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| 20110002990 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF - The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. | 01-06-2011 |
| 20110002991 | PHENYLETHANOIC ACID, PHENYLPROPANOIC ACID AND PHENYLPROPENOIC ACID CONJUGATES AND PRODRUGS OF HYDROCODONE, METHOD OF MAKING AND USE THEREOF - The presently described technology provides phenylethanoic acid, phenylpropanoic acid, phenylpropenoic acid, a salt thereof, a derivative thereof or a combination thereof chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs or compositions of hydrocodone which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. | 01-06-2011 |
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| 20090159002 | Gas distribution plate with annular plenum having a sloped ceiling for uniform distribution - A gas distribution plate for a plasma reactor has an annular gas distribution plenum with an array of gas injection holes and a gas injection port at one end of the annular plenum, the plenum being progressively constricted in cross-sectional area along its azimuthal path by a sloping ceiling. | 06-25-2009 |
| 20090159213 | Plasma reactor gas distribution plate having a path splitting manifold immersed within a showerhead - A showerhead of a plasma reactor has an internal plenum comprising a showerhead floor and a plurality of gas injection holes through the floor of the showerhead. A path splitting manifold is immersed inside the plenum and comprises a gas supply inlet, plural gas outlets, and a plurality of channels comprising plural paths of equal lengths between the inlet and respective ones of the plural outlets. | 06-25-2009 |
| 20090162260 | Plasma reactor gas distribution plate with radially distributed path splitting manifold - In a showerhead assembly, a path splitting manifold comprises a gas supply inlet and a planar floor and plural gas outlets extending axially through the floor and azimuthally distributed about the floor. The path splitting manifold further comprises a plurality of channels comprising plural paths between the inlet and respective ones of the plural outlets. A gas distribution showerhead underlies the floor of the manifold and is open to the plural outlets. In certain embodiments, the plural paths are of equal lengths. | 06-25-2009 |
| 20090162262 | Plasma reactor gas distribution plate having path splitting manifold side-by-side with showerhead - A path splitting manifold of a showerhead assembly comprises a gas supply inlet and a side wall and plural gas outlets extending radially through the side wall. The path splitting manifold further comprises a plurality of channels comprising plural paths between the inlet and respective ones of the plural outlets. A showerhead is adjacent the side wall and is open to the plural outlets. In one embodiment, the paths are of equal lengths. | 06-25-2009 |
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| 20090202552 | GENE EXPRESSED IN PROSTATE CANCER AND METHODS OF USE - A new polypeptide is disclosed that is specifically detected in the cells of the prostate, termed Novel Gene Expressed in Prostate (NGEP). Polynucleotides encoding NGEP are also disclosed, as are vectors including these polynucleotides. Host cells transformed with these polynucleotides are also disclosed. Antibodies are disclosed that specifically bind NGEP. Methods are disclosed for using an NGEP polypeptide, an antibody that specifically binds NGEP, or a polynucleotide encoding NGEP. Assays are disclosed for the detection prostate cancer. Pharmaceutical compositions including an NGEP polypeptide, an antibody that specifically binds NGEP, or a polynucleotide encoding NGEP are also disclosed. These pharmaceutical compositions are of use in the treatment of prostate cancer. | 08-13-2009 |
| 20090304702 | GENE EXPRESSED IN PROSTATE CANCER AND METHODS OF USE - A polypeptide is disclosed that is specifically detected in the cells of the prostate, termed Splice Variant-Novel Gene Expressed in Prostate (SV-NGEP). Polynucleotides encoding SV-NGEP are also disclosed, as are vectors including these polynucleotides. Host cells transformed with these polynucleotides are also disclosed. Antibodies and immunoconjugates are disclosed that specifically bind SV-NGEP. Methods are disclosed for using an NGEP polypeptide, an antibody that specifically binds SV-NGEP, or a polynucleotide encoding SV-NGEP. Assays are disclosed for the detection prostate cancer. Pharmaceutical compositions including an SV-NGEP polypeptide, an antibody that specifically binds SV-NGEP, or a polynucleotide encoding SV-NGEP are also disclosed. These pharmaceutical compositions are of use in the treatment of prostate cancer. | 12-10-2009 |
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| 20090011966 | Lubricating Oil Composition - A lubricating oil composition having a total base number of more than 15 mg KOH/g, as determined by ASTM D2896, and including at least 40 mass % of an oil of lubricating viscosity; at least one detergent; and at least one compound of the formula (I) and/or formula (II): | 01-08-2009 |
| 20090156448 | Additive Compositions - Compositions in the form of lubricating oil compositions, greases, fuels or functional fluids containing, in the form of Michael adducts, N-substituted phenylenediamine additives in which at least one of the substituents on the N atoms carries a carbonyl group that is connected to an alkyl, alkoxyalkyl, or alkylthioalkyl group either directly or via an oxygen atom. | 06-18-2009 |
| 20090203559 | Engine Lubrication - A trunk piston or cross-head diesel engine having a centrifuge system including a sealing medium is lubricated with a lubricant which, for the cross-head engine, is a system lubricant and which contains 0.04 to 5 mass %, expressed as active ingredient, of a combination of one or more linked aromatic compounds and one or more nitrogen containing ashless disperants, in a mass:mass ratio in the range of 1:3 to 9:1. | 08-13-2009 |
