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Berardi

Alain Berardi, Marseille FR

Patent application numberDescriptionPublished
20100234543PROCESS FOR POLYMERISING ETHYLENE - The present invention relates to a process for polymerisation of ethylene, in particular a process which comprises using a catalyst system comprising comprising a catalyst system comprising: i) a solid catalyst comprising Ti, Mg and halogen, ii) a first activator which is at least one trialkylaluminium compound of the formula AIR09-16-2010

Francesco Berardi, Noicattaro Ba IT

Patent application numberDescriptionPublished
200900934931-PHENYLALCOXY-2-BETA-PHENYLETHYL DERIVATIVES AS P-GLYCOPROTEIN (P-GP) INHIBITORS USEFUL IN DRUG RESISTANCE EVENTS - The invention relates to a new class of compounds, which are 1-phenylalcoxy-2-β-phenylethyl derivatives, as P-glycoprotein (P-GP) inhibitors. These compounds are useful in drug resistance events. They have been shown able to inhibit in a dose-dependent manner Glycoprotein-P (P-gp) activity in cell lines in which the expression of said glycoprotein is very high, like Caco-2 (human colon cancer) cells and MCF7/Adr (adriamycin-resistant human breast carcinoma) cells. The invention also relates to methods of production and the utilization of such compounds as medicaments useful in the treatment of states linked to the difficulty for some drugs to cross the blood-brain barrier (BBB) and generally within the context of the problems of drug resistance induced by chemotherapy agents.04-09-2009

Francesco Berardi, Bari IT

Patent application numberDescriptionPublished
20090017038Sigma-2 Receptor, Method of Screening of Specific Ligands and Use of the Same in Diagnostic or Therapeutic Methods - The present invention relates to the identification, isolation and characterization of the proteins forming the sigma-2 receptor. The invention further relates to the utilization of said proteins for preparing a screening for the sigma-2 receptor, as well as assay of specific candidate ligands to the use of the ligands for setting up diagnostic assays for tumour tissues and for preparing antitumour drugs. Lastly, the isolated proteins are utilized for producing anti-receptor antibodies, which likewise find employ in the diagnosis and therapeutic treatment of neoplasias.01-15-2009

Giorgio Berardi, Patrica IT

Patent application numberDescriptionPublished
20110245485PROCESS FOR THE SYNTHESIS OF AZACITIDINE AND DECITABINE - Described herein is a process for the synthesis of azacitidine or decitabine, comprising the silylation of azacytosine in the presence of N,O-bis-trimethylsilyl-trifluoroacetamide. Such reaction is performed in an organic solvent, preferably aprotic, even more preferably selected from among dichloromethane, dichloroethane and/or acetonitrile. According to a further aspect of the process, 2 to 3 moles of N,O-bis-trimethylsilyl-trifluoroacetamide are used per mole of azacytosine, preferably from 2.2 to 2.5.10-06-2011

Rogerio Berardi, Sao Paulo BR

Patent application numberDescriptionPublished
20080251227TISSUE MACHINE - An apparatus for producing a fibrous web, in particular a tissue web, with a press zone through which the fibrous web is passed in a lying position between a circulating permeable structured belt and a circulating permeable non-structured supporting belt. A press nip is provided on a Yankee Cylinder through which the fibrous web is passed in the lying position together with the structured belt between the structured belt and the Yankee cylinder, whereby the press zone is limited on the side adjacent the supporting belt by a substantially smooth surface, and whereby the supporting belt is not brought together with the fibrous web and the structured belt until proximate to the press zone.10-16-2008
20080257513APPARATUS AND METHOD FOR TREATING A FIBROUS WEB, IN PARTICULAR FOR PRODUCING A TISSUE PAPER WEB - The present invention provides an apparatus the surface of the web supporting face and/or the material forming the web supporting face are selected with a view to little crêping belt wear caused by operation of the apparatus, in particular with a view to a small coefficient of friction.10-23-2008
20080257514APPARATUS AND METHOD FOR TREATING A FIBROUS WEB, IN PARTICULAR FOR PRODUCING A TISSUE PAPER WEB - Apparatus for treating a fibrous web, in particular for producing a tissue paper web, with at least one crêping nip which is limited on the one side by a crêping belt and on the other side by a web supporting face formed in particular by a mating roll and through which the fibrous web can be passed, whereby a relative speed is provided between the crêping belt and the web supporting face, whereby in order to achieve a good crêping effect with simultaneous little crêping belt wear the material and/or the structure of the web supporting face and the surface of the crêping belt are coordinated with each other with a view to reducing the crêping belt wear caused by operation of the apparatus.10-23-2008
20090205794METHOD FOR THE PRODUCTION OF TISSUE PAPER - A method for the production of a tissue paper web, which is produced from a pulp suspension comprised of fibers, the pulp suspension having a refining degree of less than 21°SR and being of such condition that it is possible to produce from said pulp suspension a laboratory sheet according to TAPPI 205 SP 95 (Rapid Köthen) whose breaking length measured according to TAPPI 220 and TAPPI 494 at least a specific refining degree (RD08-20-2009
20090242158PROCESS AND APPARATUS FOR PRODUCING A TISSUE WEB - An apparatus for producing a fibrous web includes: a circulating permeable structured belt defining a sheet forming zone in which the fibrous web is formed; a circulating unstructured permeable supporting belt; a pressing section through which the fibrous web is led lying between the circulating permeable structured belt and the circulating unstructured permeable supporting belt; a Yankee cylinder having a surface and defining a press nip and a press nip region, wherein the fibrous web is led together with the structured belt through said press nip, the fibrous web in the region of the press nip being transferred from the structured belt to the surface of the Yankee cylinder; at least one doctor which doctors off the surface of the Yankee cylinder continuously; and a coating device which recoats the surface of the Yankee cylinder so that a renewed coating material is always present in the press nip.10-01-2009

Patent applications by Rogerio Berardi, Sao Paulo BR