| Patent application number | Description | Published |
| 20080255994 | Content Preview - Techniques enable creation of a preview license for digital content. In some instances, the preview license indicates that it allows a content-consuming device to consume less than all of the content. This preview license may create a list specifying multiple portions of the digital content that the content-consuming device may consume. These techniques may also present to a device user an offer to purchase rights to consume all of the digital content after consumption of the preview-licensed portion(s). In other instances, a content server may embed the preview license into a content package that contains the digital content, allowing the server to distribute the package to multiple devices. In still other instances, the preview license may be bound to a domain rather than to individual devices. This allows member devices to share the digital content and the preview license, such that each member device may enjoy the preview experience. | 10-16-2008 |
| 20080256592 | Managing Digital Rights for Multiple Assets in an Envelope - Techniques enable building a collection of data that defines an asset, with the data possibly having differing data types. These techniques are then capable of assigning arbitrary policy to that asset, regardless of which data types are present within the asset. In addition, these techniques enable packaging of this first asset with one or more additional assets in a self-contained envelope. Each asset within the envelope may similarly include data of differing data types. Furthermore, each of these assets may be assigned a policy that may be different than the policy assigned to the first asset. This envelope, or a collection of envelopes, may then be provided to a content-consuming device to consume the assets in accordance with each asset's specified policy. | 10-16-2008 |
| Patent application number | Description | Published |
| 20090137817 | SPATIALLY-DEFINED MACROCYCLIC COMPOUNDS USEFUL FOR DRUG DISCOVERY - Novel spatially-defined macrocyclic compounds containing specific conformational control elements are disclosed. Libraries of these macrocycles are then used to select one or more macrocycle species that exhibit a specific interaction with a particular biological target. In particular, compounds according to the invention are disclosed as agonists or antagonists of a mammalian motilin receptor and a mammalian ghrelin receptor. | 05-28-2009 |
| 20090198050 | Macrocyclic Modulators of the Ghrelin Receptor - The present invention provides novel conformationally-defined macrocyclic compounds that have been demonstrated to be selective modulators of the ghrelin receptor (growth hormone secretagogue receptor, GHS-R1a and subtypes, isoforms and variants thereof). Methods of synthesizing the novel compounds are also described herein. These compounds are useful as agonists of the ghrelin receptor and as medicaments for treatment and prevention of a range of medical conditions including, but not limited to, metabolic and/or endocrine disorders, gastrointestinal disorders, cardiovascular disorders, obesity and obesity-associated disorders, central nervous system disorders, genetic disorders, hyperproliferative disorders and inflammatory disorders. | 08-06-2009 |
| 20090240027 | INTERMEDIATES FOR MACROCYCLIC COMPOUNDS - The present invention is directed to novel macrocyclic compounds of formula (I) and their pharmaceutically acceptable salts, hydrates or solvates: | 09-24-2009 |
| 20090312540 | SPATIALLY-DEFINED MACROCYCLES INCORPORATING PEPTIDE BOND SURROGATES - Novel spatially-defined macrocyclic compounds incorporating peptide bond surrogates are disclosed. Libraries of these macrocycles are then used to select one or more macrocycle species that exhibit a specific interaction with a particular biological target, in particular, compounds according to the invention are disclosed as agonists or antagonists of a mammalian motilin receptor and a mammalian ghrelin receptor. | 12-17-2009 |
| 20110105389 | Macrocyclic Ghrelin Receptor Antagonists and Inverse Agonists and Methods of Using the Same - The present invention provides novel conformationally-defined macrocyclic compounds that have been demonstrated to be selective modulators of the ghrelin receptor (GRLN, growth hormone secretagogue receptor, GHS-R1a and subtypes, isoforms and/or variants thereof). Methods of synthesizing the novel compounds are also described herein. These compounds are useful as antagonists or inverse agonists of the ghrelin receptor and as medicaments for treatment and prevention of a range of medical conditions including, but not limited to, metabolic and/or endocrine disorders, obesity and obesity-associated disorders, appetite or eating disorders, addictive disorders, cardiovascular disorders, gastrointestinal disorders, genetic disorders, hyperproliferative disorders, central nervous system disorders and inflammatory disorders. | 05-05-2011 |
| 20110245459 | Processes for Intermediates for Macrocyclic Compounds - The present invention is directed to novel macrocyclic compounds of formula (I) and their pharmaceutically acceptable salts, hydrates or solvates: | 10-06-2011 |