Patent application number | Description | Published |
20080228191 | Femoral elevator - A bone retractor that may be used as a femoral elevator. The bone retractor includes a clamp for attaching the bone retractor to an operating room bed rail, a post attached to the clamp via a hinged joint, a mount slidably attached to the post and a hook coupled to the mount which in turn is attached to the post. A shaft passes through the interior of the post and attaches to clamp. The clamp has a lower jaw and an upper jaw. An opening is formed in the lower jaw and an end of the shaft is engaged in the opening. The shaft has two sections with a universal joint connecting these two sections. The born retractor is attached to the operating room bed rail by applying clamp to the bed rail. With bone retractor attached to the bed rail, the post is lowered towards the wound. The hook is placed under the bone, and the bone exposed by holding the hook or the post and lifting the bone out of the wound. A knob is tightened to lock the post and consequently the hook in the raised position while the surgeon performs the surgery. When the surgeon is ready, the bone is lowered in the wound by loosening the knob and slowly placing the bone in the desired position in the wound. | 09-18-2008 |
20100160914 | SINGLE USE RESECTION GUIDE - Single use or disposable cutting blocks and methods for utilizing same are disclosed. The blocks are preferably constructed of polymer and/or other suitable low cost and light weight materials. The blocks may be adapted for use with low friction cutting instruments, as well as other such cutting instruments. Several differently sized and configured blocks may be utilized to perform a single surgical procedure. In addition, kits housing one or more such blocks, with or without other instruments are possible. | 06-24-2010 |
20110160734 | COMPOUND OFFSET HANDLE - A method for preparing a proximal femoral canal of a patient during total hip replacement surgery uses a shaping instrument or broach having a proximal portion with an anterior surface, and a posterior surface, each surface being spaced apart from a medial-lateral plane through the shaping instrument. A handle portion having a proximal portion having a first longitudinal axis is connected to a transition portion having a second longitudinal axis and a distal portion having a third longitudinal axis. Wherein the handle comprises a dual offset including a first compound bend between the transition portion and the proximal portion and wherein, when following a direction from the transition portion to the proximal portion, the first compound bend includes a bend in the posterior direction and a bend in the lateral direction, and wherein the first compound bend is less than 90 degrees. No plane extending through the proximal portion is coplanar with a plane extending through both the transition portion and the distal portion. | 06-30-2011 |
20110313424 | PATIENT-SPECIFIC TOTAL HIP ARTHROPLASTY - Disclosed herein are systems and methods for performing total hip arthroplasty with patient-specific guides Pre-operative images of a pelvic region of a patient are taken in order to predefine the structure of the guides and corresponding implants. From the obtained image data an insertional vector for implanting an acetabular implant or component into an acetabulum of the patient is determined, wherein the insertional vector is coaxial with a polar axis of the acetabular component. Also from the obtained image data, a superior surface of the guides and implants can be shaped to match the acetabulum of the patient. A nub portion extending outwardly from the superior surface of the guides and implants is shaped to substantially match the shape of a fovea of the acetabulum. A guide portion of the guides forming a slot has a longitudinal axis coaxial with the determined insertional vector of a corresponding acetabular component. | 12-22-2011 |
20130090657 | COMPOUND OFFSET HANDLE - A method for preparing a proximal femoral canal of a patient during total hip replacement surgery uses an instrument having a handle, a shaping member including structure configured to shape bone, wherein the structure configured to shape bone comprises at least two cutting surfaces on opposite sides of the shaping member, and a connecting member connecting the handle and the shaping member, the connecting member having a plurality of transverse cross sections. The connecting member includes a dual offset including a first compound bend between the connecting member and the handle, wherein when following a direction from the connecting member to the handle, the first compound bend includes a bend in a posterior direction and a bend in a lateral direction. The connecting member also includes a second compound bend between the connecting member and the shaping member, the second compound bend in an anterior and a medial direction. | 04-11-2013 |
20130197866 | METHOD FOR DESIGNING A BONE MORPHOLOGY BASED HIP SYSTEM - A method of designing a group of femoral implants from three-dimensional images of femurs from a patient population greater than 100. A boundary between cortical and cancellous bone is defined in each of the images. A longitudinal axis of the femur is defined centered within the boundary. The width of the boundary is measured in a direction perpendicular to the axis at multiple cross-sections along the longitudinal axis spaced less than 20 mm. At least five (5) different size implants for implantation in a noncortical bone area of the femur are designed based on the measured widths. At least one area of the proximal femoral component boundary is designed where the implant outer surface is sized to be within 2 mm of the cortical bone. The proximal dimensions of the at least five implants are sized to provide the fit within 2 mm in 95% of the femurs from the population. | 08-01-2013 |
20130289566 | COMPOUND OFFSET HANDLE - A method for preparing a proximal femoral canal of a patient during total hip replacement surgery uses an instrument having a handle, a shaping member including structure configured to shape bone, wherein the structure configured to shape bone comprises at least two cutting surfaces on opposite sides of the shaping member, and a connecting member connecting the handle and the shaping member, the connecting member having a plurality of transverse cross sections. The connecting member includes a dual offset including a first compound bend between the connecting member and the handle, wherein when following a direction from the connecting member to the handle, the first compound bend includes a bend in a posterior direction and a bend in a lateral direction. The connecting member also includes a second compound bend between the connecting member and the shaping member, the second compound bend in an anterior and a medial direction. | 10-31-2013 |
20150105784 | PATIENT-SPECIFIC TOTAL HIP ARTHROPLASTY - Disclosed herein are systems and methods for performing total hip arthroplasty with patient-specific guides Pre-operative images of a pelvic region of a patient are taken in order to predefine the structure of the guides and corresponding implants. From the obtained image data an insertional vector for implanting an acetabular implant or component into an acetabulum of the patient is determined, wherein the insertional vector is coaxial with a polar axis of the acetabular component. Also from the obtained image data, a superior surface of the guides and implants can be shaped to match the acetabulum of the patient. A nub portion extending outwardly from the superior surface of the guides and implants is shaped to substantially match the shape of a fovea of the acetabulum. A guide portion of the guides forming a slot has a longitudinal axis coaxial with the determined insertional vector of a corresponding acetabular component. | 04-16-2015 |
20150133945 | HANDHELD TRACKING SYSTEM AND DEVICES FOR ALIGNING IMPLANT SYSTEMS DURING SURGERY - The present invention discloses handheld tracking systems and devices comprising of at least one handheld tracking device for intra-operative aligning or positioning of surgical implant systems and instruments with reference to the anatomy of a patient. The handheld tracking system further comprises of at least one trackable element. The handheld device is mounted at the proposed implantation site using the holding means while trackable element(s) is/are mounted at predetermined location(s) such that data from said deployed trackable element(s) relating to the position of the patient and the surgical instruments are input continuously into the handheld devices. The handheld device then processes the data on the basis of pre-loaded preoperative scanned images in the processing means to monitor the accurate placement of said implant system onsite in sterile environment. | 05-14-2015 |
Patent application number | Description | Published |
20090157071 | System and Method for Tissue Sealing - An electrosurgical system is disclosed. The electrosurgical system includes an electrosurgical generator adapted to supply electrosurgical energy to tissue. The electrosurgical generator includes impedance sensing circuitry which measures impedance of tissue, a processor configured to determine whether a tissue reaction has occurred as a function of a minimum impedance value and a predetermined rise in impedance, wherein tissue reaction corresponds to a boiling point of tissue fluid, and an electrosurgical instrument including at least one active electrode adapted to apply electrosurgical energy to tissue. A tissue cooling period is provided to enhance operative outcomes. | 06-18-2009 |
20090157072 | System and Method for Tissue Sealing - An electrosurgical system is disclosed. The electrosurgical system includes an electrosurgical generator adapted to supply electrosurgical energy to tissue. The electrosurgical generator includes impedance sensing circuitry which measures impedance of tissue, a processor configured to determine whether a tissue reaction has occurred as a function of a minimum impedance value and a predetermined rise in impedance, wherein tissue reaction corresponds to a boiling point of tissue fluid, and an electrosurgical instrument including at least one active electrode adapted to apply electrosurgical energy to tissue. A tissue cooling period is provided to enhance operative outcomes. | 06-18-2009 |
20090157075 | System and Method for Tissue Sealing - An electrosurgical system is disclosed. The electrosurgical system includes an electrosurgical generator adapted to supply electrosurgical energy to tissue. The electrosurgical generator includes impedance sensing circuitry which measures impedance of tissue, a processor configured to determine whether a tissue reaction has occurred as a function of a minimum impedance value and a predetermined rise in impedance, wherein tissue reaction corresponds to a boiling point of tissue fluid, and an electrosurgical instrument including at least one active electrode adapted to apply electrosurgical energy to tissue. A tissue cooling period is provided to enhance operative outcomes. | 06-18-2009 |
20110060335 | Apparatus for Tissue Fusion and Method of Use - An end effector for an electrosurgical forceps is provided. The end effector includes a first jaw member having proximal and distal ends and a second jaw member having proximal and distal ends. The distal end of the first jaw member includes a recess defined therein. The distal end of the second jaw member includes a first prong configured for receipt within the recess defined in the first jaw member. Wherein engagement of the first prong of the second jaw member within the recess of the first jaw member creates a gap between the first and second jaw members to enable tissue sealing. | 03-10-2011 |
Patent application number | Description | Published |
20100246401 | Congestion Management in a Shared Network - A shared channel used to communicate between a cable modem termination system and multiple cable modems is managed to prevent and/or reduce the impact of congestion. If the average channel utilization is above a near-congestion threshold, a cable modem in an extended high consumption state is assigned a reduced data transmission priority for managed traffic. Priority for that cable modem is restored to a default preferred level when the channel usage by that cable modem drops below a predetermined level or when the average aggregate channel utilization by all cable modems drops below the near-congestion threshold. | 09-30-2010 |
20100246582 | Subscriber Access Network Achitecture - A subscriber network architecture includes a packet processing node that communicates with a network backbone and with a plurality of access nodes. The access nodes also communicate with a plurality of subscriber devices. The packet processing node controls Quality of Service (QoS) levels for the subscriber devices, routes user data to subscriber devices based on downstream communication channels of the access nodes and QoS levels, and receives data from subscriber devices (via the access nodes) for forwarding across the network backbone. | 09-30-2010 |
20120075997 | Subscriber Access Network Architecture - A subscriber network architecture includes a packet processing node that communicates with a network backbone and with a plurality of access nodes. The access nodes also communicate with a plurality of subscriber devices. The packet processing node controls Quality of Service (QoS) levels for the subscriber devices, routes user data to subscriber devices based on downstream communication channels of the access nodes and QoS levels, and receives data from subscriber devices (via the access nodes) for forwarding across the network backbone. | 03-29-2012 |
20120120807 | Congestion Management In A Shared Network - A shared channel used to communicate between a cable modem termination system and multiple cable modems is managed to prevent and/or reduce the impact of congestion. If the average channel utilization is above a near-congestion threshold, a cable modem in an extended high consumption state is assigned a reduced data transmission priority for managed traffic. Priority for that cable modem is restored to a default preferred level when the channel usage by that cable modem drops below a predetermined level or when the average aggregate channel utilization by all cable modems drops below the near-congestion threshold. | 05-17-2012 |
20130046863 | Prioritizing Local and Network Traffic - According to some aspects as described herein, a user may purchase or otherwise be provided with an accelerated service for selected software applications, devices, and/or ports to experience a high level of communication. The accelerated service may be created, for example, by using a dedicated network data flow such that the user's customer premise equipment (CPE) network access device may put priority traffic in a different upstream data flow than the commonly shared flow, which may involve tagging the traffic upstream to the network with a priority indicator such as a flow identifier. Based on similar factors, the user may also control local priority of data received downstream from the network for distribution to one or more local devices. | 02-21-2013 |
20150229561 | Prioritizing Local and Network Traffic - According to some aspects as described herein, a user may purchase or otherwise be provided with an accelerated service for selected software applications, devices, and/or ports to experience a high level of communication. The accelerated service may be created, for example, by using a dedicated network data flow such that the user's customer premise equipment (CPE) network access device may put priority traffic in a different upstream data flow than the commonly shared flow, which may involve tagging the traffic upstream to the network with a priority indicator such as a flow identifier. Based on similar factors, the user may also control local priority of data received downstream from the network for distribution to one or more local devices. | 08-13-2015 |
Patent application number | Description | Published |
20090042770 | Branched Chain Amino Acid Chelate - Compositions are disclosed comprising mineral/branched-chain amino acid chelates such as, for example, calcium leucinate, for increasing absorption of the branched-amino acid in a human or animal subject. Methods are also provided for using the compositions to increase branched-chain amino acid absorption to increase or maintain muscle mass in athletes or in individuals having diseases such as ALS, muscular dystrophy, sarcopenia associated with aging, or muscle atrophy associated with spinal cord injury, as well as to decrease mental fatigue. | 02-12-2009 |
20090264363 | Leucine-Rich Peptide Compositions and Methods for Isolation - Disclosed are compositions comprising isolated peptides having a leucine content of from about 12 to about 40 weight percent. Also disclosed is a method for isolating leucine-rich peptides from protein sources such as bovine whey and methods of use for these peptides to provide beneficial effects in a human and/or animal such as increasing blood flow, decreasing blood pressure, increasing muscle mass, improving cognitive function, improving cardiovascular function, etc. | 10-22-2009 |
20130029027 | Pet Food Composition - Disclosed is a composition and method which facilitate increased incorporation of meat into a dry food product, such as an extruded pet food kibble. Products made by incorporating the composition provide increased resistance to breakage, excellent palatability, and increased nutritional value. | 01-31-2013 |
20140171378 | Leucine-Rich Peptide Compositions and Methods for Isolation - Disclosed are compositions comprising isolated peptides having a leucine content of from about 12 to about 40 weight percent. Also disclosed is a method for isolating leucine-rich peptides from protein sources such as bovine whey and methods of use for these peptides to provide beneficial effects in a human and/or animal such as increasing blood flow, decreasing blood pressure, increasing muscle mass, improving cognitive function, improving cardiovascular function, etc. | 06-19-2014 |
20140349003 | Acidified Whey Protein Compositions and Methods for Making Them - Embodiments of the invention relate to whey protein compositions that can be incorporated into food or beverage products that provide supplemental amounts of protein. The acidified whey protein compositions of the present invention may comprise a liquid whey protein and an acidulant. The liquid whey protein and the acidulant may be blended, and the resulting composition may then be co-dried. The acidulant may be present in an amount effective for reducing the pH of the composition prior to drying to a value less than about 6. Embodiments of the present invention also include methods of preparing co-dried acidified whey protein compositions exhibiting improved organoleptic characteristics. | 11-27-2014 |
Patent application number | Description | Published |
20080273999 | Machine for compressing gasses and refrigerant vapors - A machine for compressing gases and vapors includes a housing base containing an internal raceway, a spinning rotor containing a plurality of hollow cylinders, a plurality of spherical balls serving as positive displacement pistons which roll atop a housing base raceway and which reciprocate within the rotor cylinders, a static center rod containing intake and exhaust ports and a plurality of magnets providing rotational torque to the rotor, which are driven by an AC or DC motor during operation. A preferred embodiment includes the step(s) of gas or vapor intake, compression and exhaust within each rotor cylinder through a cycle during which the ball pistons reciprocate into and out of each cylinder while rolling atop the housing raceway. A preferred embodiment includes compression of gas and vapor occurring quietly, efficiently, with low mechanical vibration and in any physical orientation of the machine. | 11-06-2008 |
20100097767 | Machine for passively removing heat generated by an electronic circuit board - A machine for passively removing heat generated by an electronic circuit board is disclosed. In a typical embodiment an electronic circuit board of any type or size is comprised of electronic components producing heat during operation. High thermal conductivity moldable pads applied to both sides of the electronic circuit board form a conductive pathway to transport heat away from electronic circuits and components. A two piece rigid heat sink having thin rigid conductive fins on its top base is coupled together forming a cavity into which the computer board/conductive pad assembly fits, thereby forming a second conductive pathway for heat transport away from board features. The thin rigid conductive fins collectively form yet a third conductive pathway for heat transport from the solid base of the two piece rigid heat sink. Exposure of the thin rigid conductive fins to cooler surrounding air provides convective transfer of heat from the fins to ambient air. | 04-22-2010 |
20140070018 | DEVICE AND METHOD FOR AEROSOL DISPENSING OF A PLURALITY OF DRY POWDERS AND NANO-MATERIALS - The present invention is a powder aerosol device that includes a cylindrical vessel, a nozzle that disperses by aerosol a plurality of dry powders and nano-materials contained in the cylindrical vessel and a propellant chamber that contains a propellant. The device also includes a cylinder that contains the plurality of dry powders and nano-materials dispersed by the aerosol to ambient, a piston held within the cylinder that moves the piston to push the plurality of dry powders and nano-materials toward the nozzle and a plurality of apertures disposed on the piston where propellant stream is passed through the plurality of apertures which fluidizes the plurality of dry powders and nano-materials. The present invention also includes a method for aerosol dispensing of a plurality of dry powders and nano-materials with a powder aerosol device. | 03-13-2014 |
20160091255 | ROTARY HIGH DENSITY HEAT EXCHANGER - The present invention relates generally to the rotary high density heat exchangers. In one embodiment, the present invention relates to rotary high density heat exchangers that contain one or more fan blades where each fan blade contains heat exchanging surfaces on the surface thereof. | 03-31-2016 |
Patent application number | Description | Published |
20140025427 | INFERRING AND SUGGESTING ATTRIBUTE VALUES FOR A SOCIAL NETWORKING SERVICE - Disclosed in some examples is a method of inferring one or more attribute values of a member of a social networking service by collecting a plurality of attribute values associated with attributes of a plurality of members of a social networking service, the plurality of attribute values including member profile information; and inferring one or more attribute values regarding a particular member in the plurality of members based upon the collected plurality of attribute values and a plurality of collected attribute values of the particular member. | 01-23-2014 |
20150095121 | METHODS AND SYSTEMS FOR RECOMMENDING DECISION MAKERS IN AN ORGANIZATION - This disclosure provides for systems and methods directed to generating colleague recommendations within a social network service. The systems and methods may include identifying a sample member of a social network service and determining an organizational unit associated with the sample member. The sample member may be associated with prior member activity involving a source member and the organizational unit may represent a department within an organization. The systems and methods may also include identifying various candidate members, where the candidate members are associated with the organizational unit. The systems and methods may also include surfacing the plurality of candidate members to a computer system being operated by the source member. | 04-02-2015 |
20150261759 | QUERYING OF REPUTATION SCORES IN REPUTATION SYSTEMS - The disclosed embodiments provide a reputation system. The reputation system includes a ranking apparatus that obtains a set of reputation scores for one or more dimensions of a set of items in the reputation system and generates a ranking of the items based on the reputation scores and the one or more quantiles. The reputation system also includes a query-processing apparatus that obtains a query comprising the one or more dimensions and one or more quantiles associated with the one or more dimensions and provides the ranking in a response to the query. | 09-17-2015 |
20150262081 | ESTIMATING REPUTATION SCORES IN REPUTATION SYSTEMS - The disclosed embodiments provide a reputation system. The reputation system includes a statistical model associated with a set of items and a set of dimensions of the items in the reputation system, wherein the statistical model is trained using a positive class and a negative class. The reputation system also includes a scoring apparatus that applies the statistical model to a set of features for each of the items to estimate a set of reputation scores for the items. Finally, the reputation system includes a ranking apparatus that enables use of the set of reputation scores in the reputation system. | 09-17-2015 |
Patent application number | Description | Published |
20100143997 | ENGINEERED MICROORGANISMS CAPABLE OF PRODUCING TARGET COMPOUNDS UNDER ANAEROBIC CONDITIONS - The present invention is generally provides recombinant microorganisms comprising engineered metabolic pathways capable of producing C3-C5 alcohols under aerobic and anaerobic conditions. The invention further provides ketol-acid reductoisomerase enzymes which have been mutated or modified to increase their NADH-dependent activity or to switch the cofactor preference from NADPH to NADH and are expressed in the modified microorganisms. In addition, the invention provides isobutyraldehyde dehydrogenase enzymes expressed in modified microorganisms. Also provided are methods of producing beneficial metabolites under aerobic and anaerobic conditions by contacting a suitable substrate with the modified microorganisms of the present invention. | 06-10-2010 |
20110201072 | Modified alcohol dehydrogenases for the production of fuels and chemicals - The present invention relates to recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial metabolites. In various aspects of the invention, the recombinant microorganisms may further comprise one or more modifications resulting in the reduction or elimination of 3 keto-acid (e.g., acetolactate and 2-aceto-2-hydroxybutyrate) and/or aldehyde-derived by-products. In various embodiments described herein, the recombinant microorganisms may be microorganisms of the | 08-18-2011 |
20120028324 | ENGINEERED MICROORGANISMS CAPABLE OF PRODUCING TARGET COMPOUNDS UNDER ANAEROBIC CONDITIONS - The present invention is generlly provides recombinant microorganisms comprising engineered metabolic pathways capable of producing C3-C5 alcohols under aerobic and anaerobic conditions. The invention further provides ketol-acid reductoisomerase enzymes which have been mutated or modified to increase their NADH-dependent activity or to switch the cofactor preference from NADPH to NADH and are expressed in the modified microorganisms. In addition, the invention provides isobutyraldehyde dehydrogenase enzymes expressed in modified microorganisms. Also provided are methods of producing beneficial metabolites under aerobic and anaerobic conditions by contacting a suitable substrate with the modified microorganisms of the present invention. | 02-02-2012 |
20120058532 | ENGINEERED MICROORGANISMS CAPABLE OF PRODUCING TARGET COMPOUNDS UNDER ANAEROBIC CONDITIONS - The present invention is generally provides recombinant microorganisms comprising engineered metabolic pathways capable of producing C3-C5 alcohols under aerobic and anaerobic conditions. The invention further provides ketol-acid reductoisomerase enzymes which have been mutated or modified to increase their NADH-dependent activity or to switch the cofactor preference from NADPH to NADH and are expressed in the modified microorganisms. In addition, the invention provides isobutyraldehyde dehydrogenase enzymes expressed in modified microorganisms. Also provided are methods of producing beneficial metabolites under aerobic and anaerobic conditions by contacting a suitable substrate with the modified microorganisms of the present invention. | 03-08-2012 |
20120190089 | ENGINEERED MICROOGRANISMS CAPABLE OF PRODUCING TARGET COMPOUNDS UNDER ANAEROBIC CONDITIONS - The present invention is generally provides recombinant microorganisms comprising engineered metabolic pathways capable of producing C3-C5 alcohols under aerobic and anaerobic conditions. The invention further provides ketol-acid reductoisomerase enzymes which have been mutated or modified to increase their NADH-dependent activity or to switch the cofactor preference from NADPH to NADH and are expressed in the modified microorganisms. In addition, the invention provides isobutyraldehyde dehydrogenase enzymes expressed in modified microorganisms. Also provided are methods of producing beneficial metabolites under aerobic and anaerobic conditions by contacting a suitable substrate with the modified microorganisms of the present invention. | 07-26-2012 |
20140017748 | MODIFIED ALCOHOL DEHYDROGENASES FOR THE PRODUCTION OF FUELS AND CHEMICALS - The present invention relates to recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial metabolites. In various aspects of the invention, the recombinant microorganisms may further comprise one or more modifications resulting in the reduction or elimination of 3 keto-acid (e.g., acetolactate and 2-aceto-2-hydroxybutyrate) and/or aldehyde-derived by-products. In various embodiments described herein, the recombinant microorganisms may be microorganisms of the | 01-16-2014 |
20140295512 | Ketol-Acid Reductoisomerases With Improved Performance Properties - The present invention relates to recombinant microorganisms comprising at least one nucleic acid molecule encoding a ketol-acid reductoisomerase (KARI) or modified NADH-dependent variant thereof, wherein said KARI is at least about 60% identical to SEQ ID NO: 2. In various aspects of the invention, the recombinant microorganisms may comprise an isobutanol producing metabolic pathway and can be used in methods of making isobutanol. | 10-02-2014 |
20140295513 | High-Performance Ketol-Acid Reductoisomerases - The present invention relates to recombinant microorganisms comprising at least one nucleic acid molecule encoding a ketol-acid reductoisomerase (KARI) or a modified NADH-dependent variant thereof, wherein said KARI is at least about 80% identical to SEQ ID NO: 2, SEQ ID NO: 4, SEQ ID NO: 6, SEQ ID NO: 8, SEQ ID NO: 10, SEQ ID NO: 28, SEQ ID NO: 40, or SEQ ID NO: 58. The present invention also relates to recombinant microorganisms comprising at least one nucleic acid molecule encoding a ketol-acid reductoisomerase (KARI) or a modified NADH-dependent variant thereof, wherein said KARI is at least about 99% identical to SEQ ID NO: 64. In various aspects of the invention, the recombinant microorganisms may comprise an isobutanol producing metabolic pathway and can be used in methods of making isobutanol. | 10-02-2014 |