Patent application number | Description | Published |
20080290715 | MODULAR PASSENGER SEAT FOR AN AIRCRAFT - An aircraft passenger seat assembly as described herein is formed from two primary and modular components: a structural frame that provides passenger support and dynamic load paths for the seat assembly; and a comfort frame that provides the passenger seating surface and the external upholstery layer for the seat assembly. If the seat assembly is designed for multiple passengers, then a separate comfort frame is used for each passenger seat location. The structural frame can be formed as a molded composite construction, and the comfort frame can also utilize a molded composite support frame. The support frame is used as a mounting shell for a fabric carrier that includes the external upholstery layer. The modular design and use of composite materials results in a significant weight and parts count savings relative to conventional seat designs. | 11-27-2008 |
20110101165 | MODULAR PASSENGER SEAT FOR AN AIRCRAFT - An aircraft passenger seat assembly as described herein is formed from two primary and modular components: a structural frame that provides passenger support and dynamic load paths for the seat assembly; and a comfort frame that provides the passenger seating surface and the external upholstery layer for the seat assembly. If the seat assembly is designed for multiple passengers, then a separate comfort frame is used for each passenger seat location. The structural frame can be formed as a molded composite construction, and the comfort frame can also utilize a molded composite support frame. The support frame is used as a mounting shell for a fabric carrier that includes the external upholstery layer. The modular design and use of composite materials results in a significant weight and parts count savings relative to conventional seat designs. | 05-05-2011 |
20110304251 | FURNITURE COMPONENT WITH FLOATING TOP - A furniture component includes a base having a back wall with a first outer vertical face, a first inner vertical face and a first upper edge. A pair of horizontally spaced apart side walls each have a second outer vertical face, a second inner vertical face and a second upper edge. The first and second upper edges are substantially coplanar. An outer top includes a bottom surface spaced above the first and second upper edges and defines a visible gap therebetween. The outer top has a rear edge and a pair of horizontally spaced apart side edges. The rear edge and the first outer vertical face are substantially coplanar, and the side edges and second outer vertical faces are substantially coplanar. A method of assembling and using the furniture component are also provided. | 12-15-2011 |
20120138744 | MODULAR PASSENGER SEAT FOR AN AIRCRAFT - An aircraft passenger seat assembly as described herein is formed from two primary and modular components: a structural frame that provides passenger support and dynamic load paths for the seat assembly; and a comfort frame that provides the passenger seating surface and the external upholstery layer for the seat assembly. If the seat assembly is designed for multiple passengers, then a separate comfort frame is used for each passenger seat location. The structural frame can be formed as a molded composite construction, and the comfort frame can also utilize a molded composite support frame. The support frame is used as a mounting shell for a fabric carrier that includes the external upholstery layer. The modular design and use of composite materials results in a significant weight and parts count savings relative to conventional seat designs. | 06-07-2012 |
Patent application number | Description | Published |
20140288275 | NOVEL HETERODIMERIC PROTEINS - The invention provides novel heterodimeric proteins including heterodimeric antibodies. | 09-25-2014 |
20140294835 | NOVEL HETERODIMERIC PROTEINS - The invention provides heterodimeric antibodies comprising a first heavy chain comprising a first Fc domain and a single chain Fv region that binds a first antigen. The heterodimeric antibodies also comprise a second heavy chain comprising a second Fc domain, a first variable heavy chain and a first variable light chain, wherein the first and second Fc domains are different. | 10-02-2014 |
20140322217 | NOVEL HETERODIMERIC PROTEINS - The invention provides heterodimeric antibodies comprising a first heavy chain comprising a first Fc domain and a single chain Fv region that binds a first antigen. The heterodimeric antibodies also comprise a second heavy chain comprising a second Fc domain, a first variable heavy chain and a first variable light chain, wherein the first and second Fc domains are different. | 10-30-2014 |
20140363426 | HETERODIMERIC PROTEINS - In one aspect, the present invention provides heterodimeric antibodies comprising a first monomer comprising a first heavy chain constant domain comprising a first variant Fc domain and a first antigen binding domain and a second monomer comprising a second heavy chain constant domain comprising a second variant Fc domain and a second antigen binding domain. In an additional aspect the heterodimeric antibody comprises a first monomer comprising a heavy chain comprising a first Fc domain and a single chain Fv region (scFv) that binds a first antigen, wherein the scFv comprises a charged scFv linker. The heterodimeric antibody further comprises a second monomer comprising a first heavy chain comprising a second Fc domain and a first variable heavy chain and a first light chain. | 12-11-2014 |
20140377270 | OPTIMIZED ANTIBODY VARIABLE REGIONS - The present invention is directed to optimized anti-CD3 variable sequences for use in a variety of bispecific formats, including those that utilize scFv components. The invention further relates to nucleic acids encoding for the polypeptide, to vectors comprising the same and to host cells comprising the vector. In another aspect, the invention provides for a pharmaceutical composition comprising the mentioned polypeptide and medical uses of the polypeptide. | 12-25-2014 |
Patent application number | Description | Published |
20140294759 | TARGETING REGULATORY T CELLS WITH HETERODIMERIC PROTEINS - The present invention relates to methods and compositions for modulating T cells. The modulation includes suppressing or inducing regulatory T cells or cytotoxic T cells. | 10-02-2014 |
20140294836 | TARGETING REGULATORY T CELLS WITH HETERODIMERIC PROTEINS - The present invention provides methods and compositions comprising a heterodimeric antibody comprising a first monomer comprising a first variant heavy chain constant region and an anti-CD4 binding moiety. The heterodimeric antibody also comprises a second monomer comprising: a second variant heavy chain constant region and an anti-CD25 binding moiety. In some cases, the pIs of the first and second variant heavy chain constant regions are at least 0.5 logs apart. | 10-02-2014 |
20140356381 | METHODS OF PURIFYING HETERODIMERIC PROTEINS USING IMMUNOGLOBULIN CLASS SWITCHING - The present invention describes novel immunoglobulin compositions that co-engage at least two antigens, e.g. a first and second antigen, or, as outlined herein, three or four antigens can be bound, in some of the scaffold formats described herein. First and second antigens of the invention are herein referred to as antigen-1 and antigen-2 respectively (or antigen-3 and antigen-4, if applicable. As outlined herein, a number of different formats can be used, with some scaffolds relying combinations of monovalent and bivalent bindings. | 12-04-2014 |