSTHESIS IN DENTAL IMPLANTOLOGY - The invention relates to a device intended for connecting a prosthesis to a dental implant or directly to the jawbone of a patient, of the type including a pier ( | 10-18-2012 |
20130345028 | FITNESS DEVICE AND PRODUCTION METHOD - The invention relates to a fitness device for exercising the lower limbs, characterised in that the pedals ( | 12-26-2013 |
Goran Bes, Zagreb HR
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20150087188 | CONNECTOR | 03-26-2015 |
Guillaume Bes, Moirans FR
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20100212855 | CASTING PROCESS FOR ALUMINUM ALLOYS - The invention relates to a casting process for an aluminum alloy containing at least about 0.1% of Mg and/or at least about 0.1% of Li in which a liquid surface of said alloy is put into contact with a dried gas including at least about 2% of oxygen by volume and with a water partial pressure lower than about 150 Pa throughout most of the solidification process. | 08-26-2010 |
20110209843 | CASTING PROCESS FOR ALUMINUM ALLOYS - The present invention relates to a casting process for an aluminum alloy containing at least about 0.1% of Mg and/or at least about 0.1% of Li in which a liquid surface of said alloy is put into contact with a dried gas including at least about 2% of oxygen by volume and with a water partial pressure lower than about 150 Pa throughout most of the solidification process. The invention makes it possible to cast the most oxidable aluminum alloys, in particular aluminum alloys containing magnesium and/or lithium, without using additives such as beryllium and/or calcium and without using expensive devices and/or gases, to obtain cast ingots generally free from surface defects and pollution, in complete safety. | 09-01-2011 |
Laurence Bes, Montpellier FR
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20100277778 | METALLISED HOLOGRAPHIC FILM AND PROCESS FOR ITS MANUFACTURE - A metallised film includes at least one reflective layer ( | 11-04-2010 |
20110226147 | Method of producing a transparent polychromatic printed iridescent image - A method of producing a transparent polychromatic printed iridescent image ( | 09-22-2011 |
Laurence Bes, Jacou FR
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20160089920 | THERMOCHROMIC INK COMPOSITION - A thermochromic ink composition includes, in a liquid medium, known as solvent, a dispersion of thermochromic microcapsules incorporating at least one leuco-dye and a thermoplastic binder selected from the group containing polyacrylic polyesters, polyurethanes and copolymers thereof. The composition is characterised in that the solvent is aprotic. A a method for producing a card and such a card incorporating at least one thermochromic pattern produced with a thermochromic ink composition are also described. | 03-31-2016 |
20160089923 | METHOD AND DEVICE FOR THE SECURE PROTECTION OF AN OFFICIAL DOCUMENT AND OFFICIAL DOCUMENT THUS PROTECTED - A method for the secure protection of a portion of the surface of an official document bearing markings, in which: a transparent security layer ( | 03-31-2016 |
Magali Bes, Saint Marcel Sur Aude FR
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20140263767 | METHOD AND DEVICE FOR DYNAMICALLY TREADING FRUIT - Dynamic crusher for treading fruit, particularly grapes, with a treading chamber having, when considering the direction of the path followed by the fruit in the crusher, an upstream fruit-introduction opening, a downstream discharge opening for discharging the must that results from the treading, a rotary ejector that allows kinetic energy to be imparted to the fruit introduced into the treading chamber, and allows the fruit to be cast against a fixed fruit-bursting wall, wherein the rotary ejector is mounted such that it can rotate about a vertical axis and a fixed fruit-bursting wall is positioned around the rotary ejector or facing the peripheral edge thereof against which fruit is cast, rotation of which allows the fruit to be cast, under the effect of centrifugal force, against the fixed fruit-bursting wall, causing the fruit to burst. A method for dynamically treading fruit using such a crusher is also disclosed. | 09-18-2014 |
Rene Bes, Castanet Tolosan FR
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20100258445 | METHOD FOR THE PRODUCTION OF AN ORDERED POROUS STRUCTURE FROM AN ALUMINIUM SUBSTRATE - A method for making a porous structure, includes producing, by anodization of an aluminum substrate, an outer surface layer ( | 10-14-2010 |