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Basler
Christopher Basler, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090028901 | Screening methods for identifying viral proteins with interferon antagonizing functions and potential antiviral agents - The present invention relates, in general, to a screening method for identifying novel viral proteins with interferon antagonizing function using a transfection-based assay, and the use of such proteins in isolating various types of attenuated viruses for the development of vaccine and pharmaceutical formulations. The invention also relates to the use of viral interferon antagonists in screening assays to identify potential anti-viral agents. The invention further relates to protocols utilizing interferon antagonists, e.g., NS1, to enhance gene therapy or DNA vaccination based on their ability to increase gene expression. | 01-29-2009 |
Christopher F. Basler, Hastings On Hudson, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20120100142 | MONOCLONAL ANTIBODIES TO INFLUENZA H1N1 VIRUS USES THEREOF - The present invention is directed to particular monoclonal antibodies and fragments thereof that find use in the detection, prevention and treatment of influenza virus infections. In particular, these antibodies may neutralize or limit the replication of H1N1 influenza virus. Also disclosed are improved methods for producing such monoclonal antibodies. | 04-26-2012 |
Hermann Basler, Alberta CA
| Patent application number | Description | Published |
|---|---|---|
| 20100175892 | GUIDE TUBE FOR CONTINUOUS ROD - A guide tube for continuous rod has a sections pivotably connected together by at least one translatable pivot. The tube connects to a rig at a fixed pivot and is initially folded on the rig for transport. To unfold and raise the tube for operation, a rig operator pivots a support rod pivotably connected to the tube away from the rig using a rope. This pivoting support rod moves the attachment point of a winchline extending from the rig to the rod beyond the tube's fixed pivot. Also, the pivoting rod tensions a sling having a fixed length that extends from the rod to the tube's translatable pivot. In this way, the winchline can be tensioned without the need for rig operators to perform a substantial amount of manual labor as conventionally done. Once the outer sections of the guide tube are lowered to the ground, the entire guide tube can be unfolded and raised with the tensioned winchline. | 07-15-2010 |
| 20110072874 | Continuous Rod Transport System - A transport system has a dedicated trailer for transporting a small transport reel (i.e., <18-ft in diameter) of continuous rod to the field. The trailer has a pedestal that can pivot the reel. A hub motor on the pedestal can turn the reel, and a transfer unit and rod bender on the trailer can curve or straighten the rod when being fed into or out of the reel. A power and hydraulic system operates the various hydraulic components on the trailer. In other aspects, the transport system includes stands that can hold the small transport reels on a trailer within a defined transport envelope. When empty, these stands can be stacked on top of one another on the trailer for return to a facility. | 03-31-2011 |
| 20110073552 | Continuous Rod Transport System - A continuous rod transport system has a reel with a cage and a removable hub. The cage has support members interconnected by rings to hold the rod coiled in the cage. The removable hub has extending arms that removably attach to the cage's support members. Locks on the ends of the arms can removably lock the hub to the cages. Because the hub is removable, the cage with coiled rod can be shipped separate from the hub, thereby significantly reducing the transportation weight. Preferably, the cage has a diameter of 14-ft so two cages can be held on a stand and can be transported in overseas containers. In this way, the coiled rod in the cage can be transported to various areas in less costly and time-consuming ways than currently available. | 03-31-2011 |
Hermann Basler, Stony Plain CA
| Patent application number | Description | Published |
|---|---|---|
| 20110150596 | SHEAR COUPLING ASSEMBLY FOR USE WITH ROTARY AND RECIPROCATING PUMPS - A shear coupling assembly utilizes a second coupling member, a first coupling member and a locking member which is inserted into a bore in the first coupling member to connect between the second coupling member and the first coupling member. In embodiments where a pretension is applied to the shear neck, the locking member maintains the pretension in the shear neck. The bore of the first coupling member has a profiled section which corresponds to a profiled section on the second coupling member which when mated together permit torque to be transferred for co-rotating the second coupling member with the first coupling member for use in rotary pump operations. Advantageously, the profiled portions and the shear neck are encased in the bore of the shear coupling assembly and are protected from corrosive wellbore fluids. | 06-23-2011 |
James Robert Basler, Redwood City, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100032207 | Method and System for Forming a Non-Circular Borehole - System and methods for creating shaped, non-circular boreholes in rocks especially for use with geothermal heat pump applications and for increasing wellbore support in applications such as horizontal oil and gas drilling are described. The systems and methods when applied to geothermal heat pumps create an elliptical shaped hole that is optimized for placing heat transfer tubes with a minimum of grout used. The significantly reduced cross-sectional area of the elliptical borehole also increases the overall drilling rate in rock and especially in hard rocks. In horizontal hard-rock drilling, creation of a horizontal non-circular borehole or modification of a circular borehole to a non-circular geometry is used to stabilize the borehole prior to casing insertion, and may also allow the use of lower mud pressures improving drilling rates. The system uses a non-contacting drilling system which in one embodiment uses a supersonic flame jet drilling system with a movable nozzle that swings between pivot points. In a second embodiment the elliptical shaped hole is created by an abrasive fluid or particle bearing-fluid or air jet drill that moves between pivot points. In another embodiment a non-contacting drill can use dual parallel nutating nozzles that create a pair of overlapping circular holes. The non-circular shaped hole is created by either the high temperature flame or water-particle jet or chemically active fluid jet as it removes rock material by erosion, dissolution and or thermal spalling. Modifications of circular boreholes to a generally elliptical shape can also be done using milling or jetting techniques. | 02-11-2010 |
| 20110174537 | Method and System for Forming a Non-Circular Borehole - System and methods for creating shaped, non-circular boreholes in rocks especially for use with geothermal heat pump applications and for increasing wellbore support in applications such as horizontal oil and gas drilling are described. The systems and methods when applied to geothermal heat pumps create an elliptical shaped hole that is optimized for placing heat transfer tubes with a minimum of grout used. The significantly reduced cross-sectional area of the elliptical borehole also increases the overall drilling rate in rock and especially in hard rocks. In horizontal hard-rock drilling, creation of a horizontal non-circular borehole or modification of a circular borehole to a non-circular geometry is used to stabilize the borehole prior to casing insertion, and may also allow the use of lower mud pressures improving drilling rates. The system uses a non-contacting drilling system which in one embodiment uses a supersonic flame jet drilling system with a movable nozzle that swings between pivot points. In a second embodiment the elliptical shaped hole is created by an abrasive fluid or particle bearing-fluid or air jet drill that moves between pivot points. In another embodiment a non-contacting drill can use dual parallel nutating nozzles that create a pair of overlapping circular holes. The non-circular shaped hole is created by either the high temperature flame or water-particle jet or chemically active fluid jet as it removes rock material by erosion, dissolution and or thermal spalling. Modifications of circular boreholes to a generally elliptical shape can also be done using milling or jetting techniques. | 07-21-2011 |
Jason F. Basler, Los Gatos, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090043771 | SYSTEMS, METHODS AND COMPUTER PRODUCTS FOR ENSURING DATA INTEGRITY OF A STORAGE SYSTEM - Systems, methods, and computer products for ensuring data integrity of a storage system. Exemplary embodiments include a method for ensuring data integrity in a storage system, the method including creating a data set using a repeatable pattern to establish expected values, storing the data set into the storage system using a defined interface of the system, extracting the data from the storage system using a defined interface of the system and comparing the extracted data against the expected values established by the known pattern. | 02-12-2009 |
| 20100146514 | TEST MANAGEMENT SYSTEM AND METHOD - An execution management method includes providing an execution plan, balancing an execution load across a plurality of servers, automatically interpreting the execution plan, and re-driving a failed test to another of the plurality of servers if the test case fails on an originally selected available server. The execution plan includes a plurality of test cases and criteria corresponding to the test cases. More than one of the plurality of test cases may be run on each of the plurality of servers at a same time in parallel. Each of the plurality of servers is run independently. | 06-10-2010 |
Jason Ferris Basler, Los Gatos, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090216816 | METHOD FOR APPLICATION BACKUP IN THE VMWARE CONSOLIDATED BACKUP FRAMEWORK - Systems and methods for backing up applications executing on a virtual machine are provided. The method comprises submitting a first notification to a remote computing system to prepare an application running on a virtual machine for backup, such that application data consistency is maintained during the backup process; receiving a second notification from the remote computing system, indicating that the application is prepared for backup; creating a snapshot of the virtual machine in response to the second notification; and receiving application data from the computing system to process the snapshot and complete an application-specific backup for the virtual machine. | 08-27-2009 |
| 20090216970 | APPARATUS, SYSTEM, AND METHOD FOR VIRTUAL MACHINE BACKUP - An apparatus, system, and method are disclosed for a virtual machine backup. A name module establishes an administrative machine name for a virtual machine. A space module associates at least one administrative name space with the administrative machine name. A backup module backs up files belonging to the virtual machine using a backup proxy, wherein the files are segregated under the administrative machine name and are accessible using only a secure key belonging to the virtual machine and without using a backup proxy secure key. A mask module masks out pathname components for each backup file pathname so that the backup file pathname is equivalent to a virtual machine file pathname. | 08-27-2009 |
Joshua R. Basler, Palo Alto, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110256609 | Compositions And Methods Comprising Variant Microbial Proteases - The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant subtilisins suitable for laundry cleaning applications. | 10-20-2011 |
| 20110262999 | Compositions and Methods Comprising Protease Variants - The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions. | 10-27-2011 |
Joshua Roy Basler, Palo Alto, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110237487 | FABRIC AND HOME CARE PRODUCTS - This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such compositions provide improved cleaning and freshness. Such cold water proteases may be derived from parent enzymes, including BPN′ subtilisin and subtilisin derived from | 09-29-2011 |
Marek Basler, Prague CZ
| Patent application number | Description | Published |
|---|---|---|
| 20100239550 | MUTANT CyaA POLYPEPTIDES AND POLYPEPTIDE DERIVATIVES SUITABLE FOR THE DELIVERY OF IMMUNOGENIC MOLECULES INTO A CELL - The invention relates to mutant CyaA/E570Q+K860 polypeptides suitable for use as proteinaceous vectors for delivering one or more molecules of interest into a cell, in particular into a cell expressing the CD11b receptor. The invention further relates to polypeptide derivatives suitable for eliciting an immune response in a host. | 09-23-2010 |
Merek Basler, Prague CZ
| Patent application number | Description | Published |
|---|---|---|
| 20120071393 | Mutant CyaA Polypeptides and Polypeptide Derivatives Suitable for the Delivery of Immunogenic Molecules Into a Cell - The invention relates to mutant CyaA/E570Q+K860 polypeptides suitable for use as proteinaceous vectors for delivering one or more molecules of interest into a cell, in particular into a cell expressing the CD11b receptor. The invention further relates to polypeptide derivatives suitable for eliciting an immune response in a host. | 03-22-2012 |
Roger Wolfgang Basler US
| Patent application number | Description | Published |
|---|---|---|
| 20110131738 | DETERGENT COMPOSITION - The present invention relates to new compositions comprising compounds, which are molecular combinations of a phthalocyanine and a mono-azo dyestuff linked via specific linking groups. Further aspects are an improved shading process for textile materials and also use of these shading compositions for shading textiles. | 06-09-2011 |