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Beebe, US
Brian Beebe, Detroit, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110252677 | FLOWING WATER DISPLAY - A flowing water display including a transparent upright backwall panel covering a graphic art sheet and water sprayed from a spray tube against a forward surface of the panel to cause a down flow of water thereover, with an open topped reservoir tank disposed beneath the panel to collect said water down flow, which is recirculated by a pump drawing water out of the reservoir tank and pumping water back into the spray tube. A pair of removable side channels and top channel frame the graphic art image and conceal the spray tube and plumbing connection to the pump. The components of a wall mounted version allow separate mounting to make a wall mount easier for large size displays. | 10-20-2011 |
Clifford A. Beebe, Snohomish, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090192659 | AIRCRAFT MAINTENANCE LAPTOP - An apparatus comprises a portable computer, and program code stored on the portable computer. The program code is capable of being executed to establish a communications link with an aircraft network data processing system in an aircraft, obtain information about the aircraft over the communications link, display the information on a display device for the portable computer, receive user input to control a data processing system on the aircraft network data processing system in the aircraft, and send a number of commands to the data processing system in response to receiving the user input. | 07-30-2009 |
Dana C. Beebe, Houston, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090038805 | CONTROL MODULE FOR SUBSEA EQUIPMENT - A subsea control module for providing control of subsea equipment is provided. The design allows for replacement and retrieval of a subsea control module with a single remotely operated vehicle (“ROV”) deployment from a vessel. The subsea control module can provide distributed electrical and hydraulic control functions via multiple directional control valve modules, multiple pilot valve modules, and a central electronic control module. Each directional control and pilot perform a set of functions so that replacement of a single module does not require disassembly of any other components) or hydraulic connection. Similarly, each pilot valve module can include a set of pilot valves, pressure transducers, solenoids and electronic circuitry to perform a limited set of functions so that failure of a single pilot valve module does not result in failure of the entire subsea control module. The central electronic control module can provide electrical signals to each pilot valve module which can provide hydraulic signals to each directional control valve module and to off-board hydraulics through a subsea equipment receptacle mated with the subsea control module. | 02-12-2009 |
| 20090194290 | CONTROL SYSTEM FOR BLOWOUT PREVENTER STACK - A modular control system consisting of multiple, remotely retrievable functional modules for controlling a blowout preventer stack. The various functional modules can be located on the lower marine riser package and blowout preventer stack positioned near the equipment with which they are associated, wherein this distribution of modules nearly eliminates the complex interface connection between the lower marine riser package and blowout preventer stack. Each of the functional modules is capable of being installed, retrieved or replaced with a single remotely operated vehicle (ROV) deployment from a vessel. The functional modules can be used to operate as a complete control system for a blowout preventer stack or can be used selectively individually or in various combinations to accommodate multiple control applications or upgrades of other control systems. | 08-06-2009 |
Jane A. Beebe, Elkhorn, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20100240080 | KINASE AND PHOSPHATASE ASSAYS - Compositions, methods, and kits for detecting and monitoring kinase, phosphatase and protein post-translational modification activity are described. The compositions typically include a peptide, a detectable moiety, and a protease cleavage site. Modification of a peptide by a kinase, phosphatase or other protein post-translational modification alters the proteolytic sensitivity of the peptide, resulting in a change of a detectable property of the composition. Panel assays for determining substrates or modulators of kinase, phosphatase or other protein post-translational modification activity are also described. | 09-23-2010 |
| 20120083427 | KINASE AND PHOSPHATASE ASSAYS - Compositions, methods, and kits for detecting and monitoring kinase, phosphatase and protein post-translational modification activity are described. The compositions typically include a peptide, a detectable moiety, and a protease cleavage site. Modification of a peptide by a kinase, phosphatase or other protein post-translational modification alters the proteolytic sensitivity of the peptide, resulting in a change of a detectable property of the composition. Panel assays for determining substrates or modulators of kinase, phosphatase or other protein post-translational modification activity are also described. | 04-05-2012 |
Jason Beebe, Gilbert, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20110213837 | System and Method for Evaluating and Analyzing Content - A system for evaluating content includes a plurality of client computer systems, each one of the client computer systems configured to perform the steps of playing content on a media player; capturing, while the content is playing, a plurality of ratings from a user, each one of the ratings corresponding to a different play time; and sending the plurality of ratings and the corresponding play times to a media analyzer. The system further includes the media analyzer configured to perform the steps of, from a plurality of users, receiving a plurality of ratings and corresponding play times; grouping the ratings and corresponding play times according to content being rated; and analyzing the grouped ratings. Preferably, the media analyzer can store ratings from different content being played and evaluated simultaneously. | 09-01-2011 |
Jean Beebe, Salem, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100255538 | ANTIBODIES TO INSULIN-LIKE GROWTH FACTOR I RECEPTOR - The present invention relates to antibodies and antigen-binding portions thereof that specifically bind to insulin-like growth factor I receptor (IGF-IR), which is preferably human IGF-IR. The invention also relates to human anti-IGF-IR antibodies, including chimeric, bispecific, derivatized, single chain antibodies or portions of fusion proteins. The invention also relates to isolated heavy and light chain immunoglobulin molecules derived from anti-IGF-IR antibodies and nucleic acid molecules encoding such molecules. The present invention also relates to methods of making anti-IGF-IR antibodies, pharmaceutical compositions comprising these antibodies and methods of using the antibodies and compositions thereof for diagnosis and treatment. The invention also provides gene therapy methods using nucleic acid molecules encoding the heavy and/or light immunoglobulin molecules that comprise the human anti-IGF-IR antibodies. The invention also relates to gene therapy methods and transgenic animals comprising nucleic acid molecules of the present invention. | 10-07-2010 |
| 20120005767 | ANTIBODIES TO INSULIN-LIKE GROWTH FACTOR I RECEPTOR - The present invention relates to antibodies and antigen-binding portions thereof that specifically bind to insulin-like growth factor I receptor (IGF-IR), which is preferably human IGF-IR. The invention also relates to human anti-IGF-IR antibodies, including chimeric, bispecific, derivatized, single chain antibodies or portions of fusion proteins. The invention also relates to isolated heavy and light chain immunoglobulin molecules derived from anti-IGF-IR antibodies and nucleic acid molecules encoding such molecules. The present invention also relates to methods of making anti-IGF-IR antibodies, pharmaceutical compositions comprising these antibodies and methods of using the antibodies and compositions thereof for diagnosis and treatment. The invention also provides gene therapy methods using nucleic acid molecules encoding the heavy and/or light immunoglobulin molecules that comprise the human anti-IGF-IR antibodies. The invention also relates to gene therapy methods and transgenic animals comprising nucleic acid molecules of the present invention. | 01-05-2012 |
Joel Beebe, Columbus, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20110248127 | Display - Devices are disclosed having a magnet disposed thereon, operatively configured for retaining a ferrous element thereagainst. | 10-13-2011 |
Kevin Beebe, Spencerport, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090302488 | METHOD AND APPARATUS FOR THE DRY RELEASE OF A COMPLIANT OPHTHALMIC ARTICLE FROM MOLD SURFACE - An apparatus for releasing a molded lens from a deformable mold includes a shear ring for temporarily retaining an annular portion of the deformable mold outside a periphery of the lens and a plunger for deforming an annular section of the deformable mold within the periphery of the lens. The apparatus can be employed to release a non-hydrated hydrogel lens from a deformable mold section. | 12-10-2009 |
| 20120001353 | METHOD AND APPARATUS FOR THE DRY RELEASE OF A COMPLIANT OPHTHALMIC ARTICLE FROM A MOLD SURFACE - An apparatus for releasing a molded lens from a deformable mold includes a shear ring for temporarily retaining an annular portion of the deformable mold outside a periphery of the lens and a plunger for deforming an annular section of the deformable mold within the periphery of the lens. The apparatus can be employed to release a non-hydrated hydrogel lens from a deformable mold section. | 01-05-2012 |
Kevin D. Beebe, Spencerport, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090135410 | Bubble reduction system - An ophthalmic device forming system includes an inspection station configured to receive a plurality of ophthalmic devices, a fluid supply fluidly connected to the inspection station, the fluid supply containing a working fluid, and a heat source fluidly connected between the fluid supply and the inspection station. The heat source includes a housing, a transfer element, and a low pressure gas region defined by the housing adjacent to the transfer element. | 05-28-2009 |
| 20090145456 | Ultrasonic Bubble Reduction System - An inspection system includes an inspection station configured to receive a plurality of ophthalmic devices, and a fluid supply fluidly connected to the inspection station. The fluid supply contains a working fluid. The system also includes an ultrasonic degassing assembly configured to remove at least one bubble carried by the plurality of ophthalmic devices upstream of a packaging station. | 06-11-2009 |
| 20090145462 | Maintaining an Ophthalmic Device in a Hydrated State - An ophthalmic device hydration system includes an inspection station configured to receive a plurality of ophthalmic devices and fluid supply fluidly connected to the inspection station. The fluid supply contains a working fluid. The ophthalmic device hydration system also includes a hydration assembly disposed proximate the inspection station and configured to vaporize a volume of the working fluid. | 06-11-2009 |
Melanie Beebe, Apex, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100310640 | HLA-DR BINDING PEPTIDES AND THEIR USES - The present invention provides HLA-DR (MHC class II) binding peptides derived from the ovarian/breast cancer associated antigens, Human Epidermal Growth Factor Receptor 2 (HER-2/neu), Carcinoembryonic Antigen (CEA), Insulin Growth Factor Binding Protein 2 (IGFBP-2), and Cyclin D1. The immunogenic peptides can be used in cancer vaccines. | 12-09-2010 |
Michael Beebe, Norwalk, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20110144955 | SYSTEM FOR MODELING DYNAMIC RESPONSE CHANGES IN AN ANTHROPOMORPHIC DUMMY - A system and method for designing a crashworthiness system is taught. The system utilizes computer models of anthropomorphic dummies having material properties which change as a function of time. | 06-16-2011 |
Randolph R. Beebe, Duluth, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20080282306 | Mapping Transport Streams - In a digital network that includes a plurality of devices, which include multiple devices that transmit transport streams, a system and method are provided for discovering and mapping the transport streams and the plurality of devices included in the digital network. One such method sends a transport stream map request to a plurality of network devices. The network devices include a plurality of network transport stream sources and a plurality of network transport stream handlers. The method receives a plurality of replies to the transport stream map request. Each reply includes information associated with the respective network device. The method generates a transport stream map based on the received replies. The transport stream map represents a flow of transport streams among the plurality of network devices. | 11-13-2008 |
Robert M. Beebe, Raleigh, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090221872 | Endoscope Tip Protector - The invention provides an endoscope tip protector for protecting the distal tip of an endoscope and an endoscope assembly including the tip protector affixed thereto. The endoscope tip protector can include a main body with an opening through the main body sized to accept an endoscope sheath and a white surface arranged to face a distal end of an endoscope sheath when the sheath is placed in the endoscope tip protector. Methods of making and using the tip protector and assembly are also provided. | 09-03-2009 |
Ross L. Beebe, Mentor, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20100261927 | Process for Making Substituted Trithiocarbonate Derivatives - The present invention provides a low cost technique for synthesizing substituted trithiocarbonates and derivates thereof, by a one-step process which does not require solvent washes or re-crystallization steps, and results in practical yields more than double that of processes disclosed in the prior art. | 10-14-2010 |
Sarah Beebe, Herndon, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20120030729 | COLLABORATIVE STRUCTURED ANALYSIS SYSTEM AND METHOD - Methods, systems, and apparatus for providing compartmented, collaborative, integrated, automated analytics to analysts are provided. In a first aspect, the present invention provides a computer-implemented method for providing compartmented, collaborative, integrated, automated analytics to analysts including: selecting a computer-encoded project-specific workflow; determining a computer-encoded compartment manager, said computer-encoded compartment manager including computer-encoded information about the context of said project-specific workflow; retrieving said computer-encoded information about the context; selecting a computer-implemented automated analytic using said computer-encoded project-specific workflow; providing under control of said computer-encoded compartment manager said information about the context to said automated analytic; processing said computer-encoded information using said computer-implemented automated analytic, to generate thereby analytical information representing an outcome to said analysts; and processing said analytical information in accordance with said computer-encoded compartment manager and said computer-encoded project-specific workflow. | 02-02-2012 |
Simon Beebe, Groton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110060948 | DIAGNOSTICS METHODS FOR A COMMUNICATIONS DEVICE - A method facilitating the support of a communications device via diagnostic tools on the communications device and a remote computing device of monitoring predefined data elements associated with the operation of said communications device. | 03-10-2011 |
Stephen Beebe, Norfolk, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20090125091 | ULTRAWIDEBAND ANTENNA FOR OPERATION IN TISSUE - Method and apparatus for cellular and intracellular manipulation of cell functions with ultrashort electrical pulses and for targeted delivery of the electrical pulses into cell cultures, patients, and tissues. | 05-14-2009 |
Stephen J. Beebe, Norfolk, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20090299417 | DELIVERY DEVICE, SYSTEM, AND METHOD FOR DELIVERING NANOSECOND PULSED ELECTRIC FIELDS - A medical instrument for delivering electrotherapy to tissue that includes an outer support member having a ground plate at a distal end of the outer support member, and a protrusive element having a tip that extends beyond the ground plate. A portion of the protrusive element proximate the ground plate can act as an electrical insulator and a portion of the protrusive element proximate the distal end of the protrusive element can include a first electrode. The protrusive element can be designed to penetrate into tissue below a tissue surface while a tissue contacting surface of the ground plate rests against the tissue surface. Also disclosed are systems incorporating the medical instrument and methods of electrotherapy to subsurface tissue using the medical instrument. | 12-03-2009 |
| 20110092973 | NANOSECOND PULSED ELECTRIC FIELDS CAUSE MELANOMAS TO SELF-DESTRUCT - Methods for a new, drug-free therapy for treating solid skin tumors through the application of nanosecond pulsed electric fields (“nsPEFs”) are provided. In one embodiment of the invention, the cells are melanoma cells, and the applied nsPEFs penetrate into the interior of tumor cells and cause tumor cell nuclei to rapidly shrink and tumor blood flow to stop. This new technique provides a highly localized targeting of tumor cells with only minor effects on overlying skin. | 04-21-2011 |
| 20110236979 | Apparatus for Generating Electrical Pulses and Methods of Using Same - A method and apparatus are provided for delivering an agent into a cell through the application of nanosecond pulse electric fields (“nsPEF's”). The method includes circuitry for delivery of an agent into a cell via known methods followed by the application of nanosecond pulse electric fields to said cell in order to facilitate entry of the agent into the nucleus of the cell. In a preferred embodiment, the present invention is directed to a method of enhancing gene expression in a cell comprising the application of nanosecond pulse electric fields to said cell. An apparatus for generating long and short pulses according to the present invention is also provided. The apparatus includes a pulse generator capable of producing a first pulse having a long duration and low voltage amplitude and a second pulse having a short duration and high voltage amplitude. | 09-29-2011 |
| 20110288545 | Method and Device for Ablation of Cancer and Resistance to New Cancer Growth - Methods and devices designed to eliminate and/or ablate cancer or other abnormal growths of cells or tissues or eliminate and/or ablate cells or tissue with abnormal functions. In particular, using sub-microsecond electric pulses to treat cancer cells by, inter alia, inducing programmed cell death or other type of cell death. These methods and devices are expected to greatly improve the prevention, treatment and management of cancer by increasing the effectiveness of cancer treatments and development of resistance to new cancer growth. | 11-24-2011 |
| 20110318319 | ACTIVATION and AGGREGATION OF HUMAN PLATELETS AND FORMATION OF PLATELET GELS BY NANOSECOND PULSED ELECTRIC FIELDS - Methods for forming activated platelet gels using nsPEF's and applying the activated gels to wounds, such as heart tissue after myocardial infarction. The platelets are activated by applying at least one nsPEF with a duration between about 10 picoseconds to 1 microsecond and electrical field strengths between about 10 kV/cm and 350 kV/cm. | 12-29-2011 |
Stephen P. Beebe, Norfolk, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20120109263 | Medical Instrument for Delivery of High Voltage Pulses and Method of Delivering the Same - An instrument | 05-03-2012 |
W. Scott Beebe, Berkley, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110073613 | FLUID DISPENSING SYSTEM - A fluid dispenser is disclosed where a backoff distance is determined and implemented to prevent leakage while dispensing sequentially an accurate, precise amount of fluid substantially independent of the fluid remaining in a syringe-type dispenser. The fluid characteristics of the fluid, e.g. viscosity, surface tension, etc. affect the backoff distance that may be determined heuristically for fluid type, amount of fluid remaining in the syringe and amount to be dispensed. Once the fluid characteristics are known, the dispensing may be accomplished automatically with a processor loading new drive and backoff steps to a motor controller. | 03-31-2011 |
| 20110101035 | PROTECTIVE SYRINGE SLEEVE - A protective sleeve placed within the cylinder of a syringe, the sleeve protects a piston and a computer controlled device or human operator pushing the piston from material leaking past a piston assembly. The sleeve has lips or ridges at either end, one that is attached to the piston assembly at the output end of the syringe and a second lip that is attached with a retention plate at the far end of the syringe. The sleeve may have a bellows or accordion configuration that slides along the inner surface of the syringe cylinder without appreciably loading the drive mechanism. | 05-05-2011 |
| 20110245983 | REMOTELY CONTROLLED FLUID DISPENSER - A network of fluid dispensers is disclosed where a Host controller may exchange information with local dispensers, and where local dispensers may exchange information with each other. The information may be dispensing processes, information regarding quality and reliability, problems and/or helpful information, and applications. The information may be exchanged in real time during fluid dispensing where any issues may be shared and resolved quickly even in remote locales. The applications may be developed at a local dispenser or at the Host and then shared throughout the network. The operating systems may include application software development tools, and the applications may include: monitoring deliver schedules and materials inventories; automatic issuing of purchase orders; training broadcasts; implementing industry standards for validation and approval. | 10-06-2011 |
| 20110245984 | VIRTUAL DISPENSING SYSTEM - A network of fluid dispenser systems is disclosed where a Host/Server is a virtual controller for a number of fluid dispensers systems. The virtual controller may exchange information with local dispenser systems, that incorporate virtual controlling functions. The information may be dispensing processes, information regarding quality and reliability, problems and/or helpful information, and applications. An application may include synchronizing multiple dispensing syringe assemblies. The information may be exchanged in real time during fluid dispensing where any issues may be shared and resolved quickly even in remote locales. Information may be distributed among the disparate locations. | 10-06-2011 |