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Beerli
Martin Beerli, Frauenfeld CH
| Patent application number | Description | Published |
|---|---|---|
| 20100132459 | Device and method for arranging a housing in a specified position relative to a reference object - For positioning and/or aligning a housing with respect to a reference object, a detachable positioning means is constructed on the housing. The positioning means comprises at least one stop element that is brought into contact with the reference object. After mounting the housing in the desired position, the positioning means is separated from the housing. | 06-03-2010 |
Rene Beerli, Binningen CH
| Patent application number | Description | Published |
|---|---|---|
| 20090069360 | Organic Compounds - The present invention relates to the discovery that certain compounds inhibit, regulate and/or modulate tyrosine and serine/threonine kinase and kinase-like proteins, such as RAF kinase, a serine/threonine kinase that functions in the MAP kinase signaling pathway, and is concerned with compositions which contain these compounds, and methods of using them to treat tyrosine and serine/threonine kinase and kinase-like dependent diseases, such as angiogenesis, cancer and cardiac hypertrophy. | 03-12-2009 |
| 20090074791 | Phenylisoquinoline and Phenylquinazoline Derivatives - The present invention relates to substituted phenylisoquinoline and phenylquinazoline derivatives and to their pharmaceutical uses in preventing or treating bone conditions which are associated with increased calcium depletion or resorption or in which stimulation of bone formation and calcium fixation in the bone is desirable. | 03-19-2009 |
| 20100166765 | BENZOQUINAZOLINE DERIVATIVES - A compound of formula (I) or a pharmaceutically acceptable salt or prodrug ester thereof, wherein the groups R2, R3, R4, Q, X and Y are as defined in the specification, is useful in the treatment of bone conditions related to increased calcium depletion or resorption. | 07-01-2010 |
Rene Beerli, Basel CH
| Patent application number | Description | Published |
|---|---|---|
| 20100063075 | Aryl-quinazoline/aryl-2amino-phenyl methanone derivatives - A compound of formula (1): wherein R1, R2, R3 and Y are as defined herein, or a pharmaceutically-acceptable and -cleavable ester, or acid addition salt thereof, useful for promoting the release of parathyroid hormone, e.g. for preventing or treating bone conditions which are associated with increased calcium depletion or resorption or in which stimulation of bone formation and calcium fixation in the bone is desirable. | 03-11-2010 |
Roger Beerli, Adlikon CH
| Patent application number | Description | Published |
|---|---|---|
| 20100292089 | SELECTION OF HUMAN MONOCLONAL ANTIBODIES BY MAMMALIAN CELL DISPLAY - The application provides a method of isolating a eukaryotic cell expressing an antibody of desired specificity, preferably a monoclonal single chain antibody (scFv). The application further provides methods which allow to clone the variable regions of said antibody from that isolated eukaryotic cell and to recombinantly produce antibodies comprising said variable regions as fusion protein with a purification tag, eg. as Fc-fusion, as a Fab fragment, or as whole antibodies, such as IgG, IgE, IgD, IgA and IgM. Said methods also allows to recombinantly produce antibodies with desired specificity in a fully species specific form, preferably as fully human antibodies. | 11-18-2010 |
Roger Beerli, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080318839 | Ligand activated transcriptional regulator proteins - Fusion proteins for use as ligand-dependent transcriptional regulators are provided. The fusion proteins include a nucleotide binding domain operatively linked to a ligand-binding domain. They also can include a transcription regulating domain. The nucleotide binding domain is a zinc-finger peptide that binds to a targeted contiguous nucleotide sequence of from 3 to about 18 nucleotides are provided. The fusion proteins are used for gene therapy. Also provided are polynucleotides encoding the fusion proteins, expression vectors, and transfected cells. | 12-25-2008 |
Roger Beerli, Adlikon B. Regensdorf CH
| Patent application number | Description | Published |
|---|---|---|
| 20110123541 | Human Monoclonal Nicotine Specific Antibodies - The invention relates to recombinantly produced human monoclonalantibodies which are specifically binding nicotine and to nucleic acids encoding the same. The invention further relates to the use of such antibodies in the treatment of nicotine addiction. | 05-26-2011 |