Patent application number | Description | Published |
20100124785 | WILD-CARD-MODIFICATION TECHNIQUE FOR PEPTIDE IDENTIFICATION - Embodiments of a computer system, a method, and a computer-program product (e.g., software) for analyzing tandem-mass-spectrometry data are described. Using this analysis technique, unanticipated chemical modifications to peptides associated with proteins can be identified. In particular, a modification called a wild-card modification is used to identify the most likely chemical modifications in the peptides. A wild-card modification allows the addition of any mass, typically any integer atomic mass within a range, to any one amino acid residue within a candidate peptide. | 05-20-2010 |
20110093205 | PROTEOMICS PREVIEWER - A technique for analyzing proteomics data (such as tandem mass-spectrometry data) corresponding to peptides in a sample is described. In a high-speed, low-sensitivity first pass of this analysis technique, analysis parameters, such as the presence of one or more potential modifications to the one or more peptides, are determined using a representative subset of a database of known proteins. For example, a given potential modification in the one or more potential modifications may be determined by comparing matches between measured mass-spectrometry spectra and generated theoretical mass-spectrometry spectra without the given potential modification to matches between the measured mass-spectrometry spectra and generated theoretical mass-spectrometry spectra with the given potential modification. Then, in a lower-speed, higher-sensitivity second pass of the analysis technique, one or more peptides and/or proteins in the proteomics data are identified using the database of known proteins and the determined analysis parameters. | 04-21-2011 |
20110311145 | SYSTEM AND METHOD FOR CLEAN DOCUMENT RECONSTRUCTION FROM ANNOTATED DOCUMENT IMAGES - A computer-implemented method and system for reconstructing a clean document from annotated document images and/or extracting annotations therefrom are provided. The method includes receiving a set of at least two annotated document images into computer memory, selecting a representative image from the set of annotated document images, performing a global alignment on each of the set of annotated document images with respect to the selected representative image, and forming a consensus document image based at least on the aligned annotated document images. A clean document based at least on the consensus document image is then formed which can be used for extracting the annotations. | 12-22-2011 |
20130144540 | CONSTRAINED DE NOVO SEQUENCING OF PEPTIDES - A peptide sequencing system derives a peptide sequence from a mass spectrum. The system can receive a description for a peptide sequence constraint, such that the constraint indicates a symbol pattern that is to be present in a peptide sequence derived from the mass spectrum. Then, the system generates a peptide sequence based on the mass spectrum and the constraint, such that the peptide sequence matches the constraint and has a mass that matches the total mass of the peptide as determined from the mass spectrum. | 06-06-2013 |
20130153771 | TRAFFIC MONITORING BASED ON NON-IMAGING DETECTION - Traffic monitors based on non-imaging radiation detectors are described. A traffic monitor includes a non-imaging radiation detector that senses spatially patterned radiation emanating from objects moving in a traffic pattern. The detector generates a time varying output signal based on the sensed radiation. Signal processing circuitry is used to analyze the time varying output signal using time domain analysis to provide the traffic information. | 06-20-2013 |
20130159352 | GENERATING SKETCHES SENSITIVE TO HIGH-OVERLAP ESTIMATION - A versioning system determines an amount by which a first collection and a second collection of data objects overlap. The system divides the first collection of data objects into m possibly overlapping groups of average size s and computes one combined hash result for each group. The system then constructs a first sketch vector with n elements based on the combined hash results. A respective element of the first sketch vector is selected, using a selection function, from the combined hash results that are computed with the hash function corresponding to the element's index. Next, the system receives a second sketch vector for the second collection of data objects, and determines a sketch-vector overlap between the first and second sketch vectors. The system then computes a data-object overlap between the first and second collections of data objects based on the sketch-vector overlap. | 06-20-2013 |
20140192359 | ANALYZERS WITH TIME VARIATION BASED ON COLOR-CODED SPATIAL MODULATION - A filter arrangement can transmit and/or reflect light emanating from a moving object so that the emanating light has time variation, and the time variation can include information about the object, such as its type. For example, emanating light from segments of a path can be transmitted/reflected through positions of a filter assembly, and the transmission functions of the positions can be sufficiently different that time variation occurs in the emanating light between segments. Or emanating light from a segment can be transmitted/reflected through a filter component in which simpler transmission functions are superimposed, so that time variation occurs in the emanating light in accordance with superposition of two simpler non-uniform transmission functions. Many filter arrangements could be used, e.g. the filter component could include the filter assembly, which can have one of the simpler non-uniform transmission functions. Time-varying waveforms from sensing results can be compared to obtain spectral differences. The filter arrangement, in a practical commercial embodiment, can be manufactured to be disposable, and used in a point-of-care device for use practically anywhere, at low cost, and can also be implemented in an in-line monitoring system. | 07-10-2014 |
20150161398 | METHOD AND APPARATUS FOR PRIVACY AND TRUST ENHANCING SHARING OF DATA FOR COLLABORATIVE ANALYTICS - One embodiment of the present invention provides a system for privacy-preserving sharing of data for secure collaboration. During operation, the system obtains a first set of data describing network events associated with one or more network addresses. Next, the system negotiates with a potential partner to determine a metric for deciding whether to share data. The potential partner is associated with a second set of data describing network events. The system then computes a value for the metric in a privacy-preserving way, based on the first set of data and the second set of data. Subsequently, the system determines whether the metric value exceeds a predetermined threshold, and, responsive to determining that the metric value exceeds the predetermined threshold, the system shares the first set of data with the potential partner, while controlling how the data should be shared to optimize benefits and risks of collaboration. | 06-11-2015 |
20150233703 | SPATIAL MODULATION OF LIGHT TO DETERMINE OBJECT LENGTH - Spatially modulated light emanating from an object moving along a flow path is used to determine various object characteristics including object length along the flow direction. Light emanating from at least one object moving along in a flow path along a flow direction of a spatial filter is sensed. The intensity of the sensed light is time modulated according to features of the spatial filter. A time varying electrical signal is generated which includes a plurality of pulses in response to the sensed light. Pulse widths of at least some of the pulses are measured at a fraction of a local extremum of the pulses. The length of the object along the flow direction is determined based on the measured pulse widths. | 08-20-2015 |
20150233704 | SPATIAL MODULATION OF LIGHT TO DETERMINE DIMENSIONAL CHARACTERISTICS OF OBJECTS IN A FLOW PATH - A device includes a spatial filter arranged in a Cartesian coordinate system having orthogonal x, y, and z axes. The spatial filter has mask features that are more light transmissive and mask features that are less light transmissive. The mask features are arranged along the x-axis in the flow direction of a flow path. A detector is positioned to detect light emanating from at least one object in the flow path, the object having a width along the y-axis, a thickness along the z-axis, and a length along the x-axis. Light emanating from the object is time modulated according to the mask features as the object moves along the flow path. The detector is configured to generate a time-varying electrical signal in response to the detected light that includes information about the width or thickness of the object. | 08-20-2015 |
20150276387 | SPATIAL MODULATION OF LIGHT TO DETERMINE OBJECT POSITION - Approaches for determining object position in a flow path are disclosed. A system includes a spatial filter having a length disposed along a longitudinal axis of the flow path and a width along a lateral axis of the flow path. The spatial filter has mask features configured to modulate light. Light emanating from objects moving along the flow path is detected. The detected light has a component along a detection axis that makes a non-zero angle with respect to the longitudinal and lateral axes. An electrical output signal that includes information about the trajectory depth of the object is generated in response to the detected light. | 10-01-2015 |
20150276486 | DETERMINATION OF COLOR CHARACTERISTICS OF OBJECTS USING SPATIALLY MODULATED LIGHT - A system is configured to determine a color distribution of an object moving along a flow direction relative to a spatial filter. The light emanating from the object is time modulated according to the mask features of the spatial filter. First and second detectors are arranged to sense the modulated light. The first detector senses light having a first wavelength spectrum and generates a first electrical output signal in response to the sensed light. The second detector light senses light having a second wavelength spectrum and generates a second electrical output signal in response to the sensed light. Signals from the first and second detectors include information about color distribution of the object. | 10-01-2015 |
20150286824 | METHODS FOR SELECTION OF COLLABORATORS FOR ONLINE THREAT MITIGATION - One embodiment of the present invention provides a system for stable selection of collaborating partners for exchanging security data. During operation, the system receives vectors of collaboration values from a plurality of entities. A collaboration value is a measure of an expected benefit of collaborating with a respective entity. The system sorts each of the vectors by the collaboration values of the respective vector. The system then determines matching entities given a number of partners wanted by each organization in N. The system may add matching entities to lists of collaborating partners given the number of partners wanted by each organization in N. Subsequently, the system sends the lists of collaborating partners to facilitate exchanging security data with partners in the list of collaborating partners. | 10-08-2015 |
20150286825 | METHODS FOR CENTRALIZED PRIVACY-PRESERVING COLLABORATIVE THREAT MITIGATION - One embodiment of the present invention provides a system to facilitate collaboration for mitigating network threats. During operation, the system receives encrypted data sets from a plurality of entities. The data sets including data describing threats to network security. The system performs privacy-preserving operations on the encrypted data sets, such as private set intersection. The system then computes one or more metrics based on results of the private set intersection computations. The system may generate a similarity matrix based on the one or more metrics, and returns one or more similarity values from the similarity matrix to one or more entities of the plurality of entities. | 10-08-2015 |