Bernards
Charles Lawrence Bernards, Lake Oswego, OR US
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20130015833 | AUTOMATIC POWER CONVERTER BYPASSAANM George; Mark StevenAACI WilsonvilleAAST ORAACO USAAGP George; Mark Steven Wilsonville OR USAANM Bernards; Charles LawrenceAACI Lake OswegoAAST ORAACO USAAGP Bernards; Charles Lawrence Lake Oswego OR US - A power converter includes a bypass circuit connected in parallel with a power stage of the power converter. The bypass circuit provides a lower loss current path in parallel with the power stage when an input voltage of the power converter exceeds a predetermined threshold. The power converter may be a boost power converter used in a vehicle to provide power from a main power bus of the vehicle to a subsystem of the vehicle such as an anti-lock brake system. | 01-17-2013 |
20130016448 | TRANSIENT VOLTAGE BLOCKING FOR POWER CONVERTERAANM George; Mark StevenAACI WilsonvilleAAST ORAACO USAAGP George; Mark Steven Wilsonville OR USAANM Bernards; Charles LawrenceAACI Lake OswegoAAST ORAACO USAAGP Bernards; Charles Lawrence Lake Oswego OR US - A power converter includes a transient voltage protection circuit connected between an input of the power converter and a power stage of the power converter. The transient voltage protection circuit provides a low resistance connection from the input of the power converter to the power stage of the power converter when the input voltage is less than a predetermined threshold, but blocks the input voltage from the power stage when the input voltage is equal to or greater than the predetermined threshold voltage. The power converter may be a boost power converter used in a vehicle to provide power from a main power bus of the vehicle to a subsystem of the vehicle such as an anti-lock brake system. | 01-17-2013 |
Christopher M Bernards, Seattle, WA US
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20110190243 | DIAGNOSIS AND TREATMENT OF BACK PAIN - The present invention relates to methods of diagnosing and/or treating lower back pain (LBP). In one embodiment, the invention relates to a system for diagnosis of a form of lower back pain in an individual, using a means to identify a type and/or a concentration of one or more inflammatory mediators in the epidural space of the individual. In another embodiment, the invention relates to a system for diagnosis of a form of lower back pain in an individual by identifying a type and/or concentration of one or more inflammatory mediators in the epidural space of the individual, and rendering a diagnosis of the form of lower back pain in the individual based on the presence, absence and/or combination of presences and/or absences of one or more inflammatory mediators in the epidural space of the individual | 08-04-2011 |
Daniel Bernards, Lindlar DE
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20090127185 | FILTER ELEMENT - The invention relates to a filter element for filtering fluid for a motor or gearing, comprising a first filter medium which is arranged in a cylindrical way, with the fluid impinging in a perpendicular way on the circumferential surface of the first medium for filtering in an associated filter apparatus, then penetrating and passing through the same. The filter element comprises a second filter medium with a filter density differing from the first filter medium, the first filter medium and the second filter medium being stacked upon each other as filter layers and being jointly wound in a spiral manner. A desired purity of the fluid can thus be achieved more quickly than in filter elements which exclusively allow a radial passage of the fluid through the filter elements. The spiral configuration also achieves a higher dirt absorption capacity. | 05-21-2009 |
20110259838 | SYSTEM FOR ENGINE OIL STORAGE AND FILTRATION IN AN INTERNAL COMBUSTION ENGINE, AND METHOD FOR ENGINE OIL CIRCULATION AND FILTRATION IN AN INTERNAL COMBUSTION ENGINE - The invention relates to a system for engine oil storage and filtration in an internal combustion engine, comprising at least one oil storage device as part of an engine oil circuit, at least one filtration device, and at least one oil delivery pump, wherein the system is characterized in that the filtration device is connected upstream of the oil delivery pump in relation to the delivery direction of the oil, with only suction filtration being provided. | 10-27-2011 |
Daniel A. Bernards, San Francisco, CA US
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20140170204 | Multilayer Thin Film Drug Delivery Device and Methods of Making and Using the Same - Multilayer thin film devices that include a bioactive agent for elution to the surrounding tissue upon administration to a subject are provided. The multilayer thin film devices are useful as medical devices, such as ocular devices. Also provided are methods and kits for localized delivery of a bioactive agent to a tissue of a subject, and methods of preparing the subject devices. The multilayer thin film medical device includes a first layer, a bioactive agent and a second layer. The first and the second layers may be porous or non-porous. The devices have a furled structure, suitable for administration to a subject. | 06-19-2014 |
Daniel A. Bernards, Ithaca, NY US
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20100117518 | CASCADED LIGHT EMITTING DEVICES BASED ON MIXED CONDUCTOR ELECTROLUMINESCENCE - A cascaded light emitting device. The cascaded light emitting device includes: a base electrode formed of a base electrode material and electrically coupled to a base voltage lead; a top electrode layer formed of a top electrode material and electrically coupled to a top voltage lead; a number of electroluminescent layers arranged between and electrically coupled to the base electrode and top electrode layer; and at least one middle electrode layer formed of a middle electrode material. Each of the middle electrodes is coupled between two juxtaposed electroluminescent layers. The electroluminescent layers include a mixed conductor that luminesces with a peak wavelength. | 05-13-2010 |
Joerg Bernards, Katzenelnbogen DE
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20150059714 | Method of Operating an Internal Combustion Engine with a Turbocharger - The present disclosure relates to a method for operating an internal combustion engine for a motor vehicle, in particular a passenger car having a turbocharger with a compressor and a turbine. The method includes determining a change quantity of a gas flow quantity of a gas flow through the internal combustion engine and regulating the compressor based on this change quantity. | 03-05-2015 |
Jorg Bernards, Katzenelnbogen DE
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20090276137 | METHOD TO INCLUDE FAST TORQUE ACTUATORS IN THE DRIVER PEDAL SCALING FOR CONVENTIONAL POWERTRAINS - An engine control system comprises a pedal torque determination module, a driver interpretation module, and an actuation module. The pedal torque determination module determines a zero pedal torque based on a desired engine torque at a zero accelerator pedal position and a minimum torque limit for an engine system. The driver interpretation module determines a driver pedal torque based on the zero pedal torque and an accelerator pedal position. The actuation module controls at least one of a throttle area, spark timing, and a fuel command based on the driver pedal torque. | 11-05-2009 |
Rene Bernards, Abcoude NL
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20090157326 | Diagnosis and prognosis of breast cancer patients - The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein. | 06-18-2009 |
20100297624 | Involvement of Lipid Kinase, and Signal Transduction Pathway Comprising Said Lipid Kinase, in Resistance to HER2-Targeting Therapy - The invention is related to a method for determining whether an individual suffering from cancer is at risk of exhibiting or acquiring a reduced response towards HER2-targeting therapy. In one aspect, the invention utilizes the activity of a signal transduction pathway modulated by a lipid kinase for determining said risk. | 11-25-2010 |
20110301048 | DIAGNOSIS AND PROGNOSIS OF BREAST CANCER PATIENTS - The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein. | 12-08-2011 |
20130116145 | DIAGNOSIS AND PROGNOSIS OF BREAST CANCER PATIENTS - The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein. | 05-09-2013 |
20130302321 | Methods and Means for Typing a Sample Comprising Cancer Cells Based on Oncogenic Signal Transduction Pathways - The invention is related to a method of determining whether an individual suffering from cancer is likely to respond to anti-EGFR and/or EGFR pathway therapy. In one aspect, the invention utilizes the expression level of a set of genes for determining said response. In a further aspect, the invention relates to a method of assigning treatment to an individual suffering from cancer. | 11-14-2013 |
René Bernards, Amsterdam NL
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20130123327 | COMBINED USE OF PRAME INHIBITORS AND HDAC INHIBITORS - The invention relates to the cancer antigen PRAME (PReferentially expressed Antigen in MElanoma) and its use in a method of treatment of a tumour which comprises administering to a subject in need of treatment an effective amount of an inhibitor of PRAME, in combination with a second agent selected from the group of an inhibitor of HDAC (an HDACi) and a retinoid. | 05-16-2013 |
20140287931 | METHODS AND COMPOSITIONS FOR PREDICTING RESISTANCE TO ANTICANCER TREATMENT - The instant application provides methods and related compositions pertaining to the identification of resistance to anticancer treatment in. a patient. In a particular embodiment, the invention provides biomarkers for the identification of resistance to anticancer treatment in a breast cancer patient, wherein a reduced expression of a MEDIATOR and/or SWI/SNF complex gene in the breast cancer cells of the patient indicates that the breast cancer cells in the patient may be successfully treated with a PI3K and/or mTOR inhibitor. | 09-25-2014 |
20140296248 | METHODS AND COMPOSITIONS FOR PREDICTING RESISTANCE TO ANTICANCER TREATMENT - The instant application provides methods and related compositions pertaining to the identification of resistance to anticancer treatment in a patient. In a particular embodiment, the invention provides biomarkers for the identification of resistance to anticancer treatment in a lung cancer patient, wherein a reduced expression of a MEDIATOR and/or SW1/SNF complex gene in the lung cancer cells of the patient indicates that the lung cancer cells in the patient may be resistant to treatment with a receptor tyrosine kinase inhibitor, such as gefitinib and/or erlotinib. In some embodiments, the invention relates to methods and related compositions for predicting resistance to anticancer treatment by detecting the expression levels of one or more TGF-beta pathway nucleic acids and/or proteins. | 10-02-2014 |
René Bernards, Amsterdam NL
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20130123327 | COMBINED USE OF PRAME INHIBITORS AND HDAC INHIBITORS - The invention relates to the cancer antigen PRAME (PReferentially expressed Antigen in MElanoma) and its use in a method of treatment of a tumour which comprises administering to a subject in need of treatment an effective amount of an inhibitor of PRAME, in combination with a second agent selected from the group of an inhibitor of HDAC (an HDACi) and a retinoid. | 05-16-2013 |
Roger Bernards, South Haven, MN US
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20140299480 | Copper Plating Solutions and Method of Making and Using Such Solutions - The present technology generally relates to copper plating solutions. Specifically, the present technology includes a copper plating solution comprising a source of copper ions and a conductivity salt wherein the copper plating solution has a pH between 1.7 and 3.5 as is essentially free of chloride ions. The present technology also relates to a method of using such copper plating solutions. | 10-09-2014 |
Roger F. Bernards, South Haven, MN US
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20090198006 | Methods And Compositions For Depositing Silver Onto A Metal Surface - The current method and composition relate to depositing silver onto a metal surface using an acid selected from the group consisting of salicylic acid and salicylic acid derivatives; a source of silver ions; and an additive selected from the group consisting of polyethylene glycol, a block copolymer of polyethylene glycol and | 08-06-2009 |
20100006799 | Method and Composition for Selectively Stripping Nickel from a Substrate - A method of stripping nickel from a printed wiring board comprises providing a printed wiring board with a nickel deposit on a surface and contacting the nickel deposit with phosphate ions and an oxidizer. An aqueous solution comprises ammonium ions, phosphate ions and an oxidizing agent present in amounts effective to strip nickel. An aqueous solution comprises about 1% to about 10% by weight hydrogen peroxide and about 5% to about 30% by weight of an ammonium phosphate. A method of pre-treating a copper substrate comprises providing a printed wiring board having a copper substrate and contacting the copper substrate with phosphate ions, and an oxidizer. A method of neutralizing permanganate on a printed wiring board comprises providing a printed wiring board with a permanganate residue on the printed wiring board and contacting the permanganate residue with phosphate ions, and an oxidizer. | 01-14-2010 |
20110039019 | Solution and Process for Improving the Solderability of a Metal Surface - The invention is directed to a solution and process for improving the solderability of a metal surface. In one embodiment, the invention is a silver deposit solution comprising an acid, a source of silver ions, and an additive selected from among pyrroles, triazoles, and tetrazoles, as well as derivatives and mixtures of those components. In another embodiment, the silver deposit solution also includes a 6-membered heterocyclic ring compound, wherein three members of the 6-membered heterocyclic ring are nitrogen atoms. Still another embodiment is a process for improving the solderability of a metal surface which involves applying a silver deposit solution as previously described to a metal surface. | 02-17-2011 |
Thomas Nicolaas Maria Bernards, Eindhoven NL
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20100155709 | ENCAPSULATION FOR AN ELECTRONIC THIN FILM DEVICE - The present invention relates to an encapsulation for an electronic thin film device, comprising a first barrier layer ( | 06-24-2010 |
20130037787 | ORGANIC LIGHT EMITTING DEVICE - The invention relates to an organic light-emitting device (OLED) comprising at least: a first electrode ( | 02-14-2013 |