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Bertrand Pain
Bertrand Pain, Nohanent FR
| Patent application number | Description | Published |
|---|---|---|
| 20110010783 | METHOD FOR REPROGRAMMING IN VITRO STEM CELLS AND SOMATIC CELLS INTO GERMINAL CELLS - The present invention is related to a method for inducing in vitro the differentiation of stem cells or somatic cells towards germinal cells, comprising the following steps: | 01-13-2011 |
Bertrand Pain, Lyon FR
| Patent application number | Description | Published |
|---|---|---|
| 20090151013 | Modified ES cells and ES cell-specific genes - The invention concerns modified avian ES cells, specifically expressing an exogenous gene when they have a pluripotent character. The invention also concerns a nucleic acid and a polypeptide specifically expressed in pluripotent avian cells, and methods for detecting the pluripotent character of cells using said nucleic acid and polypeptide. | 06-11-2009 |
| 20090239297 | AVIAN CELL LINES USEFUL FOR THE PRODUCTION OF SUBSTRATES OF INTEREST - The present invention relates to a method for producing avian cell lines, comprising gradual or complete withdrawal of growth factors, serum and/or feeder layer so that the established lines are adherent or nonadherent cells capable of proliferating indefinitely in a basic culture medium. The invention also relates to the cells derived from such lines which are particularly useful for the production of substances of interest. | 09-24-2009 |
| 20100221825 | AVIAN CELL LINES USEFUL FOR THE PRODUCTION OF SUBSTANCES OF INTEREST - The present invention relates to a method for producing avian cell lines, comprising gradual or complete withdrawal of growth factors, serum and/or feeder layer so that the established lines are adherent or nonadherent cells capable of proliferating indefinitely in a basic culture medium. The invention also relates to the cells derived from such lines which are particularly useful for the production of substances of interest. | 09-02-2010 |
Bertrand Pain, Clermond-Ferrand FR
| Patent application number | Description | Published |
|---|---|---|
| 20090239286 | PRODUCTION OF POXVIRUSES WITH ADHERENT OR NON ADHERENT AVIAN CELL LINES - The present invention relates to a method for replicating poxviruses such as vaccinia virus comprising the steps of inoculating avian embryonic stem cells with viral particles and culturing said cells in a basal medium until cells lysis occurs and newly produced viral particles are released in said medium. | 09-24-2009 |
| 20100111999 | PRODUCTION OF POXVIRUSES WITH ADHERENT OR NON ADHERENT AVIAN CELL LINES - The present invention relates to a method for replicating poxviruses such as vaccinia virus comprising the steps of inoculating avian embryonic stem cells with viral particles and culturing said cells in a basal medium until cells lysis occurs and newly produced viral particles are released in said medium. | 05-06-2010 |
Bertrand Pain, Clermont-Ferrand FR
| Patent application number | Description | Published |
|---|---|---|
| 20090311682 | COMBINATION OF AVIAN CELL MARKERS - The present invention relates to a novel combination of avian cell markers which make it possible to characterize the said cells according to their phenotype, whether they are StX cells, stem cells or germ cells. The present invention also relates to a method for characterizing avian cells with the said markers, and to a method for culturing avian cells, in which the cells are characterized by the method according to the invention. | 12-17-2009 |
| 20090311789 | METHOD FOR PREPARING DIFFERENTIATED AVIAN CELLS AND GENES INVOLVED IN MAINTAINING PLURIPOTENCY - The present invention relates to a method for preparing differentiated avian cells from stem cells in culture. Genes involved in maintaining the pluripotency of avian stem cells were identified and cloned. By inhibiting the expression of these genes in stem cells, the latter lose their pluripotency characteristics and enter into differentiation. These differentiated cells obtained in vitro can serve as host cells for pathogens, in particular viruses, and can thus be used for the production of antiviral vaccines. | 12-17-2009 |