| Patent application number | Description | Published |
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| 20080268486 | DUAL MEASUREMENT ANALYTE DETECTION SYSTEM - An analyte detection system is configured to measure concentrations of at least first and second analytes in a single material sample supported by a sample element. The measurement of a second analyte can be conditioned on a quantitative or qualitative result of the first measurement. In one embodiment, the first analyte is glucose and the second analyte is a ketone. According to such an embodiment the ketone is measured if the result of the glucose measurement exceeds a previously-specified value or falls outside of a previously-specified range. | 10-30-2008 |
| 20080269616 | MIR SPECTROSCOPY OF TISSUE - Disclosed are methods of determining long-term deposition pattern of a compound in tissue. The following steps can be followed: placing tissue against a receptor; directing mid-infrared electromagnetic radiation onto the tissue; quantifying the electromagnetic radiation that is reflected from the tissue to obtain a reflected amount; using a calibration equation to calculate the concentration of a compound from the reflected amount; and using the concentration of the compound to evaluate presence of a clinical condition in the tissue. | 10-30-2008 |
| 20090030296 | Predictive oximetry model and method - The invention comprises a method for determining oxygen saturation in a subject, comprising the steps of compiling a data base of measured spectral data that includes pulsatile AC and non-pulsatile DC components, and spectral values of oxyhemoglobin (oxyHb) and deoxyhemoglobin (deoxyHb); determining absorbed pulsatile components and non-pulsatile components as a function of the oxyHb and deoxyHb values; determining total pulsatile and non-pulsatile optical density as a function of the absorbed pulsatile and non-pulsatile components; determining a mathematical relationship between at least one pulsatile AC parameter and at least one non-pulsatile DC parameter; and estimating oxygen saturation based on the mathematical relationship. | 01-29-2009 |
| 20090045342 | METHOD AND APPARATUS FOR DETERMINING AN ANALYTE CONCENTRATION IN A SAMPLE HAVING INTERFERENTS - A method and apparatus are described that permit an analyte concentration to be estimated from a measurement in the presence of compounds that interfere with the measurement. The method reduces the error in the analyte concentration in the presence of interferents. The method includes the use of a set of measurements obtained for a large population having a range of known analyte and interfering compound concentrations. From a sample measurement, which may or may not be one of the population, likely present interferents are identified, and a calibration vector is calculated. | 02-19-2009 |
| 20090187110 | Method for determining a cardiac function - A method for determining a cardiac function, comprising (i) determining base anatomical characteristics associated with the subject, (ii) determining pulse delay to a first body site (PD | 07-23-2009 |
| 20090213360 | DEVICE AND METHOD FOR IN VITRO DETERMINATION OF ANALYTE CONCENTRATION WITHIN BODY FLUIDS - A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band. | 08-27-2009 |
| 20100049007 | Integrated physiological sensor apparatus and system - A physiological sensor apparatus, system and method for determining a physiological characteristic, comprising providing at least one physiological sensor that is adapted to measure at least one physiological characteristic at a target measurement site on a subject's body, heating an extended tissue region on the subject's body, whereby blood perfusion of the tissue region is enhanced, and measuring at least one physiological characteristic at the target measurement site with the physiological sensor during or within a predetermined period after heating the extended tissue region. In one embodiment, the sensor system includes at least one temperature algorithm that is adapted to adjust the heat applied to the extended tissue region based on the body's response to the heat stimuli. | 02-25-2010 |
| 20100049023 | Non-invasive method and system for determining physiological characteristics - A non-invasive method of determining a physiological characteristic, comprising providing at least one physiological sensor that is adapted to measure at least one physiological characteristic at a target measurement site on a subject's body, heating an extended tissue region on the subject's body, whereby blood perfusion of the tissue region is enhanced, and measuring at least one physiological characteristic with the physiological sensor during or within a predetermined period after heating the extended tissue region. | 02-25-2010 |
| 20100152547 | Method and system for determining cardiac performance - Methods and associated algorithms for determining cardiac and/or cardiovascular performance that are based on at least one cardiac function determinant associated with or at least in part, reflective of preload, contractility and afterload. | 06-17-2010 |
| 20100221762 | METHOD AND APPARATUS FOR DETERMINING AN ANALYTE CONCENTRATION IN A SAMPLE HAVING INTERFERENTS - A method and apparatus are described that permit an analyte concentration to be estimated from a measurement in the presence of compounds that interfere with the measurement. The method reduces the error in the analyte concentration in the presence of interferents. The method includes the use of a set of measurements obtained for a large population having a range of known analyte and interfering compound concentrations. From a sample measurement, which may or may not be one of the population, likely present interferents are identified, and a calibration vector is calculated. | 09-02-2010 |
| 20100234703 | METHOD AND APPARATUS FOR DETECTION OF MULTIPLE ANALYTES - In some embodiments, an apparatus analyzes the composition of bodily fluid. The apparatus comprises a fluid handling network including a patient end configured to maintain fluid communication with a bodily fluid in a patient and at least one pump intermittently operable to draw a sample of bodily fluid from the patient. The apparatus further comprises a fluid analyzer positioned to analyze at least a portion of the sample and measure the presence of two or more analytes. Also disclosed is a method for analyzing the composition of a bodily fluid in a patient. The method comprises drawing a sample of the bodily fluid of the patient through a fluid handling network configured to maintain fluid communication with a bodily fluid in a patient. The method further comprises analyzing the at least a portion of the sample in a fluid analyzer to estimate the concentration of two or more analytes in the sample. | 09-16-2010 |
| 20100240964 | SYSTEM AND METHOD FOR DETERMINING A TREATMENT DOSE FOR A PATIENT - In certain embodiments, a method of maintaining health of a patient uses an analyte detection system. The analyte detection system is coupled to the patient such that a bodily fluid of the patient is accessible to the analyte detection system. The method includes automatically initiating and conducting a measurement of an analyte in the bodily fluid using the analyte detection system. The method further includes determining a treatment dose for the patient based on the measurement using the analyte detection system. | 09-23-2010 |
| 20100249547 | VITRO DETERMINATION OF ANALYTE LEVELS WITHIN BODY FLUIDS - A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band. | 09-30-2010 |
| 20110111449 | IN VITRO DETERMINATION OF ANALYTE LEVELS WITHIN BODY FLUIDS - A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band. | 05-12-2011 |
| 20110112383 | Devices, systems and methods for treatment of eating disorders - An ingestible gastric device comprising a formed body that is adapted to expand upon exposure to a hydration medium and then degrade after a first residence time in the stomach cavity, allowing the device to be passed by the patient's normal digestive process, and monitoring means for monitoring the gastric device. In some embodiments, the monitoring means comprises a biocompatible RFID tag. | 05-12-2011 |
