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Bernard, CA
Charles Bernard, Moorpark, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090137837 | METHODS OF SYNTHESIZING CINACALCET AND SALTS THEREOF - Methods of preparing cinacalcet, cinacalcet derivatives, and salts thereof is disclosed herein. Also disclosed herein are polymorphs of cinacalcet, compositions of cinacalcet, and methods of treating a subject by administering cinacalcet, wherein cinacalcet is prepared by the disclosed methods. | 05-28-2009 |
| 20100280255 | PROCESS FOR MAKING SUBSTITUTED 2-AMINO-THIAZOLONES - The present invention relates to methods of making compounds that inhibit 11-hydroxysteroid dehydrogenase type 1 enzyme (11-HSD1). One method comprises (a) contacting a compound of formula (II) sequentially with a chiral base in the presence of an amine, and an alkylating agent R3-LG, (b) contacting the product of (a) with an acid to form a salt, and (c) reacting the salt with a base to form the compound of formula (I), wherein Z, R1, R2, and R3 are defined herein. | 11-04-2010 |
| 20110160463 | PROCESS FOR MAKING SUBSTITUTED 2-AMINO-THIAZOLONES - The present invention relates to methods of making compounds that inhibit 11-β-hydroxysteroid dehydrogenase type 1 enzyme (11-β HSD1). One method comprises (a) contacting a compound of formula (II) with a chiral base, deprotonating agent, and an alkylating agent R | 06-30-2011 |
| 20110281954 | METHODS OF SYNTHESIZING CINACALCET AND SALTS THEREOF - Methods of preparing cinacalcet, cinacalcet derivatives, and salts thereof is disclosed herein. Also disclosed herein are polymorphs of cinacalcet, compositions of cinacalcet, and methods of treating a subject by administering cinacalcet, wherein cinacalcet is prepared by the disclosed methods. | 11-17-2011 |
Christophe G. Bernard, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090248883 | APPARATUS AND METHODS FOR MANAGING WIDGETS IN A WIRELESS COMMUNICATION ENVIRONMENT - Apparatus and methods relating to mobile widgets. In particular, apparatus and methods for integrating network services and/or network resources with widget capabilities, managing mobile widgets, providing portability to mobile widgets, and generating content with respect to a mobile widget. In one aspect, a method for integration of network services and/or resources with widget capabilities is provided. The method may include providing for an interface between a widget management component and at least one of a network resource or a network service. The method may also include accessing, at the widget management component via the interface, at least one of a network resource or network service. Further, the method may include integrating the network resource or the network service with a widget functionality. | 10-01-2009 |
| 20090248996 | APPARATUS AND METHODS FOR WIDGET-RELATED MEMORY MANAGEMENT - Apparatus and methods for changing operational modes of a widget and changing content feed to a widget based on operational mode changes and/or memory availability on the wireless device are provided. Apparatus and methods for managing the runtime memory usage of mobile widgets on a wireless device by changing widget states based on widget usage data are also provided. | 10-01-2009 |
| 20090249321 | APPARATUS AND METHODS FOR WIDGET UPDATE SCHEDULING - Methods and apparatus for scheduling a content update of a mobile widget are provided. The method may include receiving a widget update consideration. The method may also include generating a content update schedule for a mobile widget based on the update consideration. Further, the method may include storing the generated content update schedule for use in updating a content of the mobile widget. | 10-01-2009 |
| 20090271778 | APPARATUS AND METHODS FOR TRANSPORT OPTIMIZATION FOR WIDGET CONTENT DELIVERY - Apparatus and methods for transport optimization for widget content delivery includes obtaining updated content corresponding to a mobile widget having a plurality of informational hierarchical depths, and obtaining user navigation pattern historical data corresponding to the mobile widget, wherein the user navigation pattern historical data corresponds to the plurality of informational hierarchical depths. The aspects also include obtaining a first informational hierarchical depth range for inclusion in a first content update message for delivery to a device, wherein the first informational hierarchical depth range is based on the user navigation pattern historical data. Further, the aspects include generating a content update message with a first portion of the updated content corresponding to the first informational hierarchical depth range. Optionally, the aspects further include reducing a size of the first portion of the updated content in the first content update message, thereby defining a first compressed portion of the updated content. | 10-29-2009 |
Chuck Bernard, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110173345 | Method and system for HTTP-based stream delivery - A method of delivering a live stream is implemented within a content delivery network (CDN) and includes the high level functions of recording the stream using a recording tier, and playing the stream using a player tier. The step of recording the stream includes a set of sub-steps that begins when the stream is received at a CDN entry point in a source format. The stream is then converted into an intermediate format (IF), which is an internal format for delivering the stream within the CDN and comprises a stream manifest, a set of one or more fragment indexes (FI), and a set of IF fragments. The player process begins when a requesting client is associated with a CDN HTTP proxy. In response to receipt at the HTTP proxy of a request for the stream or a portion thereof, the HTTP proxy retrieves (either from the archive or the data store) the stream manifest and at least one fragment index. Using the fragment index, the IF fragments are retrieved to the HTTP proxy, converted to a target format, and then served in response to the client request. The source format may be the same or different from the target format. Preferably, all fragments are accessed, cached and served by the HTTP proxy via HTTP. In another embodiment, a method of delivering a stream on-demand (VOD) uses a translation tier (in lieu of the recording tier) to manage the creation and/or handling of the IF components. | 07-14-2011 |
| 20110296048 | Method and system for stream handling using an intermediate format - A method of delivering a live stream is implemented within a content delivery network (CDN) and includes the high level functions of recording the stream using a recording tier, and playing the stream using a player tier. The step of recording the stream includes a set of sub-steps that begins when the stream is received at a CDN entry point in a source format. The stream is then converted into an intermediate format (IF), which is an internal format for delivering the stream within the CDN and comprises a stream manifest, a set of one or more fragment indexes (FI), and a set of IF fragments. The player process begins when a requesting client is associated with a CDN HTTP proxy. In response to receipt at the HTTP proxy of a request for the stream or a portion thereof, the HTTP proxy retrieves (either from the archive or the data store) the stream manifest and at least one fragment index. Using the fragment index, the IF fragments are retrieved to the HTTP proxy, converted to a target format, and then served in response to the client request. The source format may be the same or different from the target format. Preferably, all fragments are accessed, cached and served by the HTTP proxy via HTTP. | 12-01-2011 |
Francis S. Bernard, Brentwood, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120036388 | SYSTEM AND METHOD FOR SYNCHRONIZING MULTIPLE MEDIA DEVICES - Multiple media devices are synchronized in a multi-media system having a computer system, a plurality of media devices, and a display system. Each media device to be synchronized receives a front-end synchronization signal that periodically increments a front-end counter. The front-end counter represents an unadjusted system time (UST). The media device obtains a frame of data to be displayed from a computer system. The media device also receives a back-end synchronization signal that periodically increments a back-end counter each time a frame of data is to he displayed. The back-end counter represents a media stream count (MSC). UST and MSC data are periodically transmitted to the computer system for analysis and use by a synchronization algorithm. Specifically, UST is transmitted to the computer system each time a frame of data is obtained, and a UST/MSC pair is transmitted to the computer system each time a frame of data is displayed. The computer system executes a synchronization algorithm that uses the transmitted UST and UST/MSC pair to maintain the media devices in a synchronized state. | 02-09-2012 |
Frank Bernard, American Canyon, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110258837 | FLEXIBLE MANUFACTURING SYSTEM - A flexible, multi-product, multi-technology, expandable facility for manufacturing products, such as biologicals, pharmaceuticals, or chemicals, and manufacturing processes using elements of such a facility. | 10-27-2011 |
James Bernard, Thousand Oaks, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110281653 | INTERACTIVE BROADCAST SPORTS GAMING - A method of interactive gaming includes identifying a broadcast event, generating interactive questions for the broadcast event based upon a subject of the broadcast event, organizing the generated questions based on a structure of the broadcast event, and providing the organized questions to a user during a broadcast of the broadcast event through an interactive gaming interface based on the structure of the broadcast event. | 11-17-2011 |
Joffre Bernard, Santa Clara, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090163018 | Method to prevent alloy formation when forming layered metal oxides by metal oxidation - The present method of fabricating a resistive memory device includes the steps of providing a first electrode, oxidizing a portion of the first electrode with an oxidizing agent, providing a metal body on the oxidized portion of the first electrode, oxidizing the entire metal body with an oxidizing agent, and providing a second electrode on the oxidized metal body. | 06-25-2009 |
Joffre F. Bernard, Santa Clara, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080265240 | Memory device with improved performance - The present resistive memory device includes first and second electrodes. An active layer is situated between the first and second electrodes. The active layer with advantage has a thermal conductivity of 0.02 W/Kcm or less, and is surrounded by a body in contact with the layer, the body having a thermal conductivity of 0.01 W/Kcm or less. | 10-30-2008 |
Mark Bernard, Walnut Creek, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110135635 | ANTI-ALPHA2 INTEGRIN ANTIBODIES AND THEIR USES - The invention relates to anti-α2 integrin antibodies and their uses. Humanized antibodies are disclosed that bind to the I domain of α2 integrin and inhibit the interaction of α2β1 integrin with collagen. Also disclosed are therapeutic uses of anti-α2 integrin antibodies in treating α2β1-mediated disorders, including anti-α2 integrin antibodies that bind to α2 integrin without activating platelets. | 06-09-2011 |
Peter A. Bernard, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080208967 | Method and System for Improved Internet Color - The present invention provides a technique for providing color corrected images to a user over a network. In particular, the present invention allows multiple image providers to provide color corrected images to a user when the user's computer and its associated devices are not calibrated and/or characterized, or the calibration and/or characterization data is not available over the network to the image providers. This abstract is provided for the sole purpose of complying with the rules requiring an abstract to allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure contained herein. This abstract is submitted with the express understanding that it will not be used to interpret or to limit the scope or the meaning of the claims. | 08-28-2008 |
| 20110115809 | Method and System for Improved Internet Color - The present invention provides a technique for providing color corrected images to a user over a network. In particular, the present invention allows multiple image providers to provide color corrected images to a user when the user's computer and its associated devices are not calibrated and/or characterized, or the calibration and/or characterization data is not available over the network to the image providers. This abstract is provided for the sole purpose of complying with the rules requiring an abstract to allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure contained herein. This abstract is submitted with the express understanding that it will not be used to interpret or to limit the scope or the meaning of the claims. | 05-19-2011 |
Robert M. Bernard, Rancho Santa Fe, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100016828 | Drug Delivery System and Method - A method for delivering a therapeutic agent to a predetermined location in a host is disclosed, wherein a liposome-encapsulated therapeutic agent is administered to the host, and an electrical field which encompasses a predetermined region within the host is established, such that as the liposome-encapsulated agent is exposed to the electrical field the release of the agent from the liposome to the predetermined region is enhanced. | 01-21-2010 |
| 20110288467 | METHOD AND APPARATUS FOR DELIVERY OF THERAPEUTIC AGENTS - Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a patient. The invention includes controlled administration of the therapeutic agent through an orifice to the patient, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes. | 11-24-2011 |
Victor Bernard, San Jose, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090100068 | Digital content Management system - Disclosed herein is a method and device for managing, organizing, sharing, discovering, and preserving digital media content. A user may view the digital content, metadata, and information indicating the state of the digital content using the display means provided for the digital content management device. A plurality of communication interfaces is provided on the digital content management device to interface with a plurality of local and remote devices. The digital content management device may be used to access and track the digital content on the plurality of local and remote devices. Further, a network interface is provided on the digital content management device to access a plurality of public and private networks and their associated digital content storage devices. In order to enable a user to edit, organize, share, discover, preserve, and manage the digital content, a user interface is provided for the digital content management device. | 04-16-2009 |