Bercovich

A. Bercovich, Ciudad De Buenos Aires AR

Patent application number	Description	Published
20090187999	Process for Producing Exogenous Protein in the Milk of Transgenic Mammals and a Process For Purifying Proteins Therefrom - The invention relates to a non-human transgenic mammal that is useful for the production of a protein of interest that may be toxic to the mammal. The mammal is characterized by the fact that it is transgenic for the production in its milk of an inactive form of the protein of interest, preferably recombinant human insulin. It is not possible to produce recombinant human insulin in transgenic mammals since this molecule has a certain degree of biological activity in the mammals and could be toxic to the mammal. Thus, the invention involves cloning a genetic construct comprising a sequence encoding a modified human insulin precursor under the control of a beta casein promoter in an expression vector. It also involves transfecting the expression plasmid into fetal bovine somatic cells, such as fibroblasts, and enucleating bovine oocytes by nuclear transfer to generate transgenic embryos. The invention gives rise to transgenic bovine that will be able to produce a modified human insulin precursor in their mammary glands. Afterwards, the milk of these transgenic mammals can be collected, the modified human insulin precursor can be converted in vitro into recombinant human insulin, and the recombinant human insulin can be purified to homogeneity as a pure biopharmaceutical product.	07-23-2009

Patent application number	Description	Published
20110075574	PATH PROTECTION BY SHARING CONTINUITY CHECK MESSAGES - A method for managing protection of a plurality of defined paths in a communication system including listing the defined paths, each item in the list including a defined path identifier, a defined path ingress node, a defined path egress node, and a defined path protection period, wherein some of the defined paths share an ingress node and an egress node, managing a sending of Continuity Check Messages (CCMs) along at least some of the defined paths, such that a CCM is sent every protection period, and for at least a plurality of the defined paths which share an ingress node and an egress node, managing a sharing of the protection of the plurality of the defined paths, the sharing including sending one set of CCMs, shared by the plurality of the defined paths, at a frequency based, at least in part, on a shortest one of the protection periods of the plurality of the defined paths. A method for protecting a plurality of paths which share at least one leg in a communication network, including sharing, between the paths, Continuity Check Messages (CCMs) for at least the shared leg. Related apparatus and methods are also described.	03-31-2011

Patent application number	Description	Published
20100164817	Applications for Low Profile Two Way Satellite Antenna System - Antenna assemblies and associated satellite tracking systems that may include a low profile two-way antenna arrangement, tracking systems, and applications thereof. Applications for the system include military, civilian, and domestic emergency response applications. The antenna arrangements may be configured to form a spatial element array able to track a satellite in an elevation plane by electronically dynamically targeting the antenna arrangement and/or mechanically dynamically rotating the antenna arrangements about transverse axes giving rise to generation of respective elevation angles and dynamically changing the respective distances between the axes whilst maintaining a predefined relationship between said distances and the respective elevation angles. The system provides dynamic tracking of satellite signals and can be used for satellite communications on moving vehicles in military and civilian applications.	07-01-2010