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Bertino, US

Elisa Bertino, West Lafayette, IN US

Patent application numberDescriptionPublished
20080320549Method and System for Determining Policy Similarities - A method for determining similarity of two policies includes providing a first policy with n rules and a second policy with m rules, wherein each rule is structured into a plurality of identifiable elements, categorizing the rules in each policy based on an action, for each pair of rules finding those predicates whose attribute names match, computing an attribute similarity score for the attribute values, summing the attribute similarity scores for all pairs to obtain an element similarity score, and computing a rule similarity score for the pair of rules from a weighted sum of said element similarity scores.12-25-2008

Jennie Bertino, New York, NY US

Patent application numberDescriptionPublished
20090269998OUTBOARD ENGINE FLUSHING SYSTEM - The outboard engine flushing system frees the boater from need to lean out beyond the boat transom to access the conventional engine cooling flush components. The system includes a Y hose connector attached to the conventional inlet fitting beneath the engine cowling, and a forwardly extending flexible tube attached to another leg of the Y connector. The conventional return line normally connected to the cowl bottom inlet fitting is connected to the remaining leg of the Y connector. A shutoff valve is provided at the forward end of the flexible tube. To flush the cooling system of the engine, the boater connects a conventional water hose to the forward end of the flexible tube extending from the Y connector, opens the valve, and turns on the water. When flushing is complete, the shutoff valve is closed and the water hose disconnected to ready the boat and engine for further operation.10-29-2009

Joseph Bertino, Branford, CT US

Patent application numberDescriptionPublished
20090274671VECTOR ENCODING HUMAN GLOBIN GENE AND USE THEREOF IN TREATMENT OF HEMOGLOBINOPATHIES - Recombinant lentiviral vectors having a region encoding a functional β-globin gene; and large portions of the β-globin locus control regions which include DNase I hypersensitive sites HS2, HS3 and HS4 provides expression of β-globin when introduced into a mammal, for example a human, in vivo. Optionally, the vector further includes a region encoding a dihydrofolate reductase. The vector may be used in treatment of hemoglobinopathies, including β-thalessemia and sickle-cell disease. For example, hematopoietic progenitor or stem cells may be transformed ex vivo and then restored to the patient. Selection processes may be used to increase the percentage of transformed cells in the returned population. For example, a selection marker which makes transformed cells more drug resistant than untransformed cells allows selection by treatment of the cells with the corresponding drug.11-05-2009

Joseph R. Bertino, Brantford, CT US

Patent application numberDescriptionPublished
20120093919E2F AS A TARGET OF HORMONE REFRACTORY PROSTATE CANCER - The instant invention provides amino acid sequences competing with E2F for DNA binding. Methods of using said amino acid sequences for treatment of hormone-refractory prostate cancer are also provided.04-19-2012

Joseph R. Bertino, New Brunswick, NJ US

Joseph R. Bertino, Branford, CT US

Patent application numberDescriptionPublished
20100151004MODULATION OF DRUG SENSITIVITY - Methods for the treatment of disorders, including cancer, are described which include administering to a subject a DNA methylation inhibitor and an antineoplastic agent. Compositions containing a DNA methylation inhibitor and an antineoplastic agent, which are useful in treating disorders including cancer, are also described. Additionally, methods useful for developing a prognosis for or diagnosing a subject's development of resistance to treatment with a chemotherapeutic agent are described.06-17-2010
20110020291USE OF STEM CELLS FOR WOUND HEALING - Cells, compositions, and methods of cell therapy for administering a therapeutically effective amount of stem cells or cell concentrate to achieve accelerated wound healing of normal and chronic wounds, while minimizing the formation of scar tissue.01-27-2011

Patent applications by Joseph R. Bertino, Branford, CT US

Joseph Rocco Bertino, New Brunswick, NJ US

Patent application numberDescriptionPublished
20100240595Improved Antitumoral Treatments - The present invention relates to combinations of Aplidine with Gemcitabine, and the use of these combinations in the treatment of cancer.09-23-2010

Joseph S. Bertino, Schenectady, NY US

Patent application numberDescriptionPublished
20110171284POVIDONE-IODINE AND SUCROSE WOUND HEALING DRESSING - The present invention relates to a composition and wound dressing for delivering a composition comprising povidone-iodine and sucrose mixture. The composition is gelled and, in one embodiment, is impregnated on a gauze or other like material for application to an exuding or non-exuding wound.07-14-2011

Robert J. Bertino, New York, NY US

Patent application numberDescriptionPublished
20090269998OUTBOARD ENGINE FLUSHING SYSTEM - The outboard engine flushing system frees the boater from need to lean out beyond the boat transom to access the conventional engine cooling flush components. The system includes a Y hose connector attached to the conventional inlet fitting beneath the engine cowling, and a forwardly extending flexible tube attached to another leg of the Y connector. The conventional return line normally connected to the cowl bottom inlet fitting is connected to the remaining leg of the Y connector. A shutoff valve is provided at the forward end of the flexible tube. To flush the cooling system of the engine, the boater connects a conventional water hose to the forward end of the flexible tube extending from the Y connector, opens the valve, and turns on the water. When flushing is complete, the shutoff valve is closed and the water hose disconnected to ready the boat and engine for further operation.10-29-2009