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Benjamin A.
Benjamin A. Auspitz, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090075951 | Methods and Reagents for the Treatment of Inflammatory Disorders - The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering a tricyclic compound and, optionally, a corticosteroid or other compound to the patient. The invention also features a pharmaceutical composition containing a tricyclic compound and a corticosteroid or other compound for the treatment or prevention of an immunoinflammatory disorder. | 03-19-2009 |
| 20100210606 | METHODS AND REAGENTS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - The invention features a method for treating an immunoinflammatory administering a compound of formula (I), e.g., ibudilast or KC-764, alone or in combination with a corticosteroid, tetra-substituted pyrimidopyrimidine, or other compound. The invention also features pharmaceutical compositions including the combination above for the treatment or prevention of an immunoinflammatory disorder. | 08-19-2010 |
| 20120058979 | METHODS AND REAGENTS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS - The invention features a method for treating a patient diagnosed with, or at risk of developing, an immunoinflammatory disorder by administering to the patient a tetra-substituted pyrimidopyrimidine, either alone or in combination with one or more additional agents. The invention also features a composition containing a tetra-substituted pyrimidopyrimidine in combination with one or more additional agents. | 03-08-2012 |
Benjamin A. Douts, Tewksbury, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090051415 | Ripple current reduction circuit - A ripple current reduction circuit includes a supply node coupled to the output of a high ripple voltage source such as a charge pump. A first current mirror is referred to the supply node and mirrors a current I | 02-26-2009 |
| 20090295362 | Voltage boost circuit without device overstress - A voltage boost circuit is driven with a clock signal CLK which toggles between voltages V | 12-03-2009 |
Benjamin A. Flugstad, Port Ludlow, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20120071940 | DEFIBRILLATOR WITH UTILITY LIGHT - Embodiments of the present concept are directed to external defibrillators that include a utility light for use by one or more rescuers using the defibrillator. In one implementation, an external defibrillator has a housing, an energy storage module for storing an electrical charge, a defibrillation port for guiding the stored electrical charge to a person, and a processor for determining when to guide the electrical charge. The defibrillator also includes a user interface that includes a screen showing indications by light, and a separate utility light coupled to the housing via a light-coupling structure. The utility light is structured to generate and cast a beam of light with a beam divergence angle of no more than 160 degrees in order to illuminate a certain point of the local environment. This illumination capability may help rescuers reach a person in need of medical attention and apply medical assistance to the person. | 03-22-2012 |
Benjamin A. Giannescho, Orange, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090248007 | ELECTROSURGICAL SYSTEM - An electrosurgical system can include an electrosurgical generator, a feedback circuit or controller, and an electrosurgical tool. The feedback circuit can provide an electrosurgery endpoint by determining the phase end point of a tissue to be treated. The electrosurgical system can include more than one electrosurgical tool for different electrosurgical operations and can include a variety of user interface features and audio/visual performance indicators. The electrosurgical system can also power conventional bipolar electrosurgical tools and direct current surgical appliances. | 10-01-2009 |
Benjamin A. Goldburd, Brooklyn, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090087827 | COMPUTERIZED TESTING SYSTEM - A secure testing system utilizing a test taker's own notebook computer with a small portable/removable uniquely identified drive element (USB flash drive, SD card and the like) being plugged into the computer port (USB, card reader, etc.). The drive is pre-programmed with lock-out software activated with test taker log in, and preprogrammed exams or examination generations software. The drive and examination software are configured for multiple choice selection and text entry for essay answers. With exam completion the drives are removed with restoration of computer function. The individual drives are collected and connected to multiple reading ports for automatic reading and grading of multiple choice question answers and manual checking of text answers. The exams, with identification of disk drives and test taker are downloaded to an archive server and the drives are wiped clean for re-use. Test results and comments are sent via e-mail to the test taker. | 04-02-2009 |
Benjamin A. Mancuse, Schenectady, NY US
Benjamin A. Perrot, Greensboro, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090275076 | CELL SAMPLE PREPARATION METHOD AND APPARATUS - An apparatus and method for automatic thin-layer cell sample slide preparation without requiring human intervention are disclosed. According to one embodiment, a cell sample is measured to derive a cell sample measurement. An estimation of total cellularity of the cell sample is determined based upon the cell sample measurement. A differential volume of diluent is dispensed to the cell sample based upon the estimation of total cellularity of the cell sample to form a cell suspension. In one embodiment, a differential volume of the cell suspension and a differential volume of cell adherent may be combined based upon the estimation of total cellularity of the cell sample to form a cell mixture. A differential volume of the cell suspension or cell mixture (if an adherent is mixed with the cell suspension) is dispensed onto a surface of a sample slide. | 11-05-2009 |
Benjamin A. Rosenkrans, Painted Post, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110204030 | RETAINER, VACUUM INTERRUPTER, AND ELECTRICAL SWITCHING APPARATUS INCLUDING THE SAME - A vacuum interrupter includes a number of insulative tubes having a first open end and a second open end; a first end member secured to the first open end; a second end member secured to the second open end; a fixed contact mounted on a fixed electrode extending through the second end member; a retainer; and a movable contact. The retainer includes a rigid retainer having a plurality of legs and an opening, and an insulative bushing having a smaller opening. The insulative bushing is molded over a portion of the rigid retainer. The smaller opening is within the opening of the rigid retainer and is structured to receive a movable electrode. The movable contact is mounted on the movable electrode extending through the first end member and through the smaller opening. The movable contact is capable of axially reciprocating into and out of contact with the fixed contact. | 08-25-2011 |
Benjamin A. Saarloos, Orlando, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20080210406 | METHOD AND APPARATUS FOR HIGH HEAT FLUX HEAT TRANSFER - The subject invention pertains to a method and apparatus for high heat flux heat transfer. The subject invention can be utilized to transfer heat from a heat source to a coolant such that the transferred heat can be effectively transported to another location. Examples of heat sources from which heat can be transferred from include, for example, fluids and surfaces. The coolant to which the heat is transferred can be sprayed onto a surface which is in thermal contact with the heat source, such that the coolant sprayed onto the surface in thermal contact with the heat absorbs heat from the surface and carries the absorbed heat away as the coolant leaves the surface. The surface can be, for example, the surface of an interface plate in thermal contact with the heat source or a surface integral with the heat source. The coolant sprayed onto the surface can initially be a liquid and remain a liquid after absorbing the heat, or can in part or in whole be converted to a gas or vapor after absorbing the heat. The coolant can be sprayed onto the surface, for example, as a stream of liquid after being atomized, or in other ways which allow the coolant to contact the surface and absorb heat. Once the heat is absorbed by the coolant, the coolant can be transported to another location so as to transport the absorbed heat as well. | 09-04-2008 |
| 20090294097 | Method and Apparatus for Heating or Cooling - Embodiments of the subject invention pertain to a method and apparatus for heating or cooling. Embodiments relate to a method and apparatus utilizing a vapor compression cycle to accomplish active heating or cooling. In a specific embodiment, the subject invention relates to a lightweight, compact, reliable, and efficient heating or cooling system for underwater applications. The subject system can provide heating or cooling stress relief to individuals operating under, for example, hazardous conditions, or in low temperature underwater environments where passive protective clothing provides insufficient mitigation of cooling stress. Further embodiments can be utilized to provide heat stress relief to users who are working in thermally encapsulated ensembles that hinder the body's natural ability to expel heat. The subject system can be utilized in other applications that can benefit from this type of heating or cooling system. The performance of this system cannot be matched simply by using smaller versions of currently available designs or technologies. | 12-03-2009 |
Benjamin A. Schnitz, Nashville, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20110227727 | DEVICE, SYSTEM AND METHOD FOR TRACKING MOBILE ASSETS - A device attached to an outside surface of a shipping container for tracking the shipping container includes a solar panel, a battery, a GPS receiver module, a cellular data transceiver module, and a microcontroller for controlling the GPS receiver module and the cellular data transceiver module to periodically obtain the location of the shipping container and transmit the location to a tracking database of a central tracking computer. The solar panel, battery, GPS receiver module, cellular data transceiver module and microcontroller are integrated into a one-piece, watertight master control unit. The master control unit may further include a local wireless network master transceiver module. The local wireless network master transceiver module is for communicating with a wireless sensor located within the shipping container through the walls of the shipping container. | 09-22-2011 |
Benjamin A. Seigal, Watertown, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100152099 | MACROCYCLIC COMPOUNDS FOR INHIBITION OF TUMOR NECROSIS FACTOR ALPHA - The invention provides macrocyclic compounds and methods for their synthesis and use. In particular, the invention provides macrocyclic compounds that modulate the activity of tumor necrosis factor alpha and/or are useful in the treatment of medical conditions, such as, rheumatoid arthritis, psoriasis, and asthma. | 06-17-2010 |
| 20100159446 | Detection Assays and Use Thereof - The invention provides compositions and methods for the detection and/or quantification of biological targets (e.g., nucleic acids and proteins) by the nucleic acid-templated creation of one or more reaction products, for example, epitopes, enzyme substrates, enzyme activators, and ligands. The reaction products can be detected and/or quantitated after signal amplification using an amplification system. | 06-24-2010 |
Benjamin A. Shobert, Indianapolis, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20110247162 | APPLICATOR WITH FLEXIBLE PAD AND HANDLE - A liquid applicator includes a frame and a flexible applicator pad. The frame includes an elongated handle that presents opposite handle margins and extends in a longitudinal direction between the margins. The flexible applicator pad presents opposite applicator pad ends. The handle margins are coupled relative to the flexible applicator pad adjacent corresponding applicator pad ends. The handle presents an intermediate region that is flexible and spaced from the pad, with the liquid applicator thereby being shiftable into and out of a relaxed applicator condition. | 10-13-2011 |
| 20120023695 | APPLICATOR WITH INDIVIDUALLY FLEXIBLE PAD SUPPORT FINGERS - A liquid applicator is configured to apply liquid to a contoured surface. The liquid applicator includes a frame with a laterally extending base and a plurality of elongated fingers spaced laterally along the base. The fingers flex to follow the contoured surface when a liquid application force is applied. The liquid applicator also includes a flexible applicator pad assembly supported on multiple ones of the fingers. The applicator pad assembly is operable to carry liquid and is flexible at least generally with the fingers so as to follow the contoured surface during liquid application | 02-02-2012 |
Benjamin A. Teply, Omaha, NE US
| Patent application number | Description | Published |
|---|---|---|
| 20100266491 | SYSTEM FOR TARGETED DELIVERY OF THERAPEUTIC AGENTS - The present invention provides a drug delivery system for targeted delivery of therapeutic agent-containing particles to tissues, cells, and intracellular compartments. The invention provides targeted particles comprising a particle, one or more targeting moieties, and one or more therapeutic agents to be delivered and pharmaceutical compositions comprising inventive targeted particles. The present invention provides methods of designing, manufacturing, and using inventive targeted particles and pharmaceutical compositions thereof. | 10-21-2010 |
| 20100323199 | POLYMERS FOR FUNCTIONAL PARTICLES - The present invention generally relates to polymers and macromolecules, in particular, to block polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of developing nanoparticles with desired properties. In one set of embodiments, the method includes producing libraries of nanoparticles having highly controlled properties, which can be formed by mixing together two or more macromolecules in different ratios. One or more of the macromolecules may be a polymeric conjugate of a moiety to a biocompatible polymer. In some cases, the nanoparticle may contain a drug. The moiety, in some embodiments, may have a molecular weight greater than about 1000 Da; for example, the moiety may include a polypeptide or a polynucleotide, such as an aptamer. The moiety may also be a targeting moiety, an imaging moiety, a chelating moiety, a charged moiety, or a therapeutic moiety. Another aspect of the invention is directed to systems and methods of producing such polymeric conjugates. In some embodiments, a solution containing a polymer is contacted with a liquid, such as an immiscible liquid, to form nanoparticles containing the polymeric conjugate. Other aspects of the invention are directed to methods using such libraries, methods of using or administering such polymeric conjugates, methods of promoting the use of such polymeric conjugates, kits involving such polymeric conjugates, or the like. | 12-23-2010 |