Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Belke
Darrell H. Belke, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080313753 | Compositions and Methods for Improving Heart Function - The present invention relates to treating or ameliorating heart disease associated with poor myocardial performance, e.g., diabetic cardiomyopathy and associated disorders, particularly to treating, preventing or ameliorating such disorders through inhibition of O-GlcNAcylation and/or increased activity of O-GlnNAcase. The invention provides vectors for gene transfer of O-GlnNAcase. In one aspect, the invention provides cells, vectors, formulations comprising them and methods of using them, for the gene transfer of the human O-GlnNAcase gene, e.g., to treat conditions and diseases associated with impaired cardiac contractility, such as that, found associated with diabetic cardiomyopathy. In another aspect, the invention provides non-human transgenic animals and host cells comprising genetically engineered cells having increased activity of O-GlnNAcase. | 12-18-2008 |
Jeffrey Victor Belke, Western Australia AU
| Patent application number | Description | Published |
|---|---|---|
| 20110180484 | SEPARATION DEVICE WITH DUAL DRIVES AND A METHOD OF REDUCING DONUTTING IN A SEPARATION DEVICE - The invention provides a separation device ( | 07-28-2011 |
Marianne Belke, Jena DE
| Patent application number | Description | Published |
|---|---|---|
| 20110219788 | CRYOGENIC STORAGE DEVICE - The invention relates to a cryogenic storage device and to a method for operating a cryogenic storage device, particularly for cryogenic storage of biological samples, comprising a sample carrying device that is set up to accommodate samples, a cryogenic container that is set up to accommodate the sample carrying device, a container cooling device with which the cryogenic container can be cooled, an intermediate storage container that is set up for intermediate storage of the sample carrying device, a transport device with which the sample carrying device can be moved between the cryogenic container and the intermediate storage container and a sensor device with which at least one operating parameter of the cryogenic storage device can be registered. The transport device is set up to be activated in dependence on an output signal from the sensor device upon registering a predetermined operating condition of the cryogenic storage device, so that the sample carrying device is moved from the cryogenic container to the intermediate storage container. Additionally or alternatively, an intermediate storage cooling device that is set up for cooling the intermediate storage container can be activated in dependence on an output signal of the sensor device. | 09-15-2011 |