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Beattie, US
Craig Beattie, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20080226560 | COMPOSITIONS AND METHODS TO PREVENT CANCER WITH CUPREDOXINS - The present invention discloses methods and materials for delivering a cargo compound into a cancer cell. Delivery of the cargo compound is accomplished by the use of protein transduction domains derived from cupredoxins. The cargo compound may be a nucleic acid and specifically a DNA, RNA or anti-sense. The invention further discloses methods for treating cancer and diagnosing cancer. | 09-18-2008 |
| 20090202441 | COMPOSITIONS AND METHODS TO PREVENT CANCER WITH CUPREDOXINS - The present invention discloses methods and materials for killing and/or inhibiting the growth of a cancer cell via preferential entry of a cytotoxic compound. Preferential entry of the cytotoxic compound is accomplished by the use of protein transduction domains derived from cupredoxins, including the p18 and p28 truncations of azurin. | 08-13-2009 |
| 20090215692 | COMPOSITIONS AND METHODS TO PREVENT CANCER WITH CUPREDOXINS - The present invention relates to compositions and methods comprising chemopreventive agents that may be cupredoxin(s) or variants, derivatives and structural equivalents of cupredoxins, and at least one other chemopreventive agent. Specifically, these compositions may comprise azurin from | 08-27-2009 |
Craig W. Beattie, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20090286719 | MODIFICATION OF CUPREDOXIN DERIVED PEPTIDES AND METHODS OF USE THEREOF - The present invention provides modified cupredoxin derived peptides with pharmacologic activity that have improved pharmacokinetic properties, and methods to use them to treat mammals suffering from various conditions related to the pharmacologic activities. Modifications of the cupredoxin derived peptides include amino acid sequence variants and structural derivations that increase the plasma half-life of the peptide, increase the specific activity of the pharmacologic activity, decrease immunogenicity, and decrease the biotransformation of the peptides. The modified cupredoxin derived peptides can be used in methods to treat mammals for cancer, conditions related to inappropriate angiogenesis, viral and bacterial infections, and specifically HIV and malaria, conditions related to ephrin signaling, and to deliver cargo compounds, including diagnostic compounds, to cancer cell | 11-19-2009 |
| 20100008919 | COMPOSITIONS AND METHODS TO CONTROL ANGIOGENESIS WITH CUPREDOXINS - The present invention relates to compositions comprising cupredoxins, and their use to inhibit angiogenesis in mammalian cells, tissues, and animals, and particularly the angiogenesis that accompanies tumor development and particularly in humans. Specifically, the present invention relates to compositions comprising the cupredoxin(s), and or peptides that are variants, derivatives or structural equivalents of cupredoxins, which retain the ability to inhibit angiogenesis in mammalian cells, tissues or animals. These compositions may be peptides or pharmaceutical compositions, among others. The compositions of the invention may be used to treat any pathological condition that has as a symptom or cause, inappropriate angiogenesis, and particularly inappropriate angiogenesis related to tumor development. | 01-14-2010 |
| 20100093057 | COMPOSITIONS AND METHODS TO PREVENT CANCER BY STABILIZING P53 THROUGH NON MDM2-MEDIATED PATHWAYS - The present invention relates to compositions and methods comprising chemopreventive agents that may be cupredoxin(s) or variants, derivatives and structural equivalents of cupredoxins, and at least one other chemopreventive agent. Specifically, these compositions may comprise azurin from | 04-15-2010 |
David Beattie, Belmont, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100261752 | 5-HT4 RECEPTOR AGONIST COMPOUNDS FOR TREATMENT OF COGNITIVE DISORDERS - The invention provides methods for the treatment of cognitive disorders utilizing specific 5-HT | 10-14-2010 |
Douglas D. Beattie, Sudbury, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090133118 | METHODS AND SYSTEMS FOR AUTOMATED AUTHENTICATION, PROCESSING AND ISSUANCE OF DIGITAL CERTIFICATES - A computer system and process for issuing digital certificates use domain-control vetting to issue certificates. A requestor requests a certificate from a certificate authority, which identifies at least one approver to approve issuance of the digital certificate. If approved, the certificate authority accepts the request, creates and signs the certificate, and the signed certificate is sent to the requester. | 05-21-2009 |
Gillian Beattie, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090155218 | COMPOSITIONS AND METHODS FOR GROWTH OF EMBRYONIC STEM CELLS - The present invention relates to methods, compositions, and kits for maintenance of the undifferentiated state and/or pluripotency in stem cells, including embryonic stem (ES) cells. It also relates to stem cells that have been maintained in an undifferentiated state. The present invention provides these aspects using culture medium enriched with a TGFβ family member protein, an FGF family member protein, and/or nicotinamide, without using fibroblast feeder layers, conditioned media, or leukemia inhibitory factor. | 06-18-2009 |
Irene Beattie, Leander, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20080225566 | Using eFuses to Store PLL Configuration Data - A mechanism for using electrical fuses (eFuses) to store phase-locked loop (PLL) configuration data are provided. With the mechanism, a portion of the eFuses present in the integrated circuit are reserved for the PLL configuration data. Upon power up, a power up controller and eFuse controller direct the sensing and serial transfer of the data in the portion of eFuses to the PLL under the reference clock. When the transfer is complete, the power up controller directs the PLL logic to load the configuration data and start. The mechanism of the present invention allows manufacturing to tailor the PLL configuration on a given device based on the characteristics of that device and its intended usage. Thus, the same PLL may be used in the same or different architectures to perform different operations based on the configuration data passed into the PLL from the eFuses. | 09-18-2008 |
James Beattie, San Ramon, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100205541 | SOCIAL NETWORK DRIVEN INDEXING SYSTEM FOR INSTANTLY CLUSTERING PEOPLE WITH CONCURRENT FOCUS ON SAME TOPIC INTO ON-TOPIC CHAT ROOMS AND/OR FOR GENERATING ON-TOPIC SEARCH RESULTS TAILORED TO USER PREFERENCES REGARDING TOPIC - A machine-implemented social networking system builds up and repeatedly refreshes a hierarchy tree containing topic nodes. New nodes are added as new topics emerge in online public forums. Each topic node can link to an on-topic real time chat room whose occupants are currently discussing the topic of the node. A chat room can be pointed to by more than one node if the room is discussing multiple topics. Rooms can migrate from node to node as room topic dynamically changes. A system user who explicitly or inferentially wishes to be invited into a chat room which is on-topic with what the user is currently focused upon can do so by use of a node-seeking automated process. The process operates in the background and seeks out nodes of the hierarchy tree that currently have topics appearing to be the same as or similar to what topics the user appears to have in mind. Content browsing experience of the user is enhanced by addition of an invitations displaying subsystem that automatically invites him or her to co-compatible chat rooms currently discussing the topic(s) the user appears to have in mind. One of the many topics that a user may inferentially have in mind is that of being at a given location as reported by the user's GPS and wondering what best to do at that location and time. | 08-12-2010 |
James C. Beattie, Baltimore, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20080318694 | Automatic transmission and shaft system therefor - A shaft system for an automatic transmission includes a stator support shaft having an internal axial bore for receiving an input shaft, a forward engagement portion for engaging a stator of a torque converter of the automatic transmission and an integral stator support flange extending radially outward for engaging a stator support of the automatic transmission and transferring to the stator support substantially all of a torque load imposed on the stator support shaft by the stator. The stator support flange includes at least one oil flow bore positioned therein to supply oil between different components of the transmission. | 12-25-2008 |
James Gordon Beattie, Bergenfield, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090319656 | APPARATUS AND METHOD FOR MANAGING A NETWORK - A system that incorporates teachings of the present disclosure may include, for example, a server having a controller to perform a first query of a network device by way of a wired connection with the network device, perform a second query of the network device by way of a wireless connection with the network device, detect an undesired condition associated with at least one of the network device and the wired connection with the network device based at least in part on the first and second queries, and discern between the undesired condition being associated with the network device and being associated with the wired connection based at least in part on the first and second queries. Other embodiments are disclosed. | 12-24-2009 |
| 20100115605 | METHODS AND APPARATUS TO DELIVER MEDIA CONTENT ACROSS FOREIGN NETWORKS - Example methods and apparatus to deliver media content across foreign networks are disclosed. A disclosed example method includes receiving a request from a subscriber of a media provider, the media provider associated with a native network and identifying a foreign network associated with a current location of the subscriber. The example method also includes identifying at least one quality of service (QoS) parameter associated with the foreign network, comparing the at least one foreign network QoS parameter with a first threshold value, and at least one of prohibiting a service delivered by the media provider when the at least one foreign network QoS parameter fails to meet the first threshold value, or enabling the service when the at least one foreign network QoS parameter meets the first threshold value. | 05-06-2010 |
| 20110122246 | APPARATUS AND METHOD FOR PROVIDING A SURVEILLANCE SYSTEM - A system that incorporates teachings of the present disclosure may include, for example, a media processor having a controller to receive media content from a content provider operating in an interactive television (iTV) network, wherein the media content is associated with a plurality of channels, wherein the media content comprises audio and video content, change each channel of the plurality of channels based on a time interval provided by a monitoring system, analyze audio content of the media content for each channel for detecting an undesired condition associated with the video content, wherein the audio content is encoded by an iTV audio encoder, and transmit the media content to the monitoring system if the undesired condition is detected, the media content being transmitted for analysis by the monitoring system and for creation of a trouble ticket if a qualitative threshold for the media content is determined to not be satisfied. Other embodiments are disclosed. | 05-26-2011 |
Jeffrey S. Beattie, West Hartford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100040460 | Platforms with Curved Side Edges and Gas Turbine Engine Systems Involving Such Platforms - Platforms with curved side edges and gas turbine engine systems involving such platforms are provided. In this regard, a representative airfoil assembly for a gas turbine engine includes: a platform having a gas path side, a non-gas path side, a leading edge, a trailing edge, a first side edge extending between the leading edge and the trailing edge and exhibiting a first curve along a length thereof, and a second side edge extending between the leading edge and the trailing edge and exhibiting a second curve along a length thereof; and an airfoil extending from the gas path side of the platform; the platform and the airfoil exhibiting a unitary construction such that a continuous exterior surface blends from the airfoil to the platform. | 02-18-2010 |
| 20100040479 | Gas Turbine Engine Systems Involving Baffle Assemblies - Gas turbine engine systems involving baffle assemblies are provided. In this regard, a representative baffle assembly for a gas turbine engine includes: a cooling plenum defining a cooling air path; and a baffle sized and shaped to extend between surfaces of the cooling plenum such that a cooling air path of reduced cross-section is formed between the baffle and the surfaces, the baffle being operative to increase a flow rate of cooling air as the cooling air directed to the cooling air path is redirected through the cooling air path of reduced cross-section. | 02-18-2010 |
Jeffrey S. Beattie, South Glastonbury, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110123310 | TURBINE AIRFOIL PLATFORM COOLING CORE - A gas turbine engine component has a platform and an airfoil extending from the platform. The platform has a pressure side and a suction side. A cooling passage is formed within the platform, and extends along a pressure side of the platform. Air leaves the passage through an air outlet on a suction side of the platform. | 05-26-2011 |
Jodi Beattie, Wentzville, MO US
| Patent application number | Description | Published |
|---|---|---|
| 20110262397 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR CONTROL OF HEPATITIS C VIRAL INFECTIONS - Various tetrahydropyrazolo[1,5-a]pyrimidine compounds, compositions, methods of making, and methods for the prevention and treatment of HCV infections and associated diseases are disclosed. The invention further relates to biomarkers for identification of HCV strains which are resistant to the tetrahydropyrazolo[1,5-a]pyrimidine compounds. | 10-27-2011 |
Kenneth L. Beattie, Crossville, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20090305230 | Real Time Detection of Molecules, Cells and Particles Using Photonic Bandgap Structures - Provided herein is a photonic bandgap (PBG) detector effective to detect inorganic molecules, organic biomolecules or biopolymers, cells, subcellular organelles, and particles. The PBG detector utilizes photonic crystals having a binding agent attached to channel surfaces comprising the crystals to selectively bind a molecule, cell or particle of interest so that an increase in light transmission is detectably induced within the photonic bandgap upon binding. Also provided are methods of optically detectiing an analyte and of identifying the presence of a cell or a particle in a biological sample. | 12-10-2009 |
| 20110105346 | Universal fingerprinting chips and uses thereof - The present invention discloses a designing strategy for constructing a set of probes useful for analyzing all or most prokaryotic and eukaryotic genomes. A set of capture probes with optimal fingerprinting properties and highly representative of all possible sequences of an organism can be selected by six sequential steps. Fingerprinting potential of such probes is validated by phylogenetic analysis, which generates results that strongly correlate with phylogenetic trees produced by sequence alignment. The probes generated by the instant methods can be used for detecting an organism, for establishing phylogenetic relationships between different organisms, for detection of single nucleotide polymorphisms and a wide variety of other applications that require genetic analysis. | 05-05-2011 |
Mark S. Beattie, Katy, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20110026362 | Telemetry Coding and Surface Detection for a Mud Pulser - A method for encoding a non-negative integer, for example, representative of MWD/LWD data, includes encoding at least a portion of the integer using at least a first order Fibonacci derived sequence. The remainder of the integer may be encoded using conventional Fibonacci encoding. The invention tends to improve coding efficiency, downhole and surface synchronization, and surface detection. | 02-03-2011 |
Russell Beattie, Menlo Park, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080256170 | SOCIAL NETWORKING FOR MOBILE DEVICES - A mobile device, system, and method are directed towards enabling an integrated display of live views. The integrated live views are generated by employing social networking information, including moods of a person, avatars, status of a member's activities including whether they are in an IM session, or the like. Integrated live views may include a live contact list, a group view, a friend view, an activity oriented view, a list of content, or the like, based on the mobile user's social networking information. By providing the mobile user with integrated live views of their social network, the mobile user may be able communicate with other members within the mobile social networking context, to obtain, and respond to invites from a social network member, provide opportunities for activities to other members, to grow their social network, and to consume content that is displayed relative to their social network. | 10-16-2008 |